erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Bursitis D002062 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Acute Lung Injury D055371 33 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Pericarditis D010493 6 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Heart Block D006327 3 associated lipids
Long QT Syndrome D008133 10 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Gonorrhea D006069 7 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Endometritis D004716 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Constipation D003248 8 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Varicose Ulcer D014647 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Hand Dermatoses D006229 5 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Splenomegaly D013163 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Endocarditis D004696 4 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Cundliffe E and McQuillen K Peptide bond formation: the effects of antibiotics on the puromycin reaction. 1968 J. Gen. Microbiol. pmid:4968006
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Mao JC and Putterman M Accumulation in gram-postive and gram-negative bacteria as a mechanism of resistance to erythromycin. 1968 J. Bacteriol. pmid:4966821
Ferrando R [Absorption and metabolism of antibiotics. Residues in the tissues]. 1968 Bibl Nutr Dieta pmid:4868400
Frisby BR A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics. 1968 Med. J. Aust. pmid:4967052
Lindsay AE and Truxal AC Oral therapy in bacterial endocarditis. 1968 Rocky Mt Med J pmid:4967211
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Henriksen SD and Bovre K Moraxella kingii sp.nov., a haemolytic, saccharolytic species of the genus Moraxella. 1968 J. Gen. Microbiol. pmid:5185818
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Erythromycin compared with phenoxymethyl-penicillin and tetracycline. 1968 Practitioner pmid:4972106
Ahmed A Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis. 1968 Biochim. Biophys. Acta pmid:4972350
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Jackson DM The burnt child and his family. What the burnt child goes through. 1968 Proc. R. Soc. Med. pmid:4972634
Sabath LD et al. Excretion of erythromycin and its enhanced activity in urine against gram-negative bacilli with alkalinization. 1968 J. Lab. Clin. Med. pmid:4972710
Lenoski EF et al. Drug trials in acute otitis media. 1968 Curr Ther Res Clin Exp pmid:4972759
Ramos e Silva J [Current treatment of syphilis, particularly of early syphilis]. 1968 Rev Bras Med pmid:5707186
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Hejzlar M et al. Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. 1968 J Hyg Epidemiol Microbiol Immunol pmid:4977454
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Paterson PY and Madden GM Occurrence and erythromycin susceptibility of penicillin-resistant Viridans streptococci in rheumatic fever patients on oral penicillin prophylaxis. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735376
McGehee RF R et al. Resistance of Staphylococcus aureus to lincomycin, clinimycin, and erythromycin. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735385
Wick WE and Mallett GE New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735386
Kuntsevich LD [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. 1968 Vestn Dermatol Venerol pmid:5738081
Pezzìca R [Damage caused by associated antibiotics in domiciliary therapy of acute febrile diseases. Film: "These 3 neutrophil leukocytes are from a 4-year-old child on the fourth day of treatment with CAF in average therapeutic doses. The toxic granulations in the protoplasm are clearly visible"]. 1968 Minerva Pediatr. pmid:5739033
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Studnitsin AA and Pashkov BM [Results of discussions on the treatment of syphilis]. 1968 Vestn Dermatol Venerol pmid:5742374
Martini J et al. [Treatment of acute male gonococcal urethritis with a single dosis of erythromycin-stearate]. 1968 Rev Med Chil pmid:5746282
Mitsui Y and Suzuki H [Evaluation of colistin-erythromycin ointment and solution in ophthalmology]. 1968 Nihon Ganka Kiyo pmid:5748900
Pulverer G [Studies with lysostaphin. I. Lysostaphin sensitivity of 355 strains of Staph. aureus of human origin]. 1968 Z Med Mikrobiol Immunol pmid:5710870
Mao JC and Wiegand RG Mode of action of macrolides. 1968 Biochim. Biophys. Acta pmid:5649911
da Silva WB et al. [Use of a chloramphenicol-erythromycin combination in the treatment of lung diseases in children]. 1968 Hospital (Rio J) pmid:5308493
Jones PH and Rowley EK Chemical modifications of erythromycin antibiotics. I. 3'-de(dimethylamino)erythromycin A and B. 1968 J. Org. Chem. pmid:5636610
Thomas DY and Wilkie D Recombination of mitochondrial drug-resistance factors in Saccharomyces cerevisiae. 1968 Biochem. Biophys. Res. Commun. pmid:5637042
Amato Neto V and Wanderley RA [Use of an erythromycin stearate preparation, of regulated intestinal release in the treatment of intestinal amebiasis]. 1968 Hospital (Rio J) pmid:5311770
Smith CC et al. Bacterial substitution for staphylococcal infection. 1968 N. Z. Med. J. pmid:4231513
Bülow P A new epidemic phage type of Staphylococcus aureus. I. The experimental typing phage 6557'. 1968 Acta Pathol Microbiol Scand pmid:4231992
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Beck LE Some recent advances and trends in drug therapy. 2. Antibiotics. 1968 Med. J. Aust. pmid:4233563
Jayaraman J and Goldberg IH Localization of sparsomycin action to the peptide-bond-forming step. 1968 Biochemistry pmid:4921281
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Ezekiel DH and Elkins BN The stimulation of ribonucleic acid synthesis by ribosome inhibitors in amino acid-starved Escherichia coli. 1968 Biochim. Biophys. Acta pmid:4234520
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Schmitt BD Indications for tetracycline in pediatrics. 1968 Pediatrics pmid:5657689
Forshaw J Penicillin-induced granulopenia. 1968 Br Med J pmid:5662555
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Mezey E et al. Serum alcohol dehydrogenase, an indicator of intrahepatic cholestasis. 1968 N. Engl. J. Med. pmid:5662777
The macrolides and lincomycin. 1968 Br Med J pmid:5662980
Simon C and Latz E [Antibiotic therapy of staphylococcal infections. The influence of chloramphenicol and erythromycin on the bactericidal effect of penicillin G and methicillin in vitro]. 1968 Med Welt pmid:5663162
Narasimhan MJ and Ganla VG The broad-spectrum and the macrolide antibiotics and the ciliary barrier. 1968 Hindustan Antibiot Bull pmid:5663533
Bertrand JL [Combination of propionyl-erythromycin, tetracycline and lysozyme in anti-infective therapy in adults and children]. 1968 Lyon Med pmid:5664960
Davis CM et al. The value of neomycin in a neomycin-steroid cream. 1968 JAMA pmid:4294840
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Banaszek A et al. Thin-layer and column chromatography of erythromycins and some degradation products. 1968 J. Chromatogr. pmid:4295864
Martin JR and Perun TJ Studies on the biosynthesis of the erythromycins. 3. Isolation and structure of 5-deoxy-5-oxoerythronolide B, a shunt metabolite of erythromycin biosynthesis. 1968 Biochemistry pmid:4297053
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Dixon JM Group A Streptococcus resistant to erythromycin and lincomycin. 1968 Can Med Assoc J pmid:4386993
Nakajima Y et al. A mode of resistance to macrolide antibiotics in Staphylococcus aureus. 1968 Jpn. J. Microbiol. pmid:5303510
Arret B and Eckert J New developments in antibiotic interference thresholds of microbial assays. 1968 J Pharm Sci pmid:4297949
McCabe WR and Lorian V Comparison of the antibacterial activity of rifampicin and other antibiotics. 1968 Am. J. Med. Sci. pmid:4387027
Rouquès L [Scarlet fever in 1968]. 1968 Presse Med pmid:5305215
Winningham DG et al. Diffusion of antibiotics from plasma into prostatic fluid. 1968 Nature pmid:4298194
Peterson JM and Guild WR Fractionated strands of bacterial deoxyribonucleic acid. 3. Transformation efficiencies and rates of phenotypic expression. 1968 J. Bacteriol. pmid:4387147
Grady JE Recent developments in lincomycin research. 1968 Int Z Klin Pharmakol Ther Toxikol pmid:4388454
Sabath LD et al. Serum glutamic oxalacetic transaminase. False elevations during administration of erythromycin. 1968 N. Engl. J. Med. pmid:5686481
Rajka G Treatment of gonorrhoea patients with intolerance to penicillin. 1968 Acta Derm. Venereol. pmid:4177580
Grimble AS Possible Mycoplasma hominis urethritis rvealed by differing responses of "abacterial urethritis" to treatment with tetracycline and erythromycin. 1968 Br J Vener Dis pmid:5687045
Weisblum B and Davies J Antibiotic inhibitors of the bacterial ribosome. 1968 Bacteriol Rev pmid:4179192
Ivanitskaia LP and Manafova NA [Study of sensitivity to antibiotics in cultures of Anacystis nidulans and Chlorella sp. in relation to their possible use as tests in selection of new biologically active compounds from Actinomycetes]. 1968 Antibiotiki pmid:4180805
Dohlman CH and Boruchoff SA Penetrating keratoplasty. 1968 Int Ophthalmol Clin pmid:4904228