erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cundliffe E and McQuillen K | Peptide bond formation: the effects of antibiotics on the puromycin reaction. | 1968 | J. Gen. Microbiol. | pmid:4968006 |
Cundliffe E and McQuillen K | Peptide-bond formation: the modes of action of chloramphenicol, sparsomycin and erythromycin. | 1968 | J. Gen. Microbiol. | pmid:4968007 |
Igari J and Kano M | [Basic study on chemotherapy of urinary tract infection. 3. Effect of urine pH on antibacterial activity of macrolides, lincomycin and clinimycin on Escherichia coli]. | 1968 | Jpn J Antibiot | pmid:4887887 |
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Garanin BA | [Sensitivity toward antibiotics of Shigella Sonnei of individual fermentative types based on data from a hospital for communicable diseases during 1966]. | 1968 | Antibiotiki | pmid:4877060 |
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Ross S | Erythromycin, oleandomycin and triacetyloleandomycin. | 1968 | Pediatr. Clin. North Am. | pmid:4867776 |
Mao JC and Putterman M | Accumulation in gram-postive and gram-negative bacteria as a mechanism of resistance to erythromycin. | 1968 | J. Bacteriol. | pmid:4966821 |
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Frisby BR | A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics. | 1968 | Med. J. Aust. | pmid:4967052 |
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Oleinick NL et al. | Nonidentity of the site of action of erythromycin A and chloramphenicol on Bacillus subtilis ribosomes. | 1968 | Biochim. Biophys. Acta | pmid:4967315 |
Osman HG et al. | Utilization of Egyptian raw by-products for the erythromycin production by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4989340 |
Henriksen SD and Bovre K | Moraxella kingii sp.nov., a haemolytic, saccharolytic species of the genus Moraxella. | 1968 | J. Gen. Microbiol. | pmid:5185818 |
Choudhuri KK and Basu Mallick KC | Study of antibiotic-resistant staphylococci isolated from different sources and their role in pathogenicity. | 1968 | Indian J. Med. Res. | pmid:5186305 |
Robertson MH | Tetracycline-resistant streptococci in South-west Essex: a continuing survey. | 1968 | Br Med J | pmid:5186976 |
Postnikova AA | [On the characteristics of staphylococci in chronic osteomyelitis in children]. | 1968 | Antibiotiki | pmid:5187169 |
Zygmunt WA et al. | Comparative inhibition of methicillin-resistant strains of Staphylococcus aureus by lysostaphin and other antibiotics. | 1968 | Appl Microbiol | pmid:5187926 |
Corse J and Williams RE | Antibiotic resistance of coagulase-negative staphylococci and micrococci. | 1968 | J. Clin. Pathol. | pmid:5191722 |
Obojska K and Zawadzka-Gralewicz J | [Combined effect of colistin with neomycin, penicillins and erythromycin on Corynebacterium diphtheriae]. | 1968 | Med Dosw Mikrobiol | pmid:4970248 |
Sabath LD et al. | Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria. | 1968 | Appl Microbiol | pmid:4970991 |
Jewett JF et al. | Childbed fever--a continuing entity. | 1968 | JAMA | pmid:4971028 |
Iats'ko VA | [On the dynamics of sensitivity to antibiotics of different microorganisms, isolated from patients of a surgical section]. | 1968 | Antibiotiki | pmid:4971186 |
Betinová M | [Effect of tetracyclines, macrolide antibiotics, and sigmamycin on staphylococci in vitro]. | 1968 | Biologia | pmid:4971503 |
Erythromycin compared with phenoxymethyl-penicillin and tetracycline. | 1968 | Practitioner | pmid:4972106 | |
Ahmed A | Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis. | 1968 | Biochim. Biophys. Acta | pmid:4972350 |
De Vries JA et al. | Adjunctive use of antibiotics in traumatic dental procedures. | 1968 | Int Z Klin Pharmakol Ther Toxikol | pmid:4972570 |
Jackson DM | The burnt child and his family. What the burnt child goes through. | 1968 | Proc. R. Soc. Med. | pmid:4972634 |
Sabath LD et al. | Excretion of erythromycin and its enhanced activity in urine against gram-negative bacilli with alkalinization. | 1968 | J. Lab. Clin. Med. | pmid:4972710 |
Lenoski EF et al. | Drug trials in acute otitis media. | 1968 | Curr Ther Res Clin Exp | pmid:4972759 |
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Monnier J and Bourse R | [Antibacterial activity in vitro of a new rifamycin: rifamide]. | 1968 | Pathol Biol | pmid:4972879 |
Poralla K and Zähner H | [Metabolic products of microorganisms. 62. The inhibition of the incorporation of threonine in sRNA in cell-free systems and of the synthesis of proteins and nucleic acids in the cell by the antibiotic borrelidin]. | 1968 | Arch Mikrobiol | pmid:4974079 |
Rotheim MB and Ravin AW | Inactivation and reversion of multisite streptomycin resistance mutations of Pneumococcus. | 1968 | Mol. Gen. Genet. | pmid:5713396 |
Onodera T et al. | Effect of fluid and antibiotic administration on experimental fecal peritonitis. | 1968 | Tohoku J. Exp. Med. | pmid:5715596 |
Hejzlar M et al. | Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. | 1968 | J Hyg Epidemiol Microbiol Immunol | pmid:4977454 |
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Paterson PY and Madden GM | Occurrence and erythromycin susceptibility of penicillin-resistant Viridans streptococci in rheumatic fever patients on oral penicillin prophylaxis. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735376 |
McGehee RF R et al. | Resistance of Staphylococcus aureus to lincomycin, clinimycin, and erythromycin. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735385 |
Wick WE and Mallett GE | New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735386 |
Kuntsevich LD | [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. | 1968 | Vestn Dermatol Venerol | pmid:5738081 |
Pezzìca R | [Damage caused by associated antibiotics in domiciliary therapy of acute febrile diseases. Film: "These 3 neutrophil leukocytes are from a 4-year-old child on the fourth day of treatment with CAF in average therapeutic doses. The toxic granulations in the protoplasm are clearly visible"]. | 1968 | Minerva Pediatr. | pmid:5739033 |
Renzini G et al. | [Study of the antibacterial activity and of the serum and tissue levels produced in animals by the administration of two antibiotic associations]. | 1968 | Antibiotica | pmid:5740898 |
Studnitsin AA and Pashkov BM | [Results of discussions on the treatment of syphilis]. | 1968 | Vestn Dermatol Venerol | pmid:5742374 |
Martini J et al. | [Treatment of acute male gonococcal urethritis with a single dosis of erythromycin-stearate]. | 1968 | Rev Med Chil | pmid:5746282 |
Mitsui Y and Suzuki H | [Evaluation of colistin-erythromycin ointment and solution in ophthalmology]. | 1968 | Nihon Ganka Kiyo | pmid:5748900 |
Pulverer G | [Studies with lysostaphin. I. Lysostaphin sensitivity of 355 strains of Staph. aureus of human origin]. | 1968 | Z Med Mikrobiol Immunol | pmid:5710870 |
Mao JC and Wiegand RG | Mode of action of macrolides. | 1968 | Biochim. Biophys. Acta | pmid:5649911 |
da Silva WB et al. | [Use of a chloramphenicol-erythromycin combination in the treatment of lung diseases in children]. | 1968 | Hospital (Rio J) | pmid:5308493 |
Jones PH and Rowley EK | Chemical modifications of erythromycin antibiotics. I. 3'-de(dimethylamino)erythromycin A and B. | 1968 | J. Org. Chem. | pmid:5636610 |
Thomas DY and Wilkie D | Recombination of mitochondrial drug-resistance factors in Saccharomyces cerevisiae. | 1968 | Biochem. Biophys. Res. Commun. | pmid:5637042 |
Amato Neto V and Wanderley RA | [Use of an erythromycin stearate preparation, of regulated intestinal release in the treatment of intestinal amebiasis]. | 1968 | Hospital (Rio J) | pmid:5311770 |
Smith CC et al. | Bacterial substitution for staphylococcal infection. | 1968 | N. Z. Med. J. | pmid:4231513 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. I. The experimental typing phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231992 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 2. Characteristics of staphylococci lysed by phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231993 |
Breitfellner G and Neuhold R | [Yearly variations of the lysotype and resistance picture of staphylococci]. | 1968 | Wien. Klin. Wochenschr. | pmid:4232544 |
Beck LE | Some recent advances and trends in drug therapy. 2. Antibiotics. | 1968 | Med. J. Aust. | pmid:4233563 |
Jayaraman J and Goldberg IH | Localization of sparsomycin action to the peptide-bond-forming step. | 1968 | Biochemistry | pmid:4921281 |
Herrschaft H | [On the participation of the central nervous system in Behcet's disease]. | 1968 | Dtsch. Med. Wochenschr. | pmid:5655850 |
Ezekiel DH and Elkins BN | The stimulation of ribonucleic acid synthesis by ribosome inhibitors in amino acid-starved Escherichia coli. | 1968 | Biochim. Biophys. Acta | pmid:4234520 |
Biró L and Iván E | Study of bactericidal and bacteriostatic antibiotics in animals with normal and suppressed immunity. | 1968 | Chemotherapy | pmid:5656115 |
Wyman JB et al. | Pancreatic, hepatic, and renal excretion of antibiotics in dogs. Observations on erythromycin, lincomycin, kanamycin, and colistimethate excretion. | 1968 | Arch Surg | pmid:5657416 |
Hashimoto H et al. | Drug resistance of staphylococci. IX. Inducible resistance to macrolide antibiotics in Staphylococcus aureus. | 1968 | Jpn. J. Microbiol. | pmid:4236812 |
Schmitt BD | Indications for tetracycline in pediatrics. | 1968 | Pediatrics | pmid:5657689 |
Forshaw J | Penicillin-induced granulopenia. | 1968 | Br Med J | pmid:5662555 |
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Mezey E et al. | Serum alcohol dehydrogenase, an indicator of intrahepatic cholestasis. | 1968 | N. Engl. J. Med. | pmid:5662777 |
The macrolides and lincomycin. | 1968 | Br Med J | pmid:5662980 | |
Simon C and Latz E | [Antibiotic therapy of staphylococcal infections. The influence of chloramphenicol and erythromycin on the bactericidal effect of penicillin G and methicillin in vitro]. | 1968 | Med Welt | pmid:5663162 |
Narasimhan MJ and Ganla VG | The broad-spectrum and the macrolide antibiotics and the ciliary barrier. | 1968 | Hindustan Antibiot Bull | pmid:5663533 |
Bertrand JL | [Combination of propionyl-erythromycin, tetracycline and lysozyme in anti-infective therapy in adults and children]. | 1968 | Lyon Med | pmid:5664960 |
Davis CM et al. | The value of neomycin in a neomycin-steroid cream. | 1968 | JAMA | pmid:4294840 |
Levin HS and Kagan BM | Antimicrobial agents: pediatric dosage, routes of administration and preparation procedures for parenteral therapy. | 1968 | Pediatr. Clin. North Am. | pmid:4295551 |
Banaszek A et al. | Thin-layer and column chromatography of erythromycins and some degradation products. | 1968 | J. Chromatogr. | pmid:4295864 |
Martin JR and Perun TJ | Studies on the biosynthesis of the erythromycins. 3. Isolation and structure of 5-deoxy-5-oxoerythronolide B, a shunt metabolite of erythromycin biosynthesis. | 1968 | Biochemistry | pmid:4297053 |
Sanders S and Norman AP | The bacterial flora of the upper respiratory tract in children with severe asthma. | 1968 | J Allergy | pmid:5300899 |
Chevallier MR et al. | [Halogenation of ribonucleic acids. VI. Influence of bromination on the transforming activity of Haemophilus influenzae DNA]. | 1968 | Bull. Soc. Chim. Biol. | pmid:4297076 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
Oppenheimer S and Turek M | Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. | 1968 | Am. J. Med. Sci. | pmid:4386951 |
Noonan JA et al. | Cerebral and cardiac complications from bacterial endocarditis. A successfully managed case with unusual complications. | 1968 | Am. J. Dis. Child. | pmid:5303294 |
Dixon JM | Group A Streptococcus resistant to erythromycin and lincomycin. | 1968 | Can Med Assoc J | pmid:4386993 |
Nakajima Y et al. | A mode of resistance to macrolide antibiotics in Staphylococcus aureus. | 1968 | Jpn. J. Microbiol. | pmid:5303510 |
Arret B and Eckert J | New developments in antibiotic interference thresholds of microbial assays. | 1968 | J Pharm Sci | pmid:4297949 |
McCabe WR and Lorian V | Comparison of the antibacterial activity of rifampicin and other antibiotics. | 1968 | Am. J. Med. Sci. | pmid:4387027 |
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Winningham DG et al. | Diffusion of antibiotics from plasma into prostatic fluid. | 1968 | Nature | pmid:4298194 |
Peterson JM and Guild WR | Fractionated strands of bacterial deoxyribonucleic acid. 3. Transformation efficiencies and rates of phenotypic expression. | 1968 | J. Bacteriol. | pmid:4387147 |
Grady JE | Recent developments in lincomycin research. | 1968 | Int Z Klin Pharmakol Ther Toxikol | pmid:4388454 |
Sabath LD et al. | Serum glutamic oxalacetic transaminase. False elevations during administration of erythromycin. | 1968 | N. Engl. J. Med. | pmid:5686481 |
Rajka G | Treatment of gonorrhoea patients with intolerance to penicillin. | 1968 | Acta Derm. Venereol. | pmid:4177580 |
Grimble AS | Possible Mycoplasma hominis urethritis rvealed by differing responses of "abacterial urethritis" to treatment with tetracycline and erythromycin. | 1968 | Br J Vener Dis | pmid:5687045 |
Weisblum B and Davies J | Antibiotic inhibitors of the bacterial ribosome. | 1968 | Bacteriol Rev | pmid:4179192 |
Ivanitskaia LP and Manafova NA | [Study of sensitivity to antibiotics in cultures of Anacystis nidulans and Chlorella sp. in relation to their possible use as tests in selection of new biologically active compounds from Actinomycetes]. | 1968 | Antibiotiki | pmid:4180805 |
Dohlman CH and Boruchoff SA | Penetrating keratoplasty. | 1968 | Int Ophthalmol Clin | pmid:4904228 |