erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lakritz J et al. | Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals. | 1997 | Am. J. Vet. Res. | pmid:8989497 |
| MARSHALL RT et al. | THE EFFECTS OF BLOOD AND NONFAT MILK CONSTITUTENTS ON DIFFUSION OF BACTERIAL INHIBITORS IN AGAR MEDIUMS. | 1964 | Am. J. Vet. Res. | pmid:14266843 |
| PLASTRIDGE WN et al. | ANTIBIOTIC SENSITIVITY OF PHYSIOLOGIC GROUPS OF MICROAEROPHILIC VIBRIOS. | 1964 | Am. J. Vet. Res. | pmid:14266885 |
| Lester GD et al. | Effect of erythromycin lactobionate on myoelectric activity of ileum, cecum, and right ventral colon, and cecal emptying of radiolabeled markers in clinically normal ponies. | 1998 | Am. J. Vet. Res. | pmid:9522953 |
| FLORESTANO HJ and BAHLER ME | Chemotherapeutic properties of erythromycin alone and in combination with sulfamerazine. | 1955 | Am. J. Vet. Res. | pmid:13228887 |
| Regnery RL et al. | Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats. | 1996 | Am. J. Vet. Res. | pmid:8950424 |
| Ringger NC et al. | Effect of bethanechol or erythromycin on gastric emptying in horses. | 1996 | Am. J. Vet. Res. | pmid:8950433 |
| Lakritz J et al. | Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals. | 2000 | Am. J. Vet. Res. | pmid:10951982 |
| Ramstedt KL et al. | Changes in gallbladder volume in healthy dogs after food was withheld for 12 hours followed by ingestion of a meal or a meal containing erythromycin. | 2008 | Am. J. Vet. Res. | pmid:18447796 |
| Lakritz J et al. | Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals. | 2000 | Am. J. Vet. Res. | pmid:10976728 |
| Khan SA et al. | Characterization of erythromycin-resistant methylase genes from multiple antibiotic resistant Staphylococcus spp isolated from milk samples of lactating cows. | 2000 | Am. J. Vet. Res. | pmid:10976747 |
| Lakritz J et al. | Comparison of microbiologic and high-performance liquid chromatography assays to determine plasma concentrations, pharmacokinetics, and bioavailability of erythromycin base in plasma of foals after intravenous or intragastric administration. | 1999 | Am. J. Vet. Res. | pmid:10211682 |
| Ziv G et al. | Mode of transfer of antibiotics from treated to nontreated quarters in dairy cows. | 1974 | Am. J. Vet. Res. | pmid:4133826 |
| Afshari GR et al. | Effect of parenteral administration of ivermectin and erythromycin on abomasal emptying rate in suckling calves. | 2009 | Am. J. Vet. Res. | pmid:19335110 |
| Libal MC | Comparison of minimal inhibitory concentration and disk-diffusion antimicrobic sensitivity testing of bacterial pathogens isolated from food animals. | 1985 | Am. J. Vet. Res. | pmid:3159322 |
| Koenig JB et al. | Binding of radiolabeled porcine motilin and erythromycin lactobionate to smooth muscle membranes in various segments of the equine gastrointestinal tract. | 2002 | Am. J. Vet. Res. | pmid:12428665 |
| Wittek T and Constable PD | Assessment of the effects of erythromycin, neostigmine, and metoclopramide on abomasal motility and emptying rate in calves. | 2005 | Am. J. Vet. Res. | pmid:15822601 |
| Wilson RC et al. | Serum erythromycin concentration in sheep fed two diets. | 1984 | Am. J. Vet. Res. | pmid:6742574 |
| Burrows GE et al. | Serum and tissue concentrations of erythromycin in calves with induced pneumonic pasteurellosis. | 1989 | Am. J. Vet. Res. | pmid:2774339 |
| Smith JA et al. | Inhibitory and lethal activities of rosaramicin, erythromycin, and clindamycin against Campylobacter fetus subsp jejuni and intestinalis. | 1983 | Am. J. Vet. Res. | pmid:6625312 |
| Kinoshita T et al. | Impact of age-related alteration of plasma alpha 1-acid glycoprotein concentration on erythromycin pharmacokinetics in pigs. | 1995 | Am. J. Vet. Res. | pmid:7771705 |
| Nouri M and Constable PD | Effect of parenteral administration of erythromycin, tilmicosin, and tylosin on abomasal emptying rate in suckling calves. | 2007 | Am. J. Vet. Res. | pmid:18052746 |
| Goswami SK et al. | Erythromycin inhibits respiratory glycoconjugate secretion from human airways in vitro. | 1990 | Am. Rev. Respir. Dis. | pmid:2404441 |
| Mukae H et al. | Elevation of tumor-associated carbohydrate antigens in patients with diffuse panbronchiolitis. | 1993 | Am. Rev. Respir. Dis. | pmid:8103656 |
| Ichikawa Y et al. | Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. | 1992 | Am. Rev. Respir. Dis. | pmid:1626803 |
| Parker MM et al. | Unresponsiveness of Legionella bozemanii pneumonia to erythromycin administration despite in vitro sensitivity. | 1983 | Am. Rev. Respir. Dis. | pmid:6638688 |
| Datta JS and Raff MJ | Actinomycotic pleuropericarditis. | 1974 | Am. Rev. Respir. Dis. | pmid:4277986 |
| Reisz G et al. | The effect of erythromycin on theophylline pharmacokinetics in chronic bronchitis. | 1983 | Am. Rev. Respir. Dis. | pmid:6846940 |
| Kadota J et al. | A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis. | 1993 | Am. Rev. Respir. Dis. | pmid:8420410 |
| Pachon J et al. | Severe community-acquired pneumonia. Etiology, prognosis, and treatment. | 1990 | Am. Rev. Respir. Dis. | pmid:2382902 |
| Heifets LB et al. | Clarithromycin minimal inhibitory and bactericidal concentrations against Mycobacterium avium. | 1992 | Am. Rev. Respir. Dis. | pmid:1532486 |
| Ruf B et al. | Acquired resistance of MAI to clarithromycin. | 1992 | Am. Rev. Respir. Dis. | pmid:1533999 |
| Kuperman AS and Fernandez RB | Subacute staphylococcal pneumonia. | 1970 | Am. Rev. Respir. Dis. | pmid:5410079 |
| Finland M | Pneumonia and pneumococcal infections, with special reference to pneumococcal pneumonia. The 1979 J. Burns Amberson lecture. | 1979 | Am. Rev. Respir. Dis. | pmid:39481 |
| Chemoprophylaxis of chronic bronchitis. A statement by the Committee on Therapy. | 1971 | Am. Rev. Respir. Dis. | pmid:5125186 | |
| Davis SD et al. | Disseminated osteomyelitis due to "Battey" mycobacteria. | 1966 | Am. Rev. Respir. Dis. | pmid:5908093 |
| Sakata K et al. | Erythromycin inhibits the production of elastase by Pseudomonas aeruginosa without affecting its proliferation in vitro. | 1993 | Am. Rev. Respir. Dis. | pmid:8214925 |
| Edelstein PH et al. | Antimicrobial therapy of experimentally induced Legionnaires' disease in guinea pigs. | 1984 | Am. Rev. Respir. Dis. | pmid:6333840 |
| Nelson S et al. | Erythromycin-induced suppression of pulmonary antibacterial defenses. A potential mechanism of superinfection in the lung. | 1987 | Am. Rev. Respir. Dis. | pmid:3314615 |
| Srinivasan G et al. | Branhamella catarrhalis pneumonia: report of two cases and review of the literature. | 1981 | Am. Rev. Respir. Dis. | pmid:7235378 |
| Hahn D | Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. | 1993 | Am. Rev. Respir. Dis. | pmid:8466109 |
| Timberger RJ and Armstrong D | Ornithosis without direct bird exposure: response to erythromycin. Report of a case. | 1969 | Am. Rev. Respir. Dis. | pmid:5815139 |
| Dautzenberg B et al. | Activity of clarithromycin against Mycobacterium avium infection in patients with the acquired immune deficiency syndrome. A controlled clinical trial. | 1991 | Am. Rev. Respir. Dis. | pmid:1832527 |
| Doyle WM et al. | Pulmonary disease caused by Mycobacterium xenopei. | 1968 | Am. Rev. Respir. Dis. | pmid:5647216 |
| HALLETT WY et al. | Chemoprophylaxis in chronic obstructive pulmonary emphysema: a twelve-week study with erythromycin. | 1959 | Am. Rev. Respir. Dis. | pmid:14399110 |
| MONTGOMERY CH and KNOX JM | Erythromycin in the treatment of early syphilis; a preliminary report. | 1959 | AMA Arch Derm | pmid:13669748 |
| ROBINSON HM et al. | Erythromycin in treatment of dermatoses; report on 1,695 patients. | 1954 | AMA Arch Derm Syphilol | pmid:13188466 |
| WAISBREN BA | Antibiotic treatment of bacterial endocarditis due to enterococcus: presentation of a case in vitro studies that show a potentiating effect of erythromycin, chlortetracycline, and streptomycin on some strains of enterococci. | 1954 | AMA Arch Intern Med | pmid:13206462 |
| BUNN PA and COOK E | Treatment of pneumococcal pneumonia with erythromycin and carbomycin (magnamycin). | 1953 | AMA Arch Intern Med | pmid:13091455 |
| KIRBY WM et al. | Treatment of staphylococcic infections with erythromycin. | 1953 | AMA Arch Intern Med | pmid:13091463 |