erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

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Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

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What functions are associated with erythromycin?


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What lipids are associated with erythromycin?

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What genes are associated with erythromycin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

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Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Vanden Boom TJ Recent developments in the molecular genetics of the erythromycin-producing organism Saccharopolyspora erythraea. 2000 Adv. Appl. Microbiol. pmid:12876795
Vining LC Antibiotic tolerance in producer organisms. 1979 Adv. Appl. Microbiol. pmid:94753
Lechevalier HA Production of the same antibiotics by members of different genera of microorganisms. 1975 Adv. Appl. Microbiol. pmid:52998
Waksman SA Successes and failures in the search for antibiotics. 1969 Adv. Appl. Microbiol. pmid:4195044
Williams GJ and Thorson JS Natural product glycosyltransferases: properties and applications. 2009 Adv. Enzymol. Relat. Areas Mol. Biol. pmid:18990828
Garber NC et al. Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. 2011 Adv. Exp. Med. Biol. pmid:21618111
Yang YH et al. Opacity factor inhibition test for typing group A beta-haemolytic streptococcus strains and antibiotic susceptibility. 1997 Adv. Exp. Med. Biol. pmid:9331595
Jasir A and Schalén C Erythromycin resistance phenotypes in Swedish clinical isolates of group A streptococci. 1997 Adv. Exp. Med. Biol. pmid:9331689
Savoia D et al. Group A streptococci. Erythromycin resistance and penicillin tolerance. 1997 Adv. Exp. Med. Biol. pmid:9331690
Vicarini H et al. Analysis of regulatory region of ermAM genes in streptococci and enterococci highly resistant to macrolides and lincosamides. 1997 Adv. Exp. Med. Biol. pmid:9331702