erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Syphilis, Cardiovascular D013589 1 associated lipids
Chalazion D017043 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Trench Fever D014205 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Padovan J et al. Investigating the barriers to bioavailability of macrolide antibiotics in the rat. 2012 Eur J Drug Metab Pharmacokinet pmid:22113743
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Pollett S et al. Campylobacter antimicrobial resistance in Peru: a ten-year observational study. 2012 BMC Infect. Dis. pmid:22898609
Licona-Cassani C et al. Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. 2012 Antonie Van Leeuwenhoek pmid:22847261
Shimizu S et al. Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. 2012 J. Agric. Food Chem. pmid:22694300
Perry DM et al. Identification and characterization of protein phosphatase 2C activation by ceramide. 2012 J. Lipid Res. pmid:22615346
Deane AM et al. Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. 2012 Am. J. Clin. Nutr. pmid:22572649
Senhorinho GN et al. Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. 2012 Anaerobe pmid:22609780
Bidet P et al. Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:22610663
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Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
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Otsu K et al. Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. 2011 Pharmacology pmid:22116077
Nguyen NQ et al. Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance. 2011 Crit. Care Med. pmid:21297459
Thenmozhi R et al. Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. 2011 J. Basic Microbiol. pmid:21298675
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Mingoia M et al. Heterogeneity of Tn5253-like composite elements in clinical Streptococcus pneumoniae isolates. 2011 Antimicrob. Agents Chemother. pmid:21263055
Song W et al. Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. 2011 Int J Nanomedicine pmid:22228990
Ahmetagic A et al. Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. 2011 Plasmid pmid:21839110
Zhou L et al. Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. 2011 Vaccine pmid:21839135
Wu J et al. Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. 2011 Appl. Environ. Microbiol. pmid:21841022
Senthilkumaran S and Subramanian PT Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. 2011 Indian Pediatr pmid:22711153
Andini N and Nash KA Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. 2011 FEMS Microbiol. Lett. pmid:21718348
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Boghigian BA et al. Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. 2011 J. Ind. Microbiol. Biotechnol. pmid:21487833
Bonofiglio L et al. Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. 2011 Microb. Drug Resist. pmid:21128835
Zanoni RG et al. Occurrence of Helicobacter pullorum in turkeys. 2011 Vet. Microbiol. pmid:21144678
Altraif I et al. Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial. 2011 Gastrointest. Endosc. pmid:21145052
Bopp LH et al. Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages. 2011 Diagn. Microbiol. Infect. Dis. pmid:21146719
Pérez-Trallero E et al. In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates. 2011 Antimicrob. Agents Chemother. pmid:21343452
Filić D et al. Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. 2011 J Pharm Sci pmid:21394721
Manneck T et al. Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. 2011 Exp. Parasitol. pmid:20732321
van den Bosch S et al. Erythromycin to promote bedside placement of a self-propelled nasojejunal feeding tube in non-critically ill patients having pancreatitis: a randomized, double-blind, placebo-controlled study. 2011 Nutr Clin Pract pmid:21447772
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Sugawara A et al. Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. 2011 Bioorg. Med. Chem. Lett. pmid:21524580
Cong C et al. Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives. 2011 Eur J Med Chem pmid:21524827
Ando F et al. Synergic effects of β-estradiol and erythromycin on hERG currents. 2011 J. Membr. Biol. pmid:21484263
Flaman AS et al. The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. 2011 Toxicol. Appl. Pharmacol. pmid:21466820