erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Pleural Effusion, Malignant D016066 6 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Xerostomia D014987 6 associated lipids
Nocardia Infections D009617 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pericarditis D010493 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Whooping Cough D014917 6 associated lipids
Conjunctivitis D003231 7 associated lipids
Tachycardia D013610 7 associated lipids
Bone Resorption D001862 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Bronchiectasis D001987 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Bacteriuria D001437 7 associated lipids
Paresthesia D010292 7 associated lipids
Nausea D009325 7 associated lipids
Folliculitis D005499 7 associated lipids
Gonorrhea D006069 7 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Lipidoses D008064 7 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Leprosy D007918 8 associated lipids
Osteolysis D010014 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Arthralgia D018771 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Heart Diseases D006331 8 associated lipids
Otitis Externa D010032 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Constipation D003248 8 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Padovan J et al. Investigating the barriers to bioavailability of macrolide antibiotics in the rat. 2012 Eur J Drug Metab Pharmacokinet pmid:22113743
Mokhber-Dezfooli MR et al. Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. 2012 J. Dairy Sci. pmid:22981576
Walkey AJ and Wiener RS Macrolide antibiotics and survival in patients with acute lung injury. 2012 Chest pmid:22116799
Wills RH et al. Structural characterization of polyketides using high mass accuracy tandem mass spectrometry. 2012 Anal. Chem. pmid:22985101
Sugimoto T et al. Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. 2012 Bioorg. Med. Chem. pmid:22925450
Sugimoto T et al. Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. 2012 Bioorg. Med. Chem. Lett. pmid:22858102
Zou MX et al. Antimicrobial resistance and molecular epidemiological characteristics of clinical isolates of Staphylococcus aureus in Changsha area. 2012 Chin. Med. J. pmid:22882850
Dekio I Follicular spicules associated with Propionibacterium acnes with response to erythromycin: Lack of evidence for the species? 2012 J. Dermatol. pmid:22224953
März A et al. Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. 2012 Anal Bioanal Chem pmid:21822777
Zaknoon F et al. Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. 2012 Antimicrob. Agents Chemother. pmid:22751534
Gant CM et al. Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. 2012 Antimicrob. Agents Chemother. pmid:22751535
Kim J et al. Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. 2012 J. Microbiol. pmid:22752920
Arakawa K et al. The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. 2012 Chembiochem pmid:22761035
García-Pérez ME et al. Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. 2012 Food Chem pmid:22953840
De Sousa A and Kalra G Drug therapy of attention deficit hyperactivity disorder: current trends. 2012 Mens Sana Monogr pmid:22654382
Shore EM and Yudin MH Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. 2012 J Obstet Gynaecol Can pmid:22385665
Ullrich K et al. Neuroretinitis following bull ant sting. 2012 BMJ Case Rep pmid:22865803
Pollett S et al. Campylobacter antimicrobial resistance in Peru: a ten-year observational study. 2012 BMC Infect. Dis. pmid:22898609
Licona-Cassani C et al. Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. 2012 Antonie Van Leeuwenhoek pmid:22847261
Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. 2012 Prescrire Int pmid:22852287
Kim EY et al. The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. 2012 Acta Radiol pmid:22855416
Cetin M et al. Clarithromycin-Induced Long QT Syndrome: A Case Report. 2012 Case Rep Med pmid:22489247
Yuzawa S et al. Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. 2012 Biochemistry pmid:22509729
Shimizu S et al. Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. 2012 J. Agric. Food Chem. pmid:22694300
Perry DM et al. Identification and characterization of protein phosphatase 2C activation by ceramide. 2012 J. Lipid Res. pmid:22615346
Geddes BA and Oresnik IJ Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. 2012 Microbiology (Reading, Engl.) pmid:22609752
Noormohamed A and Fakhr MK Incidence and antimicrobial resistance profiling of Campylobacter in retail chicken livers and gizzards. 2012 Foodborne Pathog. Dis. pmid:22545960
Pinto TF et al. Tolerance to enteral nutrition therapy in traumatic brain injury patients. 2012 Brain Inj pmid:22571511
Deane AM et al. Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. 2012 Am. J. Clin. Nutr. pmid:22572649
Senhorinho GN et al. Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. 2012 Anaerobe pmid:22609780
Bidet P et al. Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:22610663
Rocco L et al. Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. 2012 Environ. Toxicol. pmid:21384490
Liu X et al. [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. 2012 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:23156807
Chen X et al. Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. 2012 Bioorg. Med. Chem. Lett. pmid:23122862
Li M et al. Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro. 2012 Int. Immunopharmacol. pmid:22265969
El Hafidi N et al. [Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis]. 2012 Rev. Neurol. (Paris) pmid:22244792
Tolosa L et al. Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. 2012 Toxicol. Sci. pmid:22331495
Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. 2012 Am Fam Physician pmid:22335221
Jordan PA and Miller SJ An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer. 2012 Angew. Chem. Int. Ed. Engl. pmid:22319027
Zhang H et al. Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. 2012 Jan-Feb Biotechnol. Prog. pmid:21905273
Pehr K Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. 2012 Jan-Feb J Cutan Med Surg pmid:22417996
Amatya A et al. Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. 2012 Jan-Mar Kathmandu Univ Med J (KUMJ) pmid:22971864
Kuhn M et al. Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. 2012 Jul-Aug Berl. Munch. Tierarztl. Wochenschr. pmid:22919930
Jiang RS et al. Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. 2012 Jul-Aug Am J Rhinol Allergy pmid:22801017
Kuehne SA and Minton NP ClosTron-mediated engineering of Clostridium. 2012 Jul-Aug Bioengineered pmid:22750794
Miguel AI et al. Pediatric ocular rosacea: 2 cases. 2012 Jul-Aug Eur J Ophthalmol pmid:22267454
Clementson B and Smidt AC Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. 2012 May-Jun Pediatr Dermatol pmid:22122785
Hapa A et al. Childhood pityriasis lichenoides and oral erythromycin. 2012 Nov-Dec Pediatr Dermatol pmid:22639857
Asai N et al. A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. 2012 Nov-Dec J Bras Pneumol pmid:23288130
Lian W et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. 2012 Oct-Dec Biosens Bioelectron pmid:22683249
Heelan K et al. Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. 2012 Sep-Oct Pediatr Dermatol pmid:21906149
Kuwahara T et al. Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. 2013 J. Cardiovasc. Electrophysiol. pmid:23551640
Lozada LE et al. Development of pyloric stenosis after a 4-day course of oral erythromycin. 2013 Pediatr Emerg Care pmid:23558266
Cuello-García CA et al. Treating BCG-induced disease in children. 2013 Cochrane Database Syst Rev pmid:23440826
Jersild Jespersen M et al. [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. 2013 Ugeskr. Laeg. pmid:23462037
Jiang M and Pfeifer BA Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. 2013 Metab. Eng. pmid:23747605
Xia Q et al. Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. 2013 BMC Microbiol. pmid:23767761
Kamal A et al. Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles. 2013 Bioorg. Med. Chem. Lett. pmid:24206766
Rallis E et al. Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. 2013 Acta Dermatovenerol Croat pmid:24183219
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Goh S et al. Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. 2013 MBio pmid:24255122
Horácio AN et al. The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. 2013 PLoS ONE pmid:24066064
Guo L et al. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. 2013 Toxicol. Sci. pmid:24052561
Guo MT et al. Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. 2013 Chemosphere pmid:24055024
Li YY et al. Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. 2013 BMC Genomics pmid:23902230
Link-Gelles R et al. Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. 2013 J. Infect. Dis. pmid:23852588
Cai G et al. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. 2013 J. Nat. Prod. pmid:24224794
Ong SJ et al. Staphylococcus aureus keratitis: a review of hospital cases. 2013 PLoS ONE pmid:24244625
Chroboczek T et al. Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. 2013 PLoS ONE pmid:24260092
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Fang J et al. Dissecting the function of a protruding loop in AcrB trimerization. 2013 J. Biomol. Struct. Dyn. pmid:22877148
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
Opdam FL et al. Breath tests to phenotype drug disposition in oncology. 2013 Clin Pharmacokinet pmid:23868281
Tsujimoto M et al. Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. 2013 Toxins (Basel) pmid:23965431
Petráčková D et al. Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. 2013 Microbiologyopen pmid:23996919
González-Abad MJ and Alonso-Sanz M [Incidence and susceptibility of Campylobacter jejuni in pediatric patients: involvement in bacteremia]. 2013 Rev Esp Quimioter pmid:23817644
Sanz-Rodríguez N et al. [Accuracy of Etest method to study Campylobacter spp. susceptibility to erythromycin, ciprofloxacin and tetracycline]. 2013 Rev Esp Quimioter pmid:23817649
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Parhi AK et al. Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. 2013 Bioorg. Med. Chem. Lett. pmid:23891185
Lee A Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? 2013 J. Gastrointest. Surg. pmid:23801519
Liu ZX et al. [Inhibition of methanogenium by erythromycin and its domestation]. 2013 Huan Jing Ke Xue pmid:23798140
Pasquini L et al. Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. 2013 Sci. Total Environ. pmid:23827359
Malinka W et al. Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. 2013 Bioorg. Med. Chem. pmid:23850103
Weber JM et al. Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. 2013 Appl. Microbiol. Biotechnol. pmid:23604533
Wittwer MB et al. Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. 2013 J. Med. Chem. pmid:23241029
Mavri A and Smole Možina S Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. 2013 Microb. Drug Resist. pmid:23289436
Lin KJ et al. Safety of macrolides during pregnancy. 2013 Am. J. Obstet. Gynecol. pmid:23254249
Sánchez Valenzuela A et al. Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. 2013 Foodborne Pathog. Dis. pmid:23259502
Sanad YM et al. Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. 2013 Foodborne Pathog. Dis. pmid:23259503
Haruna M et al. Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. 2013 J. Vet. Med. Sci. pmid:23220905
Javid FA et al. Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. 2013 Eur. J. Pharmacol. pmid:23201066
Goodman CD et al. Chemobiosynthesis of new antimalarial macrolides. 2013 Antimicrob. Agents Chemother. pmid:23208707
Li X et al. Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. 2013 Eur J Med Chem pmid:23229056
Nunez-Samudio V and Chesneau O Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. 2013 Res. Microbiol. pmid:23261969
Hisatsune J et al. Emergence of Staphylococcus aureus carrying multiple drug resistance genes on a plasmid encoding exfoliative toxin B. 2013 Antimicrob. Agents Chemother. pmid:24080652
Paterna A et al. Short communication: In vitro antimicrobial susceptibility of Mycoplasma agalactiae strains isolated from dairy goats. 2013 J. Dairy Sci. pmid:24035026
Metzler K et al. Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. 2013 J. Antimicrob. Chemother. pmid:23169894
Lasnier O et al. Two cases of corneal abrasions in children exposed to liquid detergent capsules. 2013 Can. J. Ophthalmol. pmid:23561618
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. 2013 Indian J. Med. Res. pmid:23563381
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400