erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stieler AL et al. | Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. | 2016 | Equine Vet. J. | pmid:26174202 |
Ulanovsky I et al. | Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. | 2016 | Isr. Med. Assoc. J. | pmid:28471562 |
Ray D et al. | Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India. | 2016 | BMC Infect. Dis. | pmid:27955635 |
Ma Y et al. | Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical isolates from a hospital in Shanghai, China. | 2016 | Front Med | pmid:27896620 |
Abreu AC et al. | Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. | 2016 | Biofouling | pmid:27643487 |
Jurado-Tarifa E et al. | Genetic diversity and antimicrobial resistance of Campylobacter and Salmonella strains isolated from decoys and raptors. | 2016 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:27638115 |
Hu Z et al. | Short-term performance of enhanced biological phosphorus removal (EBPR) system exposed to erythromycin (ERY) and oxytetracycline (OTC). | 2016 | Bioresour. Technol. | pmid:27631889 |
Benamrouche N et al. | Microbiological and molecular characterization of Corynebacterium diphtheriae isolated in Algeria between 1992 and 2015. | 2016 | Clin. Microbiol. Infect. | pmid:27585941 |
Kang CH and So JS | Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. | 2016 | Mar. Pollut. Bull. | pmid:27555484 |
Mushtaq A et al. | Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. | 2016 | Antimicrob. Agents Chemother. | pmid:27216060 |
Hong M et al. | Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. | 2016 | J. Biotechnol. | pmid:27215341 |
StaceviÄienÄ— I et al. | Antibiotic resistance of Streptococcus pneumoniae, isolated from nasopharynx of preschool children with acute respiratory tract infection in Lithuania. | 2016 | BMC Infect. Dis. | pmid:27206423 |
Tatiya-Aphiradee N et al. | In vivo antibacterial activity of Garcinia mangostana pericarp extract against methicillin-resistant Staphylococcus aureus in a mouse superficial skin infection model. | 2016 | Pharm Biol | pmid:27180784 |
He M et al. | Mechanism of synergy between SIPI-8294 and β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2016 | Lett. Appl. Microbiol. | pmid:27173151 |
Patel MB et al. | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. | 2016 | Bioorg. Med. Chem. | pmid:27166575 |
Taylor SJ et al. | A randomised controlled feasibility and proof-of-concept trial in delayed gastric emptying when metoclopramide fails: We should revisit nasointestinal feeding versus dual prokinetic treatment: Achieving goal nutrition in critical illness and delayed gastric emptying: Trial of nasointestinal feeding versus nasogastric feeding plus prokinetics. | 2016 | Clin Nutr ESPEN | pmid:28531392 |
Guo Q et al. | Controlling the feed rate of propanol to optimize erythromycin fermentation by on-line capacitance and oxygen uptake rate measurement. | 2016 | Bioprocess Biosyst Eng | pmid:26615414 |
Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
Poliquin V et al. | Preparedness for Implementing Change in Neonatal Ocular Prophylaxis Policies. | 2016 | J Obstet Gynaecol Can | pmid:26872748 |
Bouvet L et al. | Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series. | 2016 | Anesth. Analg. | pmid:26859878 |
Moltó-GarcÃa B et al. | Molecular characterization and antimicrobial susceptibility of hemolytic Streptococcus agalactiae from post-menopausal women. | 2016 | Maturitas | pmid:26857873 |
Sari E et al. | Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. | 2016 | Talanta | pmid:26838449 |
Magnussen MD et al. | Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. | 2016 | APMIS | pmid:26833774 |
Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
Zhou J et al. | A seventeen-year observation of the antimicrobial susceptibility of clinical Campylobacter jejuni and the molecular mechanisms of erythromycin-resistant isolates in Beijing, China. | 2016 | Int. J. Infect. Dis. | pmid:26594011 |
Ohbatake Y et al. | Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. | 2016 | Clin. Exp. Med. | pmid:26359244 |
Yuan SF et al. | Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology. | 2016 | Water Sci. Technol. | pmid:26901719 |
Loose LM et al. | Adolescent with respiratory impairments and short-lived fever. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130549 |
Liu J et al. | Preparation and characterization of erythromycin molecularly imprinted polymers based on distillation-precipitation polymerization. | 2015 | J Sep Sci | pmid:26118901 |
Fathollahipour S et al. | Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. | 2015 | J Biomed Mater Res A | pmid:26112829 |
Xing L et al. | ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. | 2015 | PLoS ONE | pmid:26107936 |
Dridi B et al. | Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. | 2015 | Antimicrob. Agents Chemother. | pmid:26100702 |
Czarnetzki C et al. | Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. | 2015 | JAMA Surg | pmid:26083537 |
Patti MG | Erythromycin Use Before Induction of General Endotracheal Anesthesia. | 2015 | JAMA Surg | pmid:26083012 |
Haenen CC et al. | [Rosacea fulminans in pregnancy]. | 2015 | Ned Tijdschr Geneeskd | pmid:26058762 |
Gagliotti C et al. | A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. | 2015 | Acta Paediatr. | pmid:26058421 |
Dermota U et al. | Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. | 2015 | Int. J. Med. Microbiol. | pmid:26055648 |
Drouet M et al. | Endothelial Cell Toxicity of Vancomycin Infusion Combined with Other Antibiotics. | 2015 | Antimicrob. Agents Chemother. | pmid:26055373 |
Reeves M et al. | Acute colonic pseudo-obstruction in pregnancy. | 2015 | ANZ J Surg | pmid:26044983 |
Vlakh EG et al. | Preparation and characterization of macroporous monoliths imprinted with erythromycin. | 2015 | J Sep Sci | pmid:26033867 |
Abukar AA et al. | Unusual cause of infective endocarditis in an elderly patient with a rare condition. | 2015 | BMJ Case Rep | pmid:25820110 |
Aydin S et al. | Combined effect of erythromycin, tetracycline and sulfamethoxazole on performance of anaerobic sequencing batch reactors. | 2015 | Bioresour. Technol. | pmid:25817031 |
Cui B et al. | Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical Staphylococcus capitis subspecies and a functional analysis of Ica proteins in S. capitis. | 2015 | J. Med. Microbiol. | pmid:25813821 |
Chew ML et al. | Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. | 2015 | Clin Drug Investig | pmid:25808394 |
Ericson JE et al. | Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. | 2015 | J. Pediatr. Gastroenterol. Nutr. | pmid:25806675 |
Aydin S et al. | Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. | 2015 | Water Res. | pmid:25792437 |
Zhu Y et al. | Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". | 2015 | Sci Rep | pmid:25791905 |
Wang P et al. | Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. | 2015 | PLoS ONE | pmid:25781346 |
Zhou Y et al. | Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. | 2015 | Talanta | pmid:25770599 |
Tojima I et al. | Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. | 2015 | Auris Nasus Larynx | pmid:25769240 |
Hao H et al. | Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. | 2015 | J. Appl. Microbiol. | pmid:25766481 |
Nonaka L et al. | Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. | 2015 | Lett. Appl. Microbiol. | pmid:25765542 |
Mills RO et al. | Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. | 2015 | Infect Dis (Lond) | pmid:25761718 |
Hersch M et al. | Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. | 2015 | J Crit Care | pmid:25746849 |
Lee S et al. | Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. | 2015 | J. Microbiol. | pmid:25740377 |
Lin X et al. | Macrolides for diffuse panbronchiolitis. | 2015 | Cochrane Database Syst Rev | pmid:25618845 |
Sakata H | The change of macrolide resistance rates in group A Streptococcus isolates from children between 2002 and 2013 in Asahikawa city. | 2015 | J. Infect. Chemother. | pmid:25618777 |
Johnson AC et al. | Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. | 2015 | Sci. Total Environ. | pmid:25617699 |
Wang P et al. | Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. | 2015 | Microb. Cell Fact. | pmid:25612661 |
Chiaverini C et al. | Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. | 2015 | Br. J. Dermatol. | pmid:25601422 |
Li Z et al. | New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2015 | Lett. Appl. Microbiol. | pmid:25588530 |
Gardiner SJ et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2015 | Cochrane Database Syst Rev | pmid:25566754 |
Azadegan A et al. | Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. | 2015 | Ann Lab Med | pmid:25553281 |
Wu H et al. | Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25549616 |
Cetecioglu Z et al. | Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. | 2015 | Chemosphere | pmid:25542637 |
Novak I and KovaÄ B | Electronic structure of antibiotic erythromycin. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25528514 |
Ansari NN et al. | A randomized clinical trial comparing pulsed ultrasound and erythromycin phonophoresis in the treatment of patients with chronic rhinosinusitis. | 2015 | Physiother Theory Pract | pmid:25495769 |
Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
MarÃn M et al. | Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. | 2015 | Antimicrob. Agents Chemother. | pmid:25385106 |
Igbinosa IH | Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. | 2015 | Trop Anim Health Prod | pmid:25348646 |
Wang Z et al. | Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. | 2015 | Food Chem | pmid:25308648 |
Galvidis I et al. | Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. | 2015 | Anal. Biochem. | pmid:25256165 |
Siekmeier R et al. | Inhalation of macrolides: a novel approach to treatment of pulmonary infections. | 2015 | Adv. Exp. Med. Biol. | pmid:25252902 |
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Hawkins PA et al. | Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. | 2015 | Microb. Drug Resist. | pmid:25115711 |
Vallianou N et al. | Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. | 2015 | J Chemother | pmid:25112954 |
Kempe H et al. | Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. | 2015 | Pharm. Res. | pmid:25103333 |
Chen Y et al. | The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. | 2015 | Bioprocess Biosyst Eng | pmid:25042891 |
Yang J et al. | Improving heterologous polyketide production in Escherichia coli by transporter engineering. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26062534 |
Mazur CS et al. | P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. | 2015 | Toxicol. Lett. | pmid:25268938 |
Muralidharan V and Striepen B | Teaching old drugs new tricks to stop malaria invasion in its tracks. | 2015 | BMC Biol. | pmid:26349580 |
Song LY et al. | Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. | 2015 | Antimicrob. Agents Chemother. | pmid:26711761 |
Pavlova A and Gumbart JC | Parametrization of macrolide antibiotics using the force field toolkit. | 2015 | J Comput Chem | pmid:26280362 |
Feng T et al. | Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. | 2015 | J. Comput. Aided Mol. Des. | pmid:26564143 |
Aydın S et al. | Inhibitory effect of erythromycin, tetracycline and sulfamethoxazole antibiotics on anaerobic treatment of a pharmaceutical wastewater. | 2015 | Water Sci. Technol. | pmid:26038926 |
Daghighi S et al. | Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. | 2015 | Int. J. Antimicrob. Agents | pmid:26526893 |
Bravo-Rodriguez K et al. | Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. | 2015 | Chem. Biol. | pmid:26526102 |
Bérard A et al. | Use of macrolides during pregnancy and the risk of birth defects: a population-based study. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26513406 |
Fedashchin A et al. | Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. | 2015 | FEMS Microbiol. Lett. | pmid:26468041 |
Lu H et al. | High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. | 2015 | Emerg Microbes Infect | pmid:26038763 |
Arinto-Garcia R et al. | Comparing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Phenotypic and Molecular Methods for Identification of Species within the Streptococcus anginosus Group. | 2015 | J. Clin. Microbiol. | pmid:26354817 |
Han X et al. | Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. | 2015 | Bioorg. Med. Chem. | pmid:26349628 |
Wróblewska M and Winnicka K | The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. | 2015 | Int J Mol Sci | pmid:26343637 |
Bolukaoto JY et al. | Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. | 2015 | BMC Res Notes | pmid:26289147 |
Liao CH et al. | DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26272095 |
Å mitran A et al. | Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. | 2015 | Mem. Inst. Oswaldo Cruz | pmid:26270594 |
Wang YL et al. | Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. | 2015 | Foodborne Pathog. Dis. | pmid:26258263 |
Prohl A et al. | Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. | 2015 | PLoS ONE | pmid:25768665 |
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