erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Manzo L et al. | [Effects of phenobarbital on the distribution of erythromycin and erythromycin aspartate in the rat]. | 1976 Jan-Jun | G Ital Chemioter | pmid:1029694 |
| Baggot JD and Gingerich DA | Pharmacokinetic interpretation of erythromycin and tylosin activity in serum after intravenous administration of a single dose to cows. | 1976 | Res. Vet. Sci. | pmid:1030820 |
| Di Nucci A et al. | [Metabolism of erythromycin and erythromycin aspartate in the microsomal fraction of the rat liver]. | 1976 | Boll. Soc. Ital. Biol. Sper. | pmid:1030960 |
| Fisher AA | The safety of topical erythromycin. | 1976 | Contact Derm. | pmid:1032121 |
| van Ketel WG | Immediate- and delayed-type allergy to erythromycin. | 1976 | Contact Derm. | pmid:1032135 |
| York MK et al. | Characterization of antimicrobial resistance in Streptococcus pyogenes isolates from the San Francisco Bay area of northern California. | 1999 | J. Clin. Microbiol. | pmid:10325315 |
| Cazzola M et al. | Comparative study of dirithromycin and azithromycin in the treatment of acute bacterial exacerbations of chronic bronchitis. | 1999 | J Chemother | pmid:10326742 |
| Bojarska-Dahlig H et al. | L-aspartate of erythromycin A cyclic 11,12-carbonate, a new semisynthetic erythromycin derivative. | 1976 | J. Antibiot. | pmid:1033178 |
| Wu SW et al. | The Staphylococcus aureus transposon Tn551: complete nucleotide sequence and transcriptional analysis of the expression of the erythromycin resistance gene. | 1999 | Microb. Drug Resist. | pmid:10332716 |
| Jones KL et al. | Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects. | 1999 | Diabetes Care | pmid:10333955 |
| Dornbusch K et al. | Postantibiotic effect and postantibiotic sub-mic effect of dirithromycin and erythromycin against respiratory tract pathogenic bacteria. | 1999 | APMIS | pmid:10335955 |
| Mertens PR et al. | Long-term extracorporeal bilirubin elimination: A case report on cascade resin plasmaperfusion. | 1998 | Blood Purif. | pmid:10343081 |
| Levert H et al. | Time and concentration dependent influence of dirithromycin on neutrophils oxidative burst. | 1999 | J. Antibiot. | pmid:10344566 |
| Parsons IC et al. | Structural elucidation of a novel erythromycin, 13-cyclopentyl-13-desethyl-erythromycin B, from a recombinant Saccharopolyspora erythraea strain, NRRL 2338 pIG/1. | 1999 | J. Antibiot. | pmid:10344576 |
| Mikami Y et al. | Production of erythromycin E by pathogenic Nocardia brasiliensis. | 1999 | J. Antibiot. | pmid:10344579 |
| Dujovne CA | Experimental investigations on the different hepatotoxic potential of erythromycin derivatives. | 1976 | Med Chir Dig | pmid:1034861 |
| Champney WS and Tober CL | Molecular investigation of the postantibiotic effects of clarithromycin and erythromycin on Staphylococcus aureus cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10348746 |
| Roberts MC et al. | Erythromycin-resistant Neisseria gonorrhoeae and oral commensal Neisseria spp. carry known rRNA methylase genes. | 1999 | Antimicrob. Agents Chemother. | pmid:10348754 |
| Greiver M | Practice tips. Incorporating a rapid group A streptococcus assay with the sore throat score. | 1999 | Can Fam Physician | pmid:10349060 |
| Simon MW | Treatment of acute sinusitis in childhood with ceftibuten. | 1999 | Clin Pediatr (Phila) | pmid:10349523 |