erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Yu I et al. | [The effects of the erythromycin on the production of r-glutamylcys glutamylcysteine synthetase and glutathione in the bronchial epithelial cell]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186628 |
Jia P et al. | [Regulative effect of electroacupuncture of different frequencies on derangement of gastric electric rhythm in rabbits]. | 2006 | Zhongguo Zhen Jiu | pmid:17165505 |
Guan Y et al. | [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23724685 |
Guan Y et al. | [Preliminary study of effects of andrographolide on Staphylococcus epidermidis biofilms]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23126203 |
Tang J and Li Y | [Effect of erythromycin on the expression of apoptotic gene on eosinophils in nasal polyps in vitro]. | 2003 | Zhonghua Er Bi Yan Hou Ke Za Zhi | pmid:15040110 |
Tang J et al. | [Effect of erythromycin on apoptosis of eosinophils in nasal polyps in vitro]. | 2002 | Zhonghua Er Bi Yan Hou Ke Za Zhi | pmid:12768725 |
Xu SN et al. | [Effect of erythromycin on apoptosis of epithelial cell in nasal polyps]. | 2006 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:17007374 |
Hua CZ et al. | [Antibiotics-resistance pattern and genetic type of Streptococcus pneumoniae isolated from children in Hangzhou]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:14990098 |
He JX et al. | [Demonstration of a mechanism of anti-inflammatory effect of erythromycin on allergic airway inflammation in rat]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:15833193 |
Hua CZ et al. | [Drug-resistance of staphylococcus aureus and detection of mecA gene in all strains isolated from children in Hangzhou]. | 2006 | Zhonghua Er Ke Za Zhi | pmid:16780714 |