erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Manzo L et al. | [Effects of phenobarbital on the distribution of erythromycin and erythromycin aspartate in the rat]. | 1976 Jan-Jun | G Ital Chemioter | pmid:1029694 |
Baggot JD and Gingerich DA | Pharmacokinetic interpretation of erythromycin and tylosin activity in serum after intravenous administration of a single dose to cows. | 1976 | Res. Vet. Sci. | pmid:1030820 |
Di Nucci A et al. | [Metabolism of erythromycin and erythromycin aspartate in the microsomal fraction of the rat liver]. | 1976 | Boll. Soc. Ital. Biol. Sper. | pmid:1030960 |
Fisher AA | The safety of topical erythromycin. | 1976 | Contact Derm. | pmid:1032121 |
van Ketel WG | Immediate- and delayed-type allergy to erythromycin. | 1976 | Contact Derm. | pmid:1032135 |
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Cazzola M et al. | Comparative study of dirithromycin and azithromycin in the treatment of acute bacterial exacerbations of chronic bronchitis. | 1999 | J Chemother | pmid:10326742 |
Bojarska-Dahlig H et al. | L-aspartate of erythromycin A cyclic 11,12-carbonate, a new semisynthetic erythromycin derivative. | 1976 | J. Antibiot. | pmid:1033178 |
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Jones KL et al. | Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects. | 1999 | Diabetes Care | pmid:10333955 |
Dornbusch K et al. | Postantibiotic effect and postantibiotic sub-mic effect of dirithromycin and erythromycin against respiratory tract pathogenic bacteria. | 1999 | APMIS | pmid:10335955 |
Mertens PR et al. | Long-term extracorporeal bilirubin elimination: A case report on cascade resin plasmaperfusion. | 1998 | Blood Purif. | pmid:10343081 |
Levert H et al. | Time and concentration dependent influence of dirithromycin on neutrophils oxidative burst. | 1999 | J. Antibiot. | pmid:10344566 |
Parsons IC et al. | Structural elucidation of a novel erythromycin, 13-cyclopentyl-13-desethyl-erythromycin B, from a recombinant Saccharopolyspora erythraea strain, NRRL 2338 pIG/1. | 1999 | J. Antibiot. | pmid:10344576 |
Mikami Y et al. | Production of erythromycin E by pathogenic Nocardia brasiliensis. | 1999 | J. Antibiot. | pmid:10344579 |
Dujovne CA | Experimental investigations on the different hepatotoxic potential of erythromycin derivatives. | 1976 | Med Chir Dig | pmid:1034861 |
Champney WS and Tober CL | Molecular investigation of the postantibiotic effects of clarithromycin and erythromycin on Staphylococcus aureus cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10348746 |
Roberts MC et al. | Erythromycin-resistant Neisseria gonorrhoeae and oral commensal Neisseria spp. carry known rRNA methylase genes. | 1999 | Antimicrob. Agents Chemother. | pmid:10348754 |
Greiver M | Practice tips. Incorporating a rapid group A streptococcus assay with the sore throat score. | 1999 | Can Fam Physician | pmid:10349060 |
Simon MW | Treatment of acute sinusitis in childhood with ceftibuten. | 1999 | Clin Pediatr (Phila) | pmid:10349523 |
Wasilewski MM et al. | Five-day dirithromycin therapy is as effective as seven-day erythromycin therapy for acute exacerbations of chronic bronchitis. | 1999 | J. Antimicrob. Chemother. | pmid:10350384 |
Rosato A et al. | Inducible or constitutive expression of resistance in clinical isolates of streptococci and enterococci cross-resistant to erythromycin and lincomycin. | 1999 | J. Antimicrob. Chemother. | pmid:10350387 |
Fearfield LA and Staughton RC | Severe vulval apocrine acne successfully treated with prednisolone and isotretinoin. | 1999 | Clin. Exp. Dermatol. | pmid:10354177 |
Erickson PR and Herzberg MC | Emergence of antibiotic resistant Streptococcus sanguis in dental plaque of children after frequent antibiotic therapy. | 1999 May-Jun | Pediatr Dent | pmid:10355009 |
Leal AL and Castañeda E | [Susceptibility to antimicrobial agents in isolates from invasive Streptococcus pneumoniae in Colombia]. | 1999 | Rev. Panam. Salud Publica | pmid:10355313 |
Kalima P et al. | Epidemiology of Streptococcus pneumoniae infections at the Edinburgh City Hospital: 1980-95. | 1999 | Epidemiol. Infect. | pmid:10355789 |
Janovska D et al. | Administration of antibiotics in combination. Determination of antibacterial effectivity of blood serum and urine after simultaneous administration of macrolides and tetracyclines. | 1976 | J Hyg Epidemiol Microbiol Immunol | pmid:1035924 |
Irokawa T et al. | Cholinomimetic action of macrolide antibiotics on airway gland electrolyte secretion. | 1999 | Am. J. Physiol. | pmid:10362719 |
Viñado B et al. | [Resistance to erythromycin in strains of Streptococcus pyogenes isolated in the province of Barcelona]. | 1999 | Med Clin (Barc) | pmid:10363246 |
Tamayo M et al. | Dissemination of a chloramphenicol- and tetracycline-resistant but penicillin-susceptible invasive clone of serotype 5 Streptococcus pneumoniae in Colombia. | 1999 | J. Clin. Microbiol. | pmid:10364609 |
Schulte W et al. | [Diffuse panbronchiolitis. A rare differential diagnosis of chronic obstructive lung disease]. | 1999 | Dtsch. Med. Wochenschr. | pmid:10365176 |
Petrakis IE et al. | Hyperglycaemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in idiopathic and diabetic gastroparesis. | 1999 | Scand. J. Gastroenterol. | pmid:10365900 |
Cilostazol for intermittent claudication. | 1999 | Med Lett Drugs Ther | pmid:10368703 | |
Gregory ST and Dahlberg AE | Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA. | 1999 | J. Mol. Biol. | pmid:10369764 |
Arum ES and Jacobs NF | Nongonococcal urethritis. | 1976 | Cutis | pmid:1037101 |
Hume EB et al. | Clarithromycin for experimental Staphylococcus aureus keratitis. | 1999 | Curr. Eye Res. | pmid:10372997 |
Gao W et al. | [Analysis of 9 cases of pulmonary tuberculosis complicated with legionnaires disease]. | 1997 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:10374448 |
Taege AJ | Listeriosis: recognizing it, treating it, preventing it. | 1999 | Cleve Clin J Med | pmid:10375847 |
Alvarez-Elcoro S and Enzler MJ | The macrolides: erythromycin, clarithromycin, and azithromycin. | 1999 | Mayo Clin. Proc. | pmid:10377939 |
Griga T et al. | [Effect of stomach motility on measuring stomach permeability with saccharose in vivo]. | 1999 | Z Gastroenterol | pmid:10378362 |
Hägg S et al. | Absence of interaction between erythromycin and a single dose of clozapine. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10379638 |
Huber R et al. | Increase of cellular hypoxic tolerance by erythromycin and other antibiotics. | 1999 | Neuroreport | pmid:10380977 |
Feighner SD et al. | Receptor for motilin identified in the human gastrointestinal system. | 1999 | Science | pmid:10381885 |
Ruckdeschel G and Dalhoff A | The in-vitro activity of moxifloxacin against Legionella species and the effects of medium on susceptibility test results. | 1999 | J. Antimicrob. Chemother. | pmid:10382872 |
Nishijima T et al. | Distribution of mefE and ermB genes in macrolide-resistant strains of Streptococcus pneumoniae and their variable susceptibility to various antibiotics. | 1999 | J. Antimicrob. Chemother. | pmid:10382884 |
Bébéar CM et al. | In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas. | 1999 | J. Antimicrob. Chemother. | pmid:10382895 |
McConnell SA et al. | Lack of effect of dirithromycin on theophylline pharmacokinetics in healthy volunteers. | 1999 | J. Antimicrob. Chemother. | pmid:10382900 |
Tzelepi E et al. | Erythromycin resistance amongst group A beta-haemolytic streptococci isolated in a paediatric hospital in Athens, Greece. | 1999 | J. Antimicrob. Chemother. | pmid:10382903 |
Valisena S et al. | Molecular typing of erythromycin-resistant streptococcus pyogenes strains with the M phenotype isolated in Italy. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10385014 |
Francis GS | Cardiac complications in the intensive care unit. | 1999 | Clin. Chest Med. | pmid:10386256 |