erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
Fessler AT et al. | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:20876371 |
Abarzúa F et al. | [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. | 2011 | Rev Chilena Infectol | pmid:22052397 |
Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
Tachecà I et al. | Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. | 2011 | Neuro Endocrinol. Lett. | pmid:22167215 |
Lam HS and Ng PC | Use of prokinetics in the preterm infant. | 2011 | Curr. Opin. Pediatr. | pmid:21178622 |
Ma S et al. | Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. | 2011 | Eur J Med Chem | pmid:21159410 |
Mak PJ et al. | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. | 2011 | J. Am. Chem. Soc. | pmid:21207936 |
Ren GW et al. | Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. | 2011 | Foodborne Pathog. Dis. | pmid:21166562 |
Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
Sonnevend à et al. | Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. | 2011 | Scand. J. Infect. Dis. | pmid:21905953 |
Torra S et al. | Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). | 2011 | Int J Obes (Lond) | pmid:20938444 |
Li MJ et al. | High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. | 2011 | Analyst | pmid:20944848 |
Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
Chen I et al. | Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. | 2011 | J. Clin. Microbiol. | pmid:21068284 |
Bilk S et al. | Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. | 2011 | Vet. Microbiol. | pmid:21131144 |
Zou X et al. | An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. | 2011 | Bioresour. Technol. | pmid:21134745 |
Jorgensen JH et al. | Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. | 2011 | J. Clin. Microbiol. | pmid:21697321 |
Wenzel F et al. | Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). | 2011 | Clin. Hemorheol. Microcirc. | pmid:22214710 |
Mansi Y et al. | Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants. | 2011 | Neonatology | pmid:21701222 |
Amarir-Bouhram J et al. | Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. | 2011 | PLoS ONE | pmid:22194937 |
Ng PC | Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). | 2011 | Neonatology | pmid:21701224 |
Sarig H et al. | Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. | 2011 | FASEB J. | pmid:21676947 |
Shingate BB et al. | Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. | 2011 | Eur J Med Chem | pmid:21664730 |
Hoa PT et al. | Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. | 2011 | Sci. Total Environ. | pmid:21669325 |
Kataoka M et al. | Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. | 2011 | Eur J Pharm Sci | pmid:21963456 |
Hernández y Ballinas A et al. | [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. | 2011 | Ginecol Obstet Mex | pmid:21966834 |
Gupta R et al. | A 14-year-old with rectal bleeding and abdominal pain. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21970991 |
Heath AP et al. | An algorithm for efficient identification of branched metabolic pathways. | 2011 | J. Comput. Biol. | pmid:21999288 |
Zhang Z et al. | Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21498135 |
Del Grosso M et al. | Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. | 2011 | Antimicrob. Agents Chemother. | pmid:21502613 |
Loreto ES et al. | In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. | 2011 | Antimicrob. Agents Chemother. | pmid:21537028 |
Nakamura PA et al. | Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. | 2011 | Mem. Inst. Oswaldo Cruz | pmid:21537668 |
Shaala LA et al. | Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. | 2011 | J. Nat. Prod. | pmid:21542602 |
Chen HX et al. | [Compound erythromycin sustained release preparation and its in vitro release]. | 2011 | Yao Xue Xue Bao | pmid:22260035 |
Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |
Park HH et al. | The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. | 2010 Sep-Oct | Am J Rhinol Allergy | pmid:21244734 |
Luiz DB et al. | Identification of degradation products of erythromycin A arising from ozone and advanced oxidation process treatment. | 2010 Sep-Oct | Water Environ. Res. | pmid:20942335 |
Al-Talib HI et al. | Methicillin-resistant Staphylococcus aureus nosocomial infection trends in Hospital Universiti Sains Malaysia during 2002-2007. | 2010 Sep-Oct | Ann Saudi Med | pmid:20697171 |
Murray MA et al. | Ocular bacillary angiomatosis in an immunocompromised man. | 2010 Sep-Oct | Ophthal Plast Reconstr Surg | pmid:20683276 |
Taneja N et al. | Emergence of tetracycline resistance in Vibrio cholerae O1 biotype El Tor serotype Ogawa from north India. | 2010 Oct-Dec | Indian J Pathol Microbiol | pmid:21045454 |
Dutil M | Benzoyl peroxide: enhancing antibiotic efficacy in acne management. | 2010 Nov-Dec | Skin Therapy Lett. | pmid:21076800 |
Levin TT et al. | Case report: delirium due to a diltiazem-fentanyl CYP3A4 drug interaction. | 2010 Nov-Dec | Gen Hosp Psychiatry | pmid:21112467 |
Bornstein E et al. | Photodamage to multidrug-resistant gram-positive and gram-negative bacteria by 870 nm/930 nm light potentiates erythromycin, tetracycline and ciprofloxacin. | 2010 May-Jun | Photochem. Photobiol. | pmid:20408973 |
Taylor SJ et al. | Treating delayed gastric emptying in critical illness: metoclopramide, erythromycin, and bedside (cortrak) nasointestinal tube placement. | 2010 May-Jun | JPEN J Parenter Enteral Nutr | pmid:20467010 |
Zhang LX et al. | Febrile ulceronecrotic Mucha-Habermann's disease with pulmonary involvement. | 2010 May-Jun | Pediatr Dermatol | pmid:20609148 |
Vorster M et al. | Erythromycin as an alternative to reduce interfering extra-cardiac activity in myocardial perfusion imaging. | 2010 May-Jun | Cardiovasc J Afr | pmid:20532452 |
Poulard F et al. | Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: a prospective before-after study. | 2010 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:19861528 |
Torrelo A et al. | Extensive comedonal and cystic acne in Patau syndrome. | 2010 Mar-Apr | Pediatr Dermatol | pmid:20537076 |
Armangil D et al. | Maternal pertussis is hazardous for a newborn: a case report. | 2010 Mar-Apr | Turk. J. Pediatr. | pmid:20560262 |
Tempera G et al. | In vitro activity of cefditoren versus other antibiotics against S. pneumoniae clinical strains isolated in Italy. | 2010 Jul-Sep | Int J Immunopathol Pharmacol | pmid:20943054 |
Pal N et al. | Detection of inducible clindamycin resistance among Staphylococcal isolates from different clinical specimens in western India. | 2010 Jul-Sep | J Postgrad Med | pmid:20739762 |
Darling EK and McDonald H | A meta-analysis of the efficacy of ocular prophylactic agents used for the prevention of gonococcal and chlamydial ophthalmia neonatorum. | 2010 Jul-Aug | J Midwifery Womens Health | pmid:20630358 |
Smith G | Differential diagnosis of red eye. | 2010 Jul-Aug | Pediatr Nurs | pmid:20860262 |
Dorobăţ OM et al. | [Antibiotic resistance of Gram-positive cocci isolated in 2008]. | 2010 Apr-Jun | Bacteriol Virusol Parazitol Epidemiol | pmid:21553473 |
Pană M et al. | [Study of Streptococcus pneumoniae strains resistant to antibiotics analyzed at "Cantacuzino" NIRDMI during 2006-2008]. | 2010 Apr-Jun | Bacteriol Virusol Parazitol Epidemiol | pmid:21553474 |
Nica M et al. | [Bacterial strains isolated from systemic infections and reported for evaluation and antibiotic resistance surveillance by the "Dr. Victor BabeÅŸ" Clinical Hospital for Infectious and Tropical Diseases, Bucharest]. | 2010 Apr-Jun | Bacteriol Virusol Parazitol Epidemiol | pmid:21553481 |
Namikawa H et al. | Effect of erythromycin A and its new derivative EM201 on type I collagen production by cultured dermal fibroblasts. | 2010 | Arch. Dermatol. Res. | pmid:19578864 |
Demirkan A et al. | Endotoxin level in ischemia-reperfusion injury in rats: effect of glutamine pretreatment on endotoxin levels and gut morphology. | 2010 | Nutrition | pmid:19596185 |
Liu Y et al. | 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. | 2010 | Bioorg. Med. Chem. | pmid:20869254 |
Leszczyńska K et al. | Modulation of exogenous antibiotic activity by host cathelicidin LL-37. | 2010 | APMIS | pmid:20955455 |
Atkins JL et al. | Enhancement of antimicrobial activity by synthetic ion channel synergy. | 2010 | Chem. Commun. (Camb.) | pmid:20931142 |
Keurulainen L et al. | Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae. | 2010 | J. Med. Chem. | pmid:20932010 |
Aguilera R C et al. | [Antimicrobial susceptibility, capsular serotypes and clonal relationship of invasive streptococcus pneumoniae isolates in adult population of the Bio-Bio region, Chile. 2005-2006]. | 2010 | Rev Chilena Infectol | pmid:21186502 |
Cetin ES et al. | Distribution of genes encoding resistance to macrolides, lincosamides and streptogramins among clinical staphylococcal isolates in a Turkish university hospital. | 2010 | J Microbiol Immunol Infect | pmid:21195981 |
Pazoki-Toroudi H et al. | Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. | 2010 | J Dermatolog Treat | pmid:20394495 |
Stringer E et al. | Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth. | 2010 | S. Afr. Med. J. | pmid:20429491 |
Tokuda A et al. | Effects of macrolides on antigen-induced increases in cough reflex sensitivity in guinea pigs. | 2010 | Pulm Pharmacol Ther | pmid:19835975 |
Padilla E et al. | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. | 2010 | Antimicrob. Agents Chemother. | pmid:19858254 |
Glass SK et al. | Canadian province-level risk factor analysis of macrolide consumption patterns (2000-2006). | 2010 | J. Antimicrob. Chemother. | pmid:19864333 |
Goetting-Minesky MP and Fenno JC | A simplified erythromycin resistance cassette for Treponema denticola mutagenesis. | 2010 | J. Microbiol. Methods | pmid:20691222 |
Mazzoncini JP et al. | Human metapneumovirus: an emerging respiratory pathogen. | 2010 | J Emerg Med | pmid:18584996 |
Banche G et al. | Synergistic effect of erythromycin on polymorphonuclear cell antibacterial activity against erythromycin-resistant phenotypes of Streptococcus pyogenes. | 2010 | Int. J. Antimicrob. Agents | pmid:20692129 |
Shi HY et al. | Effects of erythromycin on voriconazole pharmacokinetics and association with CYP2C19 polymorphism. | 2010 | Eur. J. Clin. Pharmacol. | pmid:20669013 |
Accinelli C et al. | Removal of oseltamivir (Tamiflu) and other selected pharmaceuticals from wastewater using a granular bioplastic formulation entrapping propagules of Phanerochaete chrysosporium. | 2010 | Chemosphere | pmid:20673959 |
Miyashita N et al. | Macrolide-resistant Mycoplasma pneumoniae in adults with community-acquired pneumonia. | 2010 | Int. J. Antimicrob. Agents | pmid:20674283 |
Horner P | Chlamydia (uncomplicated, genital). | 2010 | BMJ Clin Evid | pmid:21718568 |
Ren W et al. | Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis. | 2010 | Inflamm. Res. | pmid:20607583 |
Ortiz-Pérez A et al. | High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. | 2010 | Microb. Drug Resist. | pmid:20624090 |
Dundar D et al. | Macrolide and tetracycline resistance and emm type distribution of Streptococcus pyogenes isolates recovered from Turkish patients. | 2010 | Microb. Drug Resist. | pmid:20624096 |
Biedenbach DJ et al. | Determination of CEM-101 activity tested against clinical isolates of Neisseria meningitidis from a worldwide collection. | 2010 | Antimicrob. Agents Chemother. | pmid:20625152 |
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Pavlović D et al. | Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials. | 2010 | Bioorg. Med. Chem. | pmid:21055953 |
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Kana BD et al. | Depletion of resuscitation-promoting factors has limited impact on the drug susceptibility of Mycobacterium tuberculosis. | 2010 | J. Antimicrob. Chemother. | pmid:20542905 |
Kadlec K and Schwarz S | Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. | 2010 | Antimicrob. Agents Chemother. | pmid:20498309 |
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Zähner D et al. | Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae. | 2010 | Antimicrob. Agents Chemother. | pmid:20498319 |
Morrow BJ et al. | In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. | 2010 | Antimicrob. Agents Chemother. | pmid:20176911 |
Fraser RJ and Bryant L | Current and future therapeutic prokinetic therapy to improve enteral feed intolerance in the ICU patient. | 2010 | Nutr Clin Pract | pmid:20130155 |
Cocco G and Gasparyan AY | Myocardial ischemia in Wegener's granulomatosis: coronary atherosclerosis versus vasculitis. | 2010 | Open Cardiovasc Med J | pmid:20360980 |
Auerbach T et al. | The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080686 |
Krenauer A et al. | EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report. | 2010 | Diagn Pathol | pmid:20356360 |
Sun H et al. | Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease. | 2010 | Clin. Pharmacol. Ther. | pmid:20090676 |
Cousens S et al. | Antibiotics for pre-term pre-labour rupture of membranes: prevention of neonatal deaths due to complications of pre-term birth and infection. | 2010 | Int J Epidemiol | pmid:20348116 |
Devirgiliis C et al. | Identification of tetracycline- and erythromycin-resistant Gram-positive cocci within the fermenting microflora of an Italian dairy food product. | 2010 | J. Appl. Microbiol. | pmid:20092542 |
Wang X et al. | Bupropion metabolism by human placenta. | 2010 | Biochem. Pharmacol. | pmid:20109440 |
Lu NF et al. | [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]. | 2010 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:20092709 |