erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ingham E | The effects of tetracyclines and erythromycin on complement activation in vitro. | 1990 | Acta Derm. Venereol. | pmid:1981435 |
Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
Mills OH and Kligman AM | Treatment of acne vulgaris with topically applied erythromycin and tretinoin. | 1978 | Acta Derm. Venereol. | pmid:83088 |
Bernstein JE and Shalita AR | Effects of topical erythromycin on aerobic and anaerobic surface flora. | 1980 | Acta Derm. Venereol. | pmid:6162344 |
Karvonen SL et al. | Systemic corticosteroid and isotretinoin treatment in cystic acne. | 1993 | Acta Derm. Venereol. | pmid:7906462 |
Mills O et al. | Bacterial resistance and therapeutic outcome following three months of topical acne therapy with 2% erythromycin gel versus its vehicle. | 2002 | Acta Derm. Venereol. | pmid:12361129 |
Bowyer A and McColl I | Erythrasma and pruritus ani. | 1971 | Acta Derm. Venereol. | pmid:4109425 |
Gudjónsson H | Experiments to induce febrile Jarisch-Herxheimer reaction in syphilitic rabbits with penicillin and erythromycin. | 1972 | Acta Derm. Venereol. | pmid:4118397 |
Worm AM | Roxithromycin and erythromycin in chlamydia-negative non-gonococcal urethritis. | 1990 | Acta Derm. Venereol. | pmid:1972850 |
Rajka G | Treatment of gonorrhoea patients with intolerance to penicillin. | 1968 | Acta Derm. Venereol. | pmid:4177580 |