erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Pancreatitis D010195 10 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Paresthesia D010292 7 associated lipids
Parotitis D010309 4 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Periapical Diseases D010483 4 associated lipids
Pericarditis D010493 6 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Pericoronitis D010497 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Periodontitis D010518 22 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Pityriasis D010915 3 associated lipids
Pleural Diseases D010995 4 associated lipids
Pleural Effusion D010996 3 associated lipids
Pleurisy D010998 20 associated lipids
Pleuropneumonia D011001 3 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Pneumonia D011014 10 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Porphyrias D011164 2 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
Prolapse D011391 1 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Prostatitis D011472 5 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Psoriasis D011565 47 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Pulmonary Emphysema D011656 3 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Pyoderma D011711 5 associated lipids
Quadriplegia D011782 4 associated lipids
Radiodermatitis D011855 3 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Rhinitis D012220 10 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Parhi AK et al. Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. 2013 Bioorg. Med. Chem. Lett. pmid:23891185
Sánchez Valenzuela A et al. Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. 2013 Foodborne Pathog. Dis. pmid:23259502
Sanad YM et al. Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. 2013 Foodborne Pathog. Dis. pmid:23259503
Metzler K et al. Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. 2013 J. Antimicrob. Chemother. pmid:23169894
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400
Heelan K et al. Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. 2012 Sep-Oct Pediatr Dermatol pmid:21906149
Lian W et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. 2012 Oct-Dec Biosens Bioelectron pmid:22683249
Hapa A et al. Childhood pityriasis lichenoides and oral erythromycin. 2012 Nov-Dec Pediatr Dermatol pmid:22639857
Asai N et al. A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. 2012 Nov-Dec J Bras Pneumol pmid:23288130
Clementson B and Smidt AC Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. 2012 May-Jun Pediatr Dermatol pmid:22122785
Kuhn M et al. Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. 2012 Jul-Aug Berl. Munch. Tierarztl. Wochenschr. pmid:22919930
Jiang RS et al. Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. 2012 Jul-Aug Am J Rhinol Allergy pmid:22801017
Kuehne SA and Minton NP ClosTron-mediated engineering of Clostridium. 2012 Jul-Aug Bioengineered pmid:22750794
Miguel AI et al. Pediatric ocular rosacea: 2 cases. 2012 Jul-Aug Eur J Ophthalmol pmid:22267454
Amatya A et al. Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. 2012 Jan-Mar Kathmandu Univ Med J (KUMJ) pmid:22971864
Zhang H et al. Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. 2012 Jan-Feb Biotechnol. Prog. pmid:21905273
Pehr K Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. 2012 Jan-Feb J Cutan Med Surg pmid:22417996
Abdel Fattah NS and Darwish YW Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. 2012 Int. J. Dermatol. pmid:22928620
Kjeldgaard J et al. Residual antibiotics disrupt meat fermentation and increase risk of infection. 2012 MBio pmid:22930338
Sakatis MZ et al. Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. 2012 Chem. Res. Toxicol. pmid:22931300
Li SL et al. A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. 2012 Chin. Med. J. pmid:22931973
Waśko A et al. Genetic mechanisms of variation in erythromycin resistance in Lactobacillus rhamnosus strains. 2012 J. Antibiot. pmid:22948255
Moncrieffe MC et al. Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. 2012 J. Mol. Biol. pmid:22056329
Shimada M et al. Corneal ulcer associated with pepper spray exposure during military training. 2012 J Emerg Med pmid:22100497
Chouchani C et al. First report of mefA and msrA/msrB multidrug efflux pumps associated with blaTEM-1 β-lactamase in Enterococcus faecalis. 2012 Int. J. Infect. Dis. pmid:22137270
Zou X et al. Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter. 2012 Bioprocess Biosyst Eng pmid:22139481
McCusker KP and Fujimori DG The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. 2012 ACS Chem. Biol. pmid:22208312
Fischer H et al. In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. 2012 J. Med. Chem. pmid:22122484
Ducrotté P and Gourcerol G [Gastroparesis: pathophysiology and management]. 2012 Presse Med pmid:22154929
Krasniqi S et al. Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. 2012 Antimicrob. Agents Chemother. pmid:22083477
Back EE et al. High rates of perinatal group B Streptococcus clindamycin and erythromycin resistance in an upstate New York hospital. 2012 Antimicrob. Agents Chemother. pmid:22143529
Nimgaonkar A et al. Gastrointestinal dysmotility. 2012 Dig. Dis. Sci. pmid:22038542
Perić M et al. Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin. 2012 J. Med. Chem. pmid:22148880
Reil M et al. Seasonality of Clostridium difficile infections in Southern Germany. 2012 Epidemiol. Infect. pmid:22152928
Fazeli M et al. Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. 2012 J. Vet. Pharmacol. Ther. pmid:22066489
Kumar R et al. Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. 2012 Bioorg. Med. Chem. Lett. pmid:22153939
Reutenauer-Patte J et al. Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. 2012 Am. J. Pathol. pmid:22192627
Villaseñor-Sierra A et al. Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. 2012 Int. J. Infect. Dis. pmid:22217469
Luangtongkum T et al. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. 2012 Antimicrob. Agents Chemother. pmid:22183170
Soeters HM et al. Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. 2012 Antimicrob. Agents Chemother. pmid:22232291
Boswihi SS et al. Serotypes and antibiotic resistance in Group B streptococcus isolated from patients at the Maternity Hospital, Kuwait. 2012 J. Med. Microbiol. pmid:21903822
Jada S et al. Design and synthesis of novel magnolol derivatives as potential antimicrobial and antiproliferative compounds. 2012 Eur J Med Chem pmid:22424614
Osman KM et al. Antimicrobial susceptibility and molecular typing of multiple Chlamydiaceae species isolated from genital infection of women in Egypt. 2012 Microb. Drug Resist. pmid:22455539
Marlow N et al. Characteristics of children with cerebral palsy in the ORACLE children study. 2012 Dev Med Child Neurol pmid:22458348
Romøren M et al. Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. 2012 Br J Clin Pharmacol pmid:22463376
Lee CH et al. Case-crossover design: an alternative strategy for detecting drug-induced liver injury. 2012 J Clin Epidemiol pmid:22445086
Blode H et al. Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. 2012 Contraception pmid:22445438
Saxena S et al. Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus at a tertiary care hospital: implications for clinical therapy. 2012 J Commun Dis pmid:25151754
Kanazu T et al. Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. 2012 Biopharm Drug Dispos pmid:22447511
Liu X et al. Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment. 2012 Toxicol. Lett. pmid:22450446
Lialikov SA et al. [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. 2012 Antibiot. Khimioter. pmid:23700934
Rahube TO and Yost CK Characterization of a mobile and multiple resistance plasmid isolated from swine manure and its detection in soil after manure application. 2012 J. Appl. Microbiol. pmid:22486928
Bai J et al. Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. 2012 Mediators Inflamm. pmid:22701274
Vázquez-Sánchez D et al. Incidence and characterization of Staphylococcus aureus in fishery products marketed in Galicia (Northwest Spain). 2012 Int. J. Food Microbiol. pmid:22704064
Correa AM et al. [Pneumococcal bacteremia in adult patients at a hospital in Madrid: serotypes and susceptibility]. 2012 Rev Esp Quimioter pmid:22707105
Teodoro CR et al. Characterization of MLS(b) resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCCmec types. 2012 Microbiol. Immunol. pmid:22672011
Laurens C et al. Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France. 2012 Antimicrob. Agents Chemother. pmid:22644030
Thumu SC and Halami PM Presence of erythromycin and tetracycline resistance genes in lactic acid bacteria from fermented foods of Indian origin. 2012 Antonie Van Leeuwenhoek pmid:22644346
Sui Q et al. Identification of priority pharmaceuticals in the water environment of China. 2012 Chemosphere pmid:22591850
Constable PD et al. Evidence-based use of prokinetic drugs for abomasal disorders in cattle. 2012 Vet. Clin. North Am. Food Anim. Pract. pmid:22374117
Mehra T et al. Treatment of severe acne with low-dose isotretinoin. 2012 Acta Derm. Venereol. pmid:22377969
Ogawa W et al. Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. 2012 Gene pmid:22391093
Diacon AH et al. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. 2012 Antimicrob. Agents Chemother. pmid:22391540
Peano C et al. Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. 2012 Microb. Cell Fact. pmid:22401291
Chen CM Erythromycin for the treatment of feeding intolerance in preterm infants. 2012 Pediatr Neonatol pmid:22348487
Hossein nia R et al. An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. 2012 Bioorg. Med. Chem. Lett. pmid:22892120
Chuang CC et al. Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities. 2012 PLoS ONE pmid:22880135
Block SL Etiologic and therapeutic pitfalls of newborn conjunctivitis. 2012 Pediatr Ann pmid:22881420
Ishibashi K et al. Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery. 2012 Asian J Surg pmid:22720863
Chiba Y et al. Mechanism for folate-independent aldolase reaction catalyzed by serine hydroxymethyltransferase. 2012 FEBS J. pmid:22141341
Nelson CG and Burke TR Samarium iodide-mediated Reformatsky reactions for the stereoselective preparation of β-hydroxy-γ-amino acids: synthesis of isostatine and dolaisoleucine. 2012 J. Org. Chem. pmid:22136325
Zhou X et al. Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652. 2012 J. Nat. Prod. pmid:23215246
Sun J et al. Enterococcus faecalis from patients with chronic periodontitis: virulence and antimicrobial resistance traits and determinants. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:21660501
El-Adawy H et al. Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. 2012 Avian Dis. pmid:23397839
He JL et al. [Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]. 2012 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:23328096
Milberg P et al. Blockade of I(Ca) suppresses early afterdepolarizations and reduces transmural dispersion of repolarization in a whole heart model of chronic heart failure. 2012 Br. J. Pharmacol. pmid:22013922
Smith EM et al. In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. 2012 Aquat. Toxicol. pmid:22000335
Mercer BM et al. The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. 2012 Am. J. Obstet. Gynecol. pmid:22000668
Pendela M et al. Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. 2012 Anal Bioanal Chem pmid:22002558
Parhi A et al. Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. 2012 Bioorg. Med. Chem. Lett. pmid:23084900
Benet LZ A step closer to personalized chemotherapy: consideration of the influence of genetic variation in hepatic uptake transporters on the metabolism of CYP3A substrates. 2012 Clin. Pharmacol. Ther. pmid:23085879
Lu S and Zgurskaya HI Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter. 2012 Mol. Microbiol. pmid:23057817
Parhi A et al. Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. 2012 Bioorg. Med. Chem. Lett. pmid:23058886
Wilson BB et al. An atypical presentation of erythrasma. 2012 J. Am. Acad. Dermatol. pmid:23062922
Bech-Nielsen GV et al. Manipulation of the gut microbiota in C57BL/6 mice changes glucose tolerance without affecting weight development and gut mucosal immunity. 2012 Res. Vet. Sci. pmid:21543097
Zhou L et al. Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. 2012 BMC Microbiol. pmid:23043378
Cannon JA et al. Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. 2012 Dis. Colon Rectum pmid:23044677
Kaul M et al. A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. 2012 J. Med. Chem. pmid:23050700
Du Plessis LH et al. In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. 2012 J. Antibiot. pmid:23093037
Brenciani A et al. ICESp1116, the genetic element responsible for erm(B)-mediated, inducible resistance to erythromycin in Streptococcus pyogenes. 2012 Antimicrob. Agents Chemother. pmid:23027190
Koning S et al. Interventions for impetigo. 2012 Cochrane Database Syst Rev pmid:22258953
Zhou Q et al. SigB-dependent tolerance to protein synthesis-inhibiting antibiotics in Listeria monocytogenes EGDe. 2012 Curr. Microbiol. pmid:22143398
Lancaster CS et al. OATP1B1 polymorphism as a determinant of erythromycin disposition. 2012 Clin. Pharmacol. Ther. pmid:22990751
Rubio-López V et al. Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006). 2012 BMC Microbiol. pmid:22998619
Marks LR et al. The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. 2012 PLoS ONE pmid:22905269
Weisman LE et al. Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. 2012 Pediatr. Res. pmid:22907617