erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Parker DL et al. | Elevated International Normalized Ratio associated with concurrent use of ophthalmic erythromycin and warfarin. | 2010 | Am J Health Syst Pharm | pmid:20044367 |
Howard KB et al. | Azithromycin versus erythromycin for community-acquired pneumonia: a cost-minimization analysis. | 1999 | Am J Health Syst Pharm | pmid:10478989 |
Erythromycin resistance in Finland declines after reduction in macrolide use. | 1997 | Am J Health Syst Pharm | pmid:9359947 | |
Lestico MR and Smith AD | Stevens-Johnson syndrome following erythromycin administration. | 1995 | Am J Health Syst Pharm | pmid:8528839 |
Horn JR | Analysis of purported erythromycin-warfarin interaction. | 2010 | Am J Health Syst Pharm | pmid:20516463 |
Rosen RA | The use of antibiotics in the initial management of recent dog-bite wounds. | 1985 | Am J Emerg Med | pmid:3970747 |
Altieri M et al. | Antibiotic prophylaxis in intraoral wounds. | 1986 | Am J Emerg Med | pmid:3096345 |
Paris DG et al. | Torsades de pointes induced by erythromycin and terfenadine. | 1994 | Am J Emerg Med | pmid:7945604 |
Traub SJ et al. | Use of pharmaceutical promotility agents in the treatment of body packers. | 2003 | Am J Emerg Med | pmid:14574669 |
Ferguson DL et al. | Lichenoid lymphocytic vasculitis with a high component of histiocytes. Histogenetic implications in a specified clinical setting. | 1989 | Am J Dermatopathol | pmid:2729528 |
Tan HH | Antibacterial therapy for acne: a guide to selection and use of systemic agents. | 2003 | Am J Clin Dermatol | pmid:12688836 |
Taylor GA and Shalita AR | Benzoyl peroxide-based combination therapies for acne vulgaris: a comparative review. | 2004 | Am J Clin Dermatol | pmid:15301572 |
Asnes RS and Grebin B | Practical antibiotic therapy in children. | 1973 | Am Fam Physician | pmid:4546004 |
Snydman DR | Campylobacter Gastroenteritis. | 1982 | Am Fam Physician | pmid:7055019 |
Miller KE | Diagnosis and treatment of Chlamydia trachomatis infection. | 2006 | Am Fam Physician | pmid:16669564 |
McSherry JA | Mycoplasma pneumoniae infections. | 1983 | Am Fam Physician | pmid:6837403 |
Guckian JC | Complications of antimicrobial therapy. | 1973 | Am Fam Physician | pmid:4353071 |
Pagano JS and Sarubbi FA | Pneumonia. | 1972 | Am Fam Physician | pmid:4642154 |
Langer R and Binnick S | Treatment of acne vulgaris. | 1979 | Am Fam Physician | pmid:157066 |
Raz R and Bitnun S | Dilemmas of streptococcal pharyngitis. | 1987 | Am Fam Physician | pmid:3105301 |
Stott GA | New macrolide antibiotics: clarithromycin and azithromycin. | 1992 | Am Fam Physician | pmid:1325106 |
Constantine PA | Antibiotic therapy and serum digoxin toxicity. | 1998 | Am Fam Physician | pmid:9531908 |
Robinson M | Prokinetic therapy for gastroesophageal reflux disease. | 1995 | Am Fam Physician | pmid:7653432 |
Derrick CW and Dillon HC | Impetigo contagiosa. | 1971 | Am Fam Physician | pmid:5000340 |
Winkelman L | Recommended revision to endocarditis prophylaxis. | 1991 | Am Fam Physician | pmid:1950954 |
Kiselica D | Group A beta-hemolytic streptococcal pharyngitis: current clinical concepts. | 1994 | Am Fam Physician | pmid:8154403 |
Syphilis--recommended treatment schedules, 1976. | 1976 | Am Fam Physician | pmid:961559 | |
Luft FC | Antimicrobials in kidney and liver failure. | 1976 | Am Fam Physician | pmid:941822 |
Ackley AM | Legionnaires' disease: an update. | 1981 | Am Fam Physician | pmid:7020390 |
Johnson WT | Managing odontogenic infections. | 1984 | Am Fam Physician | pmid:6731235 |
Gonorrhea--recommended treatment schecules, 1974. | 1975 | Am Fam Physician | pmid:123699 | |
Culp ER | Ilosone update. | 1980 | Am Fam Physician | pmid:7377065 |
Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. | 2012 | Am Fam Physician | pmid:22335221 | |
Adamson L and Walum E | Insulin and IGF-1 mediated inhibition of apoptosis in CHO cells grown in suspension in a protein-free medium. | 2007 | Altern Lab Anim | pmid:17650954 |
San Pedro de Saenz B et al. | FDE to macrolides. | 2002 | Allergy | pmid:11991294 |
Florido Lopez JF et al. | Fixed eruption due to erythromycin. A case report. | 1991 | Allergy | pmid:1826819 |
López Serrano C et al. | Urticaria from erythromycin. | 1993 Nov-Dec | Allergol Immunopathol (Madr) | pmid:7512783 |
Sabbah A et al. | [Cell-mediated immunity in antibiotic therapy]. | 1988 | Allerg Immunol (Paris) | pmid:3401307 |
Sabbah A | [Teldane update. Interview with Dr. Alfred Sabbah, chief of the immuno-allergology laboratory of the C.H.U. d'Angers. Interview by Dr. Pierre Ceddaha]. | 1993 | Allerg Immunol (Paris) | pmid:8466639 |
Wessel F | [Peri-anesthesia allergies to antibiotics]. | 1998 | Allerg Immunol (Paris) | pmid:9684043 |
Mosonyi L et al. | [Infectious and neoplastic complications in rheumatoid arthritis]. | 1974-1975 | Allerg Immunol (Leipz) | pmid:4282826 |
Van Herwaarden MA et al. | The effect of motilin agonist ABT-229 on gastro-oesophageal reflux, oesophageal motility and lower oesophageal sphincter characteristics in GERD patients. | 2000 | Aliment. Pharmacol. Ther. | pmid:10759625 |
Ramirez B and Richter JE | Review article: promotility drugs in the treatment of gastro-oesophageal reflux disease. | 1993 | Aliment. Pharmacol. Ther. | pmid:8094981 |
Catnach SM et al. | Dose-dependent stimulation of gallbladder contraction by intravenous erythromycin in man. | 1993 | Aliment. Pharmacol. Ther. | pmid:8439638 |
Russo A et al. | Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis. | 2004 | Aliment. Pharmacol. Ther. | pmid:15274670 |
Verhagen MA et al. | Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. | 1997 | Aliment. Pharmacol. Ther. | pmid:9663833 |
Haans JJ and Masclee AA | Review article: The diagnosis and management of gastroparesis. | 2007 | Aliment. Pharmacol. Ther. | pmid:18081647 |
Bai Y et al. | Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. | 2011 | Aliment. Pharmacol. Ther. | pmid:21615438 |
Talley NJ et al. | Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121915 |
Emmanuel AV et al. | Erythromycin for the treatment of chronic intestinal pseudo-obstruction: description of six cases with a positive response. | 2004 | Aliment. Pharmacol. Ther. | pmid:15023171 |
Netzer P et al. | Effects of ABT-229, a motilin agonist, on acid reflux, oesophageal motility and gastric emptying in patients with gastro-oesophageal reflux disease. | 2002 | Aliment. Pharmacol. Ther. | pmid:12182748 |
Athanasakis E et al. | Octreotide enhances the accelerating effect of erythromycin on gastric emptying in healthy subjects. | 2002 | Aliment. Pharmacol. Ther. | pmid:12182757 |
McCallum RW and Cynshi O | Clinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study. | 2007 | Aliment. Pharmacol. Ther. | pmid:17894654 |
Chen CL et al. | Efficacy of a motilin receptor agonist (ABT-229) for the treatment of gastro-oesophageal reflux disease. | 2002 | Aliment. Pharmacol. Ther. | pmid:11929393 |
Winstead NS and Wilcox CM | Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage: a cost-effectiveness analysis. | 2007 | Aliment. Pharmacol. Ther. | pmid:17848180 |
Bell GD et al. | Short report: omeprazole plus antibiotic combinations for the eradication of metronidazole-resistant Helicobacter pylori. | 1992 | Aliment. Pharmacol. Ther. | pmid:1486161 |
Brand RM et al. | Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218087 |
Annese V et al. | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218089 |
van Erpecum KJ et al. | Review article: agents affecting gall-bladder motility--role in treatment and prevention of gallstones. | 2000 | Aliment. Pharmacol. Ther. | pmid:10903008 |
Chiba T et al. | Motilides accelerate regional gastrointestinal transit in the dog. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886053 |
Minocha A et al. | Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. | 1995 | Aliment. Pharmacol. Ther. | pmid:8580273 |
Landry C et al. | Could oral erythromycin optimize high energy continuous enteral nutrition? | 1996 | Aliment. Pharmacol. Ther. | pmid:8971296 |
Ehrenpreis ED et al. | Which form of erythromycin should be used to treat gastroparesis? A pharmacokinetic analysis. | 1998 | Aliment. Pharmacol. Ther. | pmid:9690728 |
Jameson JS et al. | Oral or intravenous erythromycin has no effect on human distal colonic motility. | 1992 | Aliment. Pharmacol. Ther. | pmid:1420750 |
Osato MS et al. | Comparative efficacy of new investigational agents against Helicobacter pylori. | 2001 | Aliment. Pharmacol. Ther. | pmid:11284777 |
Medhus AW et al. | Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel. | 2000 | Aliment. Pharmacol. Ther. | pmid:10651665 |
Curry JI et al. | Review article: erythromycin as a prokinetic agent in infants and children. | 2001 | Aliment. Pharmacol. Ther. | pmid:11328252 |
Kendall BJ et al. | The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146779 |
Boecxstaens V et al. | Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. | 2011 | Aliment. Pharmacol. Ther. | pmid:21517922 |
Laine L et al. | Prospective evaluation of the macrolide antibiotic dirithromycin for the treatment of Helicobacter pylori. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791949 |
Wehrmann T et al. | Effect of erythromycin on human biliary motility. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791972 |
BOURICHON J | [Importance of the suppository form in the administration of propionyl-erythromycin to children]. | 1962 | Alger Medicale | pmid:13871918 |
LEBON J et al. | [Staphylococcal diarrhea after terramycin administration; cure by erythromycin]. | 1955 | Alger Medicale | pmid:14398597 |
Thornton JB and Harris JH | The prevention of bacterial endocarditis. A new approach to a changing disease. | 1986 | Ala J Med Sci | pmid:3953983 |
Simakova MG et al. | [Clinical aspects, diagnosis and treatment of intrauterine infections]. | 1995 | Akush Ginekol (Mosk) | pmid:7485765 |
Mezinova NN et al. | [Effect of anti-chlamydial drugs on the effectiveness of the treatment of habitual abortion]. | 1991 | Akush Ginekol (Mosk) | pmid:1951968 |
Mezinova NN and Chuchupalov PD | [Endometrial Chlamydia infection in women with habitual abortion]. | 1992 | Akush Ginekol (Mosk) | pmid:1476220 |
Kotua EN and Moroz AF | [Erythromycin-ascorbinate therapy of pregnant rats with staphylococcal infections caused by staphylococcal strains both sensitive and resistant to erythromycin]. | 1971 | Akush Ginekol (Mosk) | pmid:5138198 |
Kotua EN and Moroz AF | [Passage of erythromycin and ristomycin into blood, placenta, fetus and amniotic fluid during various stages of pregnancy in generalized staphylococcal infection in albino rats]. | 1971 | Akush Ginekol (Mosk) | pmid:4328638 |
Moss AA et al. | Radiologic and clinical assessment of broad-spectrum antibiotic therapy in Crohn's disease. | 1978 | AJR Am J Roentgenol | pmid:101028 |
Stickney RH et al. | Chlamydia trachomatis: a cause of an infantile pneumonia syndrome. | 1978 | AJR Am J Roentgenol | pmid:101061 |
Lauenstein TC et al. | Time-resolved three-dimensional MR imaging of gastric emptying modified by IV administration of erythromycin. | 2003 | AJR Am J Roentgenol | pmid:12704042 |
Wagner CM | The care and management of pertussis in pediatric patients. | 2001 Mar-Apr | Air Med. J. | pmid:11250611 |
Warning against using erythromycin (even orally) while using protease inhibitors or certain other drugs. | 2004 | AIDS Treat News | pmid:15595151 | |
Schlecht HP et al. | Images in HIV/AIDS. HIV-associated lymphogranuloma venereum proctitis. | 2007 | AIDS Read | pmid:17396331 |
Berger TG and Koehler JE | Bacillary angiomatosis. | 1993-1994 | AIDS Clin Rev | pmid:8217903 |
van der Wouw PA et al. | Disseminated cat-scratch disease in a patient with AIDS. | 1989 | AIDS | pmid:2515881 |
Taha TE et al. | A phase III clinical trial of antibiotics to reduce chorioamnionitis-related perinatal HIV-1 transmission. | 2006 | AIDS | pmid:16816561 |
Takei M et al. | [Studies on the mixed culture of Candida and Lactobacillus. 3. Influences of the antibiotics (EM and TM)]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5236280 |
Sugiyama H | [Experimental studies on control of dental caries. 1. Preventive effect of Erythromycin]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5244796 |
Sugiyama H | [Experimental studies on control of dental caries. 2. Erythromycin and oral microbial flora]. | 1968 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5261349 |
Chen SZ et al. | [Correlation of HERG K+ channel protein expression to chemosensitivity of tumor cells to doxorubicin and its modulation by erythromycin]. | 2005 | Ai Zheng | pmid:16086867 |
Hashiba H et al. | Transformation of Lactobacillus helveticus subsp. jugurti with plasmid pLHR by electroporation. | 1990 | Agric. Biol. Chem. | pmid:1368569 |
LIGNY G and VIGUIE R | [DESTRUCTION OF THE INTESTINAL FLORA BY ANTIBIOTIC THERAPY]. | 1964 May-Jun | Agressologie | pmid:14185522 |
Friedman GD and Selby JV | Epidemiological screening for potentially carcinogenic drugs. | 1990 | Agents Actions Suppl. | pmid:2316434 |
Carević O and Djokić S | Comparative studies on the effects of erythromycin A and azithromycin upon extracellular release of lysosomal enzymes in inflammatory processes. | 1988 | Agents Actions | pmid:2847507 |
Campbell G et al. | A cautionary tale: delayed onset rhabdomyolysis due to erythromycin/simvastatin interaction. | 2007 | Age Ageing | pmid:17913761 |
Haboubi NY et al. | Duodenal mucosal morphometry of elderly patients with small intestinal bacterial overgrowth: response to antibiotic treatment. | 1991 | Age Ageing | pmid:2028847 |
Roddis MJ | Antibiotic-associated colitis: a retrospective study of fifteen cases. | 1978 | Age Ageing | pmid:101026 |
Olatunji FO et al. | Non-gonococcal bacterial agents of conjunctivitis and their antibiotic susceptibility patterns in Ilorin, Nigeria. | 2007 | Afr J Med Med Sci | pmid:18390064 |