erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Gastroparesis D018589 2 associated lipids
Dyspepsia D004415 5 associated lipids
Asthenia D001247 5 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Tooth Diseases D014076 2 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Tourette Syndrome D005879 3 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Bronchiectasis D001987 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Parotitis D010309 4 associated lipids
Dysarthria D004401 2 associated lipids
Lyme Disease D008193 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bile Reflux D001655 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Animal Diseases D000820 2 associated lipids
Legionellosis D007876 3 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Blepharitis D001762 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Toothache D014098 3 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Pleuropneumonia D011001 3 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Intestinal Atresia D007409 3 associated lipids
Foot Ulcer D016523 4 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Balanitis D001446 4 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Pelchovich G et al. The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. 2013 Int. J. Med. Microbiol. pmid:23972615
Hirano E et al. Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. 2013 Int. J. Cardiol. pmid:22727964
Zhang Y et al. Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23481648
Sundermann U et al. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. 2013 ACS Chem. Biol. pmid:23181268
Everson GT et al. Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy. 2013 Liver Transpl. pmid:23239552
Kelmer G et al. Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses. 2013 J. Vet. Pharmacol. Ther. pmid:23240633
Li N et al. Effect of corilagin on membrane permeability of Escherichia coli, Staphylococcus aureus and Candida albicans. 2013 Phytother Res pmid:23192753
Liang JH et al. Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. 2013 Bioorg. Med. Chem. Lett. pmid:23375796
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247
Heelan K et al. Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. 2012 Sep-Oct Pediatr Dermatol pmid:21906149
Lian W et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. 2012 Oct-Dec Biosens Bioelectron pmid:22683249
Hapa A et al. Childhood pityriasis lichenoides and oral erythromycin. 2012 Nov-Dec Pediatr Dermatol pmid:22639857
Asai N et al. A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. 2012 Nov-Dec J Bras Pneumol pmid:23288130
Clementson B and Smidt AC Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. 2012 May-Jun Pediatr Dermatol pmid:22122785
Kuhn M et al. Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. 2012 Jul-Aug Berl. Munch. Tierarztl. Wochenschr. pmid:22919930
Jiang RS et al. Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. 2012 Jul-Aug Am J Rhinol Allergy pmid:22801017
Kuehne SA and Minton NP ClosTron-mediated engineering of Clostridium. 2012 Jul-Aug Bioengineered pmid:22750794
Miguel AI et al. Pediatric ocular rosacea: 2 cases. 2012 Jul-Aug Eur J Ophthalmol pmid:22267454
Amatya A et al. Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. 2012 Jan-Mar Kathmandu Univ Med J (KUMJ) pmid:22971864
Zhang H et al. Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. 2012 Jan-Feb Biotechnol. Prog. pmid:21905273
Pehr K Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. 2012 Jan-Feb J Cutan Med Surg pmid:22417996
Padovan J et al. Investigating the barriers to bioavailability of macrolide antibiotics in the rat. 2012 Eur J Drug Metab Pharmacokinet pmid:22113743
Wills RH et al. Structural characterization of polyketides using high mass accuracy tandem mass spectrometry. 2012 Anal. Chem. pmid:22985101
Sugimoto T et al. Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. 2012 Bioorg. Med. Chem. pmid:22925450
Sugimoto T et al. Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. 2012 Bioorg. Med. Chem. Lett. pmid:22858102
Zou MX et al. Antimicrobial resistance and molecular epidemiological characteristics of clinical isolates of Staphylococcus aureus in Changsha area. 2012 Chin. Med. J. pmid:22882850
März A et al. Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. 2012 Anal Bioanal Chem pmid:21822777
Zaknoon F et al. Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. 2012 Antimicrob. Agents Chemother. pmid:22751534
Gant CM et al. Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. 2012 Antimicrob. Agents Chemother. pmid:22751535
Kim J et al. Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. 2012 J. Microbiol. pmid:22752920
Arakawa K et al. The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. 2012 Chembiochem pmid:22761035
García-Pérez ME et al. Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. 2012 Food Chem pmid:22953840
De Sousa A and Kalra G Drug therapy of attention deficit hyperactivity disorder: current trends. 2012 Mens Sana Monogr pmid:22654382
Ullrich K et al. Neuroretinitis following bull ant sting. 2012 BMJ Case Rep pmid:22865803
Pollett S et al. Campylobacter antimicrobial resistance in Peru: a ten-year observational study. 2012 BMC Infect. Dis. pmid:22898609
Licona-Cassani C et al. Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. 2012 Antonie Van Leeuwenhoek pmid:22847261
Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. 2012 Prescrire Int pmid:22852287
Yuzawa S et al. Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. 2012 Biochemistry pmid:22509729
Shimizu S et al. Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. 2012 J. Agric. Food Chem. pmid:22694300
Perry DM et al. Identification and characterization of protein phosphatase 2C activation by ceramide. 2012 J. Lipid Res. pmid:22615346
Geddes BA and Oresnik IJ Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. 2012 Microbiology (Reading, Engl.) pmid:22609752
Pinto TF et al. Tolerance to enteral nutrition therapy in traumatic brain injury patients. 2012 Brain Inj pmid:22571511
Deane AM et al. Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. 2012 Am. J. Clin. Nutr. pmid:22572649
Senhorinho GN et al. Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. 2012 Anaerobe pmid:22609780
Bidet P et al. Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:22610663
Rocco L et al. Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. 2012 Environ. Toxicol. pmid:21384490
Liu X et al. [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. 2012 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:23156807
Li M et al. Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro. 2012 Int. Immunopharmacol. pmid:22265969
El Hafidi N et al. [Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis]. 2012 Rev. Neurol. (Paris) pmid:22244792
Tolosa L et al. Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. 2012 Toxicol. Sci. pmid:22331495