erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

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Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rhinitis D012220 10 associated lipids
Skin Ulcer D012883 6 associated lipids
Heart Diseases D006331 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Multiple Myeloma D009101 13 associated lipids
Quadriplegia D011782 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Porphyrias D011164 2 associated lipids
Femoral Fractures D005264 7 associated lipids
Hematuria D006417 13 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
HEDENIUS P and TUNEVALL HG [Erythromycin, its antibacterial effect in vitro, its absorption and excretion, with a preliminary report on a series of cases with erythromycin therapy]. 1953 Sven Lakartidn pmid:13113605
Wapnick S et al. Reduction of postoperative infection in elective colon surgery with preoperative administration of kanamycin and erythromycin. 1979 Surgery pmid:371048
Pennathur A et al. Erythromycin, motilin, and the esophagus. 1993 Surgery pmid:8342132
Bell GA et al. Prophylactic antibiotics in elective colon surgery. 1983 Surgery pmid:6849206
Hocking MP Postoperative gastroparesis and tachygastria--response to electric stimulation and erythromycin. 1993 Surgery pmid:8367808
Kaufman HS et al. The effect of erythromycin on motility of the duodenum, sphincter of Oddi, and gallbladder in the prairie dog. 1993 Surgery pmid:8367809
Cohen SR et al. Healing of ischemic colonic anastomoses in the rat: role of antibiotic preparation. 1985 Surgery pmid:3983820
Parry SW et al. Acalculous hypersensitivity cholecystitis: hypothesis of a new clinicopathologic entity. 1988 Surgery pmid:3187904
Hinchey EJ et al. Metronidazole as a prophylactic agent in wound infection after colon surgery. 1983 Surgery pmid:6336863
Nishikawa K et al. Functional characteristics of the pylorus in patients undergoing pylorus--preserving gastrectomy for early gastric cancer. 2002 Surgery pmid:12075173
Varnell J and Pemberton LB Risk factors in colostomy closure. 1981 Surgery pmid:7245028
Jarrett F et al. Clinical experience with prophylactic antibiotic bowel suppression in burn patients. 1978 Surgery pmid:347612
Washington BC et al. Cefamandole-erythromycin-heparin peritoneal irrigation: an adjunct to the surgical treatment of diffuse bacterial peritonitis. 1983 Surgery pmid:6623358
Barnes RW et al. Studies of sterility of calf venous blood. 1968 Surgery pmid:4300855
Nakabayashi T et al. Erythromycin induces pyloric relaxation accompanied by a contraction of the gastric body after pylorus-preserving gastrectomy. 2003 Surgery pmid:12796733
Sigaroudinia MO and Quayle AR Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. 2011 Surgeon pmid:21550524
Ishibashi K et al. Short-term intravenous antimicrobial prophylaxis for elective rectal cancer surgery: results of a prospective randomized non-inferiority trial. 2014 Surg. Today pmid:23989910
LaMont JT Postoperative juandice. 1974 Surg. Clin. North Am. pmid:4597042
Condon RE and Nichols RL The present position of the neomycin-erythromycin bowal prep. 1975 Surg. Clin. North Am. pmid:1105832
Farmer RG Preoperative preparation of the patients with carcinoma of the colon. 1975 Surg. Clin. North Am. pmid:1105833
Jones FE et al. Experimental evaluation of "instant" preparation of the colon with povidone-iodine. 1975 Surg. Clin. North Am. pmid:1198291
Richards KE et al. Monilial sepsis in the surgical patient. 1972 Surg. Clin. North Am. pmid:4344114
Carver DH Antibiotics in pediatric surgery. 1970 Surg. Clin. North Am. pmid:4317769
Nichols RL and Condon RE Antibiotic preparation of the colon: failure of commonly used regimens. 1971 Surg. Clin. North Am. pmid:4932924
Yiannakopoulou E et al. Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review. 2012 Surg Laparosc Endosc Percutan Tech pmid:22678313
Nichols RL et al. Effect of preoperative neomycin-erythromycin intestinal preparation on the incidence of infectious complications following colon surgery. 1973. 2000 Surg Infect (Larchmt) pmid:12594901
Parker TH and O'Leary JP Effect of preparation of the small intestine on microflora and postoperative wound infection. 1978 Surg Gynecol Obstet pmid:625675
Vargish T et al. A randomized prospective evaluation of orally administered antibiotics in operations on the colon. 1978 Surg Gynecol Obstet pmid:341376
Figueras-Felip J et al. Oral is superior to systemic antibiotic prophylaxis in operations upon the colon and rectum. 1984 Surg Gynecol Obstet pmid:6710299
Salvati EP et al. Value of subcutaneous and intraperitoneal antibiotics in reducing infection in clean contaminated operations of the colon. 1988 Surg Gynecol Obstet pmid:3420506
Mehigan D et al. The role of systemic antibiotics in operations upon the colon. 1981 Surg Gynecol Obstet pmid:7280947
PULASKI EJ and WESOLOWSKI SA The use of erythromycin in certain surgical infections. 1954 Surg Gynecol Obstet pmid:13137583
Eaton RG and Butsch DP Antibiotic guidelines for hand infections. 1970 Surg Gynecol Obstet pmid:4312012
Bell GA et al. Intravenous prophylactic antimicrobial drugs in elective colorectal operations. 1983 Surg Gynecol Obstet pmid:6828981
Roberts TL et al. Antibiotic penetration into normal and inflamed tissues as reflected by peripheral lymph. 1977 Surg Forum pmid:617531
GERBER B et al. The excretion of antibiotics in pancreatic fluid. 1957 Surg Forum pmid:13529603
Jarrett F et al. Antibiotic bowel preparation and burn wound colonization. 1976 Surg Forum pmid:1019996
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989
Hau T et al. Antibiotics in surgery. 1983 Surg Annu pmid:6353632
Lanzarotti C and Rossi G Effect of netupitant, a highly selective NK₁ receptor antagonist, on the pharmacokinetics of midazolam, erythromycin, and dexamethasone. 2013 Support Care Cancer pmid:23729226
Nelson K et al. Cancer and chemotherapy-related upper gastrointestinal symptoms: the role of abnormal gastric motor function and its evaluation in cancer patients. 2002 Support Care Cancer pmid:12353123
WASZ-HOECKERT O [CHEMOTHERAPEUTIC AGENTS AND ANTIBIOTICS IN PEDIATRICS]. 1964 Suom Laakaril pmid:14145132
KAIPAINEN WJ [Erythromycin]. 1954 Suom Laakaril pmid:13178935
Jokinen MA Bacteremia following dental extraction and its prophylaxis. 1970 Suom Hammaslaak Toim pmid:4989524
Unge J et al. The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance. 1998 Structure pmid:9862810
Schlünzen F et al. Structural basis for the antibiotic activity of ketolides and azalides. 2003 Structure pmid:12623020
Wekselman I et al. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. 2017 Structure pmid:28689968
Pecevski J et al. The effect of erythromycin and its thiocarbamide derivative on the induction of meiotic chromosome rearrangements in irradiated male mice. 1977 Strahlentherapie pmid:841613
Tsarev VN et al. [A trial of the use of rulid, sumamed and makropen in the combined treatment of generalized periodontitis at a stage of exacerbation]. 1997 Stomatologiia (Mosk) pmid:9411932
Filatova NA et al. [The prospects for using the new macrolide antibiotic azithromycin (Sumamed) in the combined treatment of periodontitis]. 1995 Stomatologiia (Mosk) pmid:7770869