erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rhinitis D012220 10 associated lipids
Skin Ulcer D012883 6 associated lipids
Heart Diseases D006331 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Multiple Myeloma D009101 13 associated lipids
Quadriplegia D011782 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Porphyrias D011164 2 associated lipids
Femoral Fractures D005264 7 associated lipids
Hematuria D006417 13 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Padovan J et al. Investigating the barriers to bioavailability of macrolide antibiotics in the rat. 2012 Eur J Drug Metab Pharmacokinet pmid:22113743
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Sugimoto T et al. Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. 2012 Bioorg. Med. Chem. Lett. pmid:22858102
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Pollett S et al. Campylobacter antimicrobial resistance in Peru: a ten-year observational study. 2012 BMC Infect. Dis. pmid:22898609
Licona-Cassani C et al. Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. 2012 Antonie Van Leeuwenhoek pmid:22847261
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Deane AM et al. Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. 2012 Am. J. Clin. Nutr. pmid:22572649
Senhorinho GN et al. Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. 2012 Anaerobe pmid:22609780
Bidet P et al. Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:22610663
Rocco L et al. Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. 2012 Environ. Toxicol. pmid:21384490
Liu X et al. [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. 2012 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:23156807
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Tolosa L et al. Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. 2012 Toxicol. Sci. pmid:22331495
Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
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Otsu K et al. Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. 2011 Pharmacology pmid:22116077
Song W et al. Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. 2011 Int J Nanomedicine pmid:22228990
Spigaglia P et al. Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. 2011 Emerging Infect. Dis. pmid:21291621
Huppertz A et al. Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). 2011 J Magn Reson Imaging pmid:21274983
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Ahmetagic A et al. Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. 2011 Plasmid pmid:21839110
Zhou L et al. Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. 2011 Vaccine pmid:21839135
Wu J et al. Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. 2011 Appl. Environ. Microbiol. pmid:21841022
Senthilkumaran S and Subramanian PT Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. 2011 Indian Pediatr pmid:22711153
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Andini N and Nash KA Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. 2011 FEMS Microbiol. Lett. pmid:21718348
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Boghigian BA et al. Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. 2011 J. Ind. Microbiol. Biotechnol. pmid:21487833
Miyashita N et al. Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. 2011 J. Infect. Chemother. pmid:20676912
Richter SS et al. Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. 2011 Antimicrob. Agents Chemother. pmid:21709080
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Guo L et al. Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. 2011 Toxicol. Sci. pmid:21693436
Modali SD and Zgurskaya HI The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. 2011 Mol. Microbiol. pmid:21696464
Manneck T et al. Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. 2011 Exp. Parasitol. pmid:20732321
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Fan C and He J Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. 2011 Water Res. pmid:21482429
Franke RM et al. Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. 2011 Clin. Pharmacol. Ther. pmid:21451505
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Li Y et al. Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. 2011 J. Appl. Microbiol. pmid:20961364
Vuppalanchi R et al. Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. 2011 J. Clin. Gastroenterol. pmid:20962670