erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
Naot Y et al. | IgM and IgG antibody response in two immunosuppressed patients with Legionnaires' disease. Evidence of reactivation of latent infection. | 1982 | Am. J. Med. | pmid:6756135 |
Lipsky BA et al. | Ofloxacin treatment of Chlamydia pneumoniae (strain TWAR) lower respiratory tract infections. | 1990 | Am. J. Med. | pmid:2252040 |
Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
Kugler JW et al. | Nosocomial Legionnaires' disease. Occurrence in recipients of bone marrow transplants. | 1983 | Am. J. Med. | pmid:6337488 |
Moellering RC et al. | Endocarditis due to group D streptococci. Comparison of disease caused by streptococcus bovis with that produced by the enterococci. | 1974 | Am. J. Med. | pmid:4843895 |
Bent S et al. | Antibiotics in acute bronchitis: a meta-analysis. | 1999 | Am. J. Med. | pmid:10403354 |
Stamm WE | Azithromycin in the treatment of uncomplicated genital chlamydial infections. | 1991 | Am. J. Med. | pmid:1656737 |
Hooton TM | A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. | 1991 | Am. J. Med. | pmid:1656738 |
Casiano RR | Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. | 1991 | Am. J. Med. | pmid:1656739 |
Dark D | Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. | 1991 | Am. J. Med. | pmid:1656740 |
Mallory SB | Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. | 1991 | Am. J. Med. | pmid:1656741 |
Hopkins S | Clinical toleration and safety of azithromycin. | 1991 | Am. J. Med. | pmid:1656742 |
Friedland L et al. | Ocular and pericardial involvement in Legionnaires' disease. | 1984 | Am. J. Med. | pmid:6507461 |
Schentag JJ and Ballow CH | Tissue-directed pharmacokinetics. | 1991 | Am. J. Med. | pmid:1656743 |
Wing EJ et al. | Successful treatment of Legionella micdadei (Pittsburgh pneumonia agent) pneumonia with erythromycin. | 1981 | Am. J. Med. | pmid:7304656 |
Nastro LJ and Finegold SM | Endocarditis due to anaerobic gram-negative bacilli. | 1973 | Am. J. Med. | pmid:4696007 |
Quintiliani R and Hymans PJ | The association of bacteremic Haemophilus influenzae pneumonia in adults with typable strains. | 1971 | Am. J. Med. | pmid:5314534 |
Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
SOLOMON S and JOHNSTON B | The clinical use of erythromycin. | 1955 | Am. J. Med. Sci. | pmid:13268445 |
Kislak JW et al. | Susceptibility of pneumococci to nine antibiotics. | 1965 | Am. J. Med. Sci. | pmid:4378532 |
Kayser FH and Mak TM | Methicillin-resistant staphylococci. | 1972 | Am. J. Med. Sci. | pmid:4486503 |
AUSTRIAN R and ROSENBLUM R | The relative efficacy of erythromycin (ilotycin) and of penicillin in the treatment of pneumococcal lobar pneumonia. | 1953 | Am. J. Med. Sci. | pmid:13104398 |
Simon HJ | Antimicrobial susceptibility of group D hemolytic streptococci (enterococci). | 1967 | Am. J. Med. Sci. | pmid:5180810 |
BLOUGH HA et al. | Serum levels and clinical results with erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:13801645 |
CICCANTELLI MJ and GARRY MW | Erythromycin: an evaluation for clinical toxicity. | 1956 | Am. J. Med. Sci. | pmid:13362260 |
ROBINSON MM | Hepatic dysfunction associated with triacetyloleandomycin and propionyl erythromycin ester lauryl sulfate. | 1962 | Am. J. Med. Sci. | pmid:14492926 |
Devasia RA et al. | Compliance with azithromycin versus erythromycin in the setting of a pertussis outbreak. | 2009 | Am. J. Med. Sci. | pmid:19301451 |
Williams ME et al. | Legionnaires' disease with acute renal failure. | 1980 May-Jun | Am. J. Med. Sci. | pmid:7424965 |
Toala P et al. | Susceptibility of group D streptococcus (enterococcus) to 21 antibiotics in vitro, with special reference to species differences. | 1969 | Am. J. Med. Sci. | pmid:4984452 |
HIRSCH HA and FINLAND M | Effect of food on the absorption of erythromycin propionate, erythromycin stearate and triacetyloleandomycin. | 1959 | Am. J. Med. Sci. | pmid:13661157 |
Holoshitz J et al. | Listeria monocytogenes pericarditis in a chronically hemodialyzed patient. | 1984 Jul-Aug | Am. J. Med. Sci. | pmid:6465192 |
Feigin RD et al. | Treatment of penicillin-resistant staphylococcal infections with clindamycin. | 1971 | Am. J. Med. Sci. | pmid:5578775 |
GRIFFITH RS and BLACK HR | COMPARISON OF THE BLOOD LEVELS OBTAINED AFTER SINGLE AND MULTIPLE DOSES OF ERYTHROMYCIN ESTOLATE AND ERYTHROMYCIN STEARATE. | 1964 | Am. J. Med. Sci. | pmid:14106882 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |
HIRSCH HA et al. | Effect of food on absorption of a new form of erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:14401969 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
Oppenheimer S and Turek M | Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. | 1968 | Am. J. Med. Sci. | pmid:4386951 |
CLAPPER WE et al. | THE SUSCEPTIBILITY OF CERTAIN BACTERIA TO LINCOMYCIN AS RELATED TO ATTAINABLE SERUM LEVELS IN HUMAN ADULTS. | 1964 | Am. J. Med. Sci. | pmid:14130319 |
FISCHER HW and HOAK JC | MIMICRY OF ACUTE CHOLECYSTITIS BY ERYTHROMYCIN ESTOLATE REACTIONS. REPORT OF 2 CASES. | 1964 | Am. J. Med. Sci. | pmid:14130320 |
McCabe WR and Lorian V | Comparison of the antibacterial activity of rifampicin and other antibiotics. | 1968 | Am. J. Med. Sci. | pmid:4387027 |
Martinez JA et al. | Diffuse panbronchiolitis in Latin America. | 2000 | Am. J. Med. Sci. | pmid:10746829 |
Baird IM et al. | Case report. Clinical manifestations and treatment of Legionnaires' disease. | 1979 Mar-Apr | Am. J. Med. Sci. | pmid:463949 |
Gray BM | Case report: Rhodococcus equi pneumonia in a patient infected by the human immunodeficiency virus. | 1992 | Am. J. Med. Sci. | pmid:1595781 |
Rao KV and Ralston RA | Meningitis due to Campylobacter fetus intestinalis in a kidney transplant recipient. A case report. | 1987 | Am. J. Nephrol. | pmid:3324765 |
Andrews JI et al. | Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere. | 2000 | Am. J. Obstet. Gynecol. | pmid:11035326 |
Mercer BM et al. | Prenatal screening for group B Streptococcus. I. Impact of antepartum screening on antenatal prophylaxis and intrapartum care. | 1995 | Am. J. Obstet. Gynecol. | pmid:7573254 |
Campbell WF and Dodson MG | Clindamycin therapy for Chlamydia trachomatis in women. | 1990 | Am. J. Obstet. Gynecol. | pmid:2178426 |
Croak A et al. | Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio. | 2003 | Am. J. Obstet. Gynecol. | pmid:12748459 |
Milwidsky A et al. | Direct inhibition of proteases and cervical plasminogen activator by antibiotics. | 1992 | Am. J. Obstet. Gynecol. | pmid:1536241 |