erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hearing Loss, Sensorineural D006319 8 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Bacteremia D016470 9 associated lipids
Urethritis D014526 9 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Sinusitis D012852 9 associated lipids
Cross Infection D003428 9 associated lipids
Cleft Palate D002972 9 associated lipids
Osteitis D010000 10 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Rhinitis D012220 10 associated lipids
Long QT Syndrome D008133 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hearing Disorders D006311 10 associated lipids
Pancreatitis D010195 10 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Dyspnea D004417 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Pneumonia D011014 10 associated lipids
Sepsis D018805 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Otitis Media D010033 12 associated lipids
Wound Infection D014946 12 associated lipids
Crohn Disease D003424 12 associated lipids
Eye Diseases D005128 12 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Death, Sudden D003645 12 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Endophthalmitis D009877 12 associated lipids
Listeriosis D008088 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Urticaria D014581 13 associated lipids
Critical Illness D016638 13 associated lipids
Hematuria D006417 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Abscess D000038 13 associated lipids
Rosacea D012393 13 associated lipids
Multiple Myeloma D009101 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
TartakovskiÄ­ IS et al. [The action of interferon preparations on strains of Legionella of various serogroups and species]. 1988 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:2469268
Chimirov OB [Sensitivity to the differential dose of erythromycin and oleandomycin of various holarctic strains of tularemia microbe isolated in the Kazakh SSR]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:150182
Ivashchenko VD [Use of embryonic intestinal tissue culture, infected with dysentery bicilli, for study of the efficacy of chemotherapeutic preparations]. 1973 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:4594209
Zueva VS and Linevich IuG [Mechanism of disorders of transmission of extrachromosomal determinants of resistance in staphylococci]. 1971 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:5135463
Zueva VS and Pavlov EP [The prevalence of staphylococci with extrachromosomal drug resistance factors in different collectives]. 1972 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:4563840
Wu DQ et al. [The expression of transforming growth factor beta-1 in rat model of chronic obstructive pulmonary disease and the effects of early drugs intervention]. 2004 Zhejiang Da Xue Xue Bao Yi Xue Ban pmid:15476327
Xu G [Regulating effect of electro-acupuncture on dysrythmia of gastro-colonic electric activity induced by erythromycine in rabbits]. 1994 Zhen Ci Yan Jiu pmid:7834859
Wang LQ et al. [Pharmacokinetics of erythromycin stinoprate capsule]. 2005 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:15898434
Lin XM et al. [Influence of neferine and erythromycin on cellular GSH concentration in K562/A02 cell line]. 2004 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:16136961
Xie L et al. [Efficacy of low-dose oral erythromycin as an adjuvant therapy for cytomegalovirus infection]. 2010 Zhongguo Dang Dai Er Ke Za Zhi pmid:20199738
Yang Y [Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. 2008 Zhongguo Dang Dai Er Ke Za Zhi pmid:18289489
Thomas W and Speer CP Prevention and therapy of bronchopulmonary dysplasia - evidence and clinical practice. 2007 Zhongguo Dang Dai Er Ke Za Zhi pmid:17582275
Yu M et al. [Mechanism reversing MDR of K562/A02 by garlicin combined with erythromycin]. 2008 Zhongguo Shi Yan Xue Ye Xue Za Zhi pmid:18928592
Du Y and He Q [The mechanism of alleviation of paraquat induced vascular endothelial permeability by erythromycin through adenosine 3'5'-cyclic monophosphate pathway]. 2009 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:19930884
Lu NF et al. [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]. 2010 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:20092709
Wang H et al. Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:10452125
Huang SK et al. [A combined perfusion-compartmental pharmacokinetic model used to estimate presystemic metabolism of erythromycin in dogs]. 1986 Zhongguo Yao Li Xue Bao pmid:2954396
Ye H et al. Antimycoplasmal activities of (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10 -[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine -6-carboxylic acid (YH-6) in comparison with other antibiotics in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:11270970
Lei PS et al. [Advance in synthesis of ketolides, a new class of erythromycin derivatives]. 2004 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:15379279
Sun XR et al. [Effect of motilin receptor agonist-erythromycin on the glucose responsive neurons in hypothalamus of rats]. 2005 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21162186