erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Thomas L et al. | Ophthalmic Considerations in Stevens-Johnson Syndrome. | 2016 | J. Pediatr. | pmid:27318376 |
Tang C et al. | The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. | 2016 | Sci Rep | pmid:27897206 |
Sun H et al. | Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. | 2016 | Sci Rep | pmid:27644411 |
Mombelli A et al. | Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci. | 2016 | J. Periodontol. | pmid:26654350 |
Ulanovsky I et al. | Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. | 2016 | Isr. Med. Assoc. J. | pmid:28471562 |
Sagkan-Ozturk A et al. | Prokinetics stimulate the increase of ghrelin in mice. | 2016 | Bratisl Lek Listy | pmid:28127970 |
Caumes E et al. | [Lymphogranuloma venereum]. | 2016 | Ann Dermatol Venereol | pmid:27773504 |
Aslantaş Ö and Demir C | Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. | 2016 | J. Dairy Sci. | pmid:27592437 |
Budha NR et al. | Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. | 2016 | Clin Pharmacokinet | pmid:27225997 |
Ben Salem I et al. | Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. | 2016 | Curr. Microbiol. | pmid:27447798 |
Wu L et al. | Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. | 2016 | PLoS ONE | pmid:27447724 |
Kwon JW | Environmental impact assessment of veterinary drug on fish aquaculture for food safety. | 2016 | Drug Test Anal | pmid:27443211 |
Baker KR et al. | A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. | 2016 | Antimicrob. Agents Chemother. | pmid:27458225 |
Juda M et al. | The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. | 2016 | Mem. Inst. Oswaldo Cruz | pmid:27008373 |
Cui B et al. | Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress. | 2016 | Mol. Genet. Genomics | pmid:27000656 |
Zhang A et al. | Molecular subtyping and erythromycin resistance of Campylobacter in China. | 2016 | J. Appl. Microbiol. | pmid:26999516 |
Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
Sousa M et al. | Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. | 2016 | Microb. Drug Resist. | pmid:26990729 |
Morroni G et al. | Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids. | 2016 | Microb. Drug Resist. | pmid:26982016 |
Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
Barros RR et al. | Polyclonal spread of Streptococcus agalactiae resistant to clindamycin among pregnant women in Brazil. | 2016 | J. Antimicrob. Chemother. | pmid:27029847 |
Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
Gupta P et al. | Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. | 2016 | Nat. Chem. Biol. | pmid:26727240 |
Li J et al. | Rhubarb to Facilitate Placement of Nasojejunal Feeding Tubes in Patients in the Intensive Care Unit. | 2016 | Nutr Clin Pract | pmid:26459161 |
Snoeys J et al. | Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. | 2016 | Clin. Pharmacol. Ther. | pmid:26259716 |
Naik KM and Nandibewoor ST | Investigation into the interaction of methylparaben and erythromycin with human serum albumin using multispectroscopic methods. | 2016 | Luminescence | pmid:26239839 |
Huang M et al. | Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26223917 |
Schneider SC et al. | Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. | 2015 | Antimicrob. Agents Chemother. | pmid:26195516 |
Fayed B et al. | Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. | 2015 | Appl. Environ. Microbiol. | pmid:26431970 |
Wang L et al. | Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. | 2015 | Lett. Appl. Microbiol. | pmid:26031793 |
Wang Z et al. | MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. | 2015 | PLoS ONE | pmid:25706647 |
Yoon IA et al. | Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. | 2015 | Int. J. Infect. Dis. | pmid:26026823 |
Gherardi G et al. | Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. | 2015 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:26024763 |
Reveiz L and Cardona AF | Antibiotics for acute laryngitis in adults. | 2015 | Cochrane Database Syst Rev | pmid:26002823 |
Pesola AK et al. | Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. | 2015 | Euro Surveill. | pmid:25990232 |
Lysnyansky I et al. | Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. | 2015 | Microb. Drug Resist. | pmid:25734368 |
Abreu AC et al. | Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. | 2015 | Microb. Drug Resist. | pmid:25734256 |
Ou H et al. | Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. | 2015 | J. Hazard. Mater. | pmid:25704432 |
Ikebe T et al. | Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. | 2015 | Epidemiol. Infect. | pmid:25703404 |
Chemler JA et al. | Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. | 2015 | J. Am. Chem. Soc. | pmid:26230368 |
Nagelreiter C et al. | Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. | 2015 | Int J Pharm | pmid:25475015 |
Harmer CJ et al. | A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. | 2015 | J. Antimicrob. Chemother. | pmid:25468903 |
Wan J et al. | Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. | 2015 | J. Hazard. Mater. | pmid:25464321 |
Yi X et al. | Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. | 2015 | Anal Bioanal Chem | pmid:26449847 |
Ayazi P et al. | Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. | 2015 | Prague Med Rep | pmid:26445390 |
Yamaguchi M et al. | Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. | 2015 | Cell Rep | pmid:26440893 |
Banik A et al. | Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. | 2015 | J Infect Dev Ctries | pmid:26230122 |
Wang Z et al. | Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. | 2015 | J. Clin. Microbiol. | pmid:26224847 |
Olivieri R et al. | Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. | 2015 | J. Med. Microbiol. | pmid:26224594 |