erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Krokidis MG et al. | Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. | 2014 | Antimicrob. Agents Chemother. | pmid:24189263 |
Goni BW et al. | Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. | 2014 | Trop Doct | pmid:24249028 |
Haworth CS et al. | Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. | 2014 | Respir Med | pmid:25301290 |
Nikolay R et al. | Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. | 2014 | Nucleic Acids Res. | pmid:24792169 |
Sanamrad A et al. | Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25056965 |
Shim J et al. | Clinical inquiry: what is the best treatment for impetigo ? | 2014 | J Fam Pract | pmid:25061625 |
Krishnappa LG et al. | Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. | 2014 | Acta Microbiol Immunol Hung | pmid:24939685 |
Florindo C et al. | Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. | 2014 | Euro Surveill. | pmid:24957747 |
Ye C et al. | Correlation between AcrB trimer association affinity and efflux activity. | 2014 | Biochemistry | pmid:24854514 |
Zhang XF et al. | Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy? | 2014 | Medicine (Baltimore) | pmid:25101987 |
Pierson RC et al. | A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. | 2014 | Obstet Gynecol | pmid:25162251 |
Rozov-Ung I et al. | Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. | 2014 | BMC Gastroenterol | pmid:24383478 |
Miyazaki M et al. | [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. | 2014 | Yakugaku Zasshi | pmid:24492229 |
Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
Pasquini L et al. | Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. | 2014 | Sci. Total Environ. | pmid:24631609 |
Fröhlicher S et al. | Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. | 2014 | Swiss Med Wkly | pmid:24652673 |
Cai HL et al. | Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24424301 |
Khannous L et al. | Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. | 2014 | Lipids Health Dis | pmid:24405763 |
Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
Caierão J et al. | Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. | 2014 | PLoS ONE | pmid:25356595 |
Arenz S et al. | Drug sensing by the ribosome induces translational arrest via active site perturbation. | 2014 | Mol. Cell | pmid:25306253 |
Belén Flórez A et al. | Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. | 2014 | Biomed Res Int | pmid:25302306 |
Wyatt TA et al. | cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. | 2014 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25150062 |
Abarzúa F et al. | [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at ClÃnica Alemana Temuco, Southern Chile]. | 2014 | Rev Chilena Infectol | pmid:25146205 |
Kemp MW et al. | Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. | 2014 | Am. J. Obstet. Gynecol. | pmid:24589547 |
Carls A et al. | Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. | 2014 | Br J Clin Pharmacol | pmid:25139487 |
Zhang Y et al. | [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721407 |
Compain F et al. | Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. | 2014 | Antimicrob. Agents Chemother. | pmid:25136004 |
Hoover WD et al. | Topical antibiotic monotherapy prescribing practices in acne vulgaris. | 2014 | J Dermatolog Treat | pmid:24171409 |
Wagner G et al. | [Childhood granulomatous periorificial dermatitis]. | 2014 | Hautarzt | pmid:25115983 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Johansson M et al. | Sequence-dependent elongation dynamics on macrolide-bound ribosomes. | 2014 | Cell Rep | pmid:24836000 |
Jing YR et al. | The synthesis of novel taxoids for oral administration. | 2014 | Bioorg. Med. Chem. | pmid:24332858 |
Borbón-Esquer EM et al. | SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. | 2014 | Scand. J. Infect. Dis. | pmid:24832853 |
Wang Z et al. | High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. | 2014 | Clin. Microbiol. Infect. | pmid:24816168 |
Allen LN | Mild meningococcaemia, pyrexia protocols and a problematic public health response. | 2014 | BMJ Case Rep | pmid:24811106 |
Mulatu G et al. | Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. | 2014 | Ethiop J Health Sci | pmid:24795510 |
Wu P et al. | SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea. | 2014 | J. Ind. Microbiol. Biotechnol. | pmid:24793123 |
de las Heras MN | Linear IgA bullous dermatosis of childhood: good response to antibiotic treatment. | 2014 | Clin. Exp. Dermatol. | pmid:24772486 |
Dechert-Schmitt AM et al. | Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. | 2014 | Nat Prod Rep | pmid:24514754 |
Benito D et al. | Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. | 2014 | Foodborne Pathog. Dis. | pmid:24479575 |
Boomkamp SD et al. | Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. | 2014 | Br. J. Pharmacol. | pmid:24467222 |
Jun BY et al. | Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. | 2014 | Surg Endosc | pmid:24380989 |
Ren WP et al. | Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. | 2014 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:24347324 |
Brenciani A et al. | Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. | 2014 | J. Antimicrob. Chemother. | pmid:24343896 |
Lu WC et al. | Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. | 2014 | Neurol. Sci. | pmid:24277204 |
Thumu SC and Halami PM | Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. | 2014 | J. Appl. Microbiol. | pmid:24206069 |
Lu B et al. | Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. | 2014 | Clin. Microbiol. Infect. | pmid:24118553 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |