erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rickettsia Infections D012282 5 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Rosacea D012393 13 associated lipids
Rubella D012409 2 associated lipids
Salpingitis D012488 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Scarlet Fever D012541 1 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Seizures D012640 87 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Sialadenitis D012793 1 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Sinusitis D012852 9 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Ulcer D012883 6 associated lipids
Splenic Infarction D013159 1 associated lipids
Splenomegaly D013163 4 associated lipids
Sporotrichosis D013174 3 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Stomach Diseases D013272 7 associated lipids
Stomatitis D013280 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Synovitis D013585 15 associated lipids
Syphilis D013587 6 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Syphilis, Latent D013592 4 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Thromboembolism D013923 6 associated lipids
Thyroid Crisis D013958 1 associated lipids
Onychomycosis D014009 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Tooth Fractures D014082 2 associated lipids
Tooth, Impacted D014095 9 associated lipids
Toothache D014098 3 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Tremor D014202 15 associated lipids
Trench Fever D014205 1 associated lipids
Trisomy D014314 6 associated lipids
Tuberculosis D014376 20 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kudelina RI [Change in the properties of the causative agent of tularemia due to erythromycin]. 1973 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:4785841
Rebrova RN and Serebrennikova II [Fungi of the genus Candida in the diphtheria carrier state]. 1969 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:5382615
Solov'eva SV et al. [Detection of tetracycline- and erythromycin-resistant urogenital Mycoplasma strains using PCR]. 1998 Nov-Dec Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:9949490
Klimchuk ND et al. [Antibiotic sensitivity of the erythromycin-resistant strain E of Rickettsia prowazekii cultured in the vector's body]. 1985 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:3922182
Gamaleia NB and Levashev VS [Biological properties of Salmonella typhimurium mutants with an altered sensitivity to erythromycin]. 1976 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:782116
Wu DQ et al. [The expression of transforming growth factor beta-1 in rat model of chronic obstructive pulmonary disease and the effects of early drugs intervention]. 2004 Zhejiang Da Xue Xue Bao Yi Xue Ban pmid:15476327
Xu G [Regulating effect of electro-acupuncture on dysrythmia of gastro-colonic electric activity induced by erythromycine in rabbits]. 1994 Zhen Ci Yan Jiu pmid:7834859
Wang LQ et al. [Pharmacokinetics of erythromycin stinoprate capsule]. 2005 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:15898434
Lin XM et al. [Influence of neferine and erythromycin on cellular GSH concentration in K562/A02 cell line]. 2004 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:16136961
Xie L et al. [Efficacy of low-dose oral erythromycin as an adjuvant therapy for cytomegalovirus infection]. 2010 Zhongguo Dang Dai Er Ke Za Zhi pmid:20199738
Yang Y [Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. 2008 Zhongguo Dang Dai Er Ke Za Zhi pmid:18289489
Thomas W and Speer CP Prevention and therapy of bronchopulmonary dysplasia - evidence and clinical practice. 2007 Zhongguo Dang Dai Er Ke Za Zhi pmid:17582275
Yu M et al. [Mechanism reversing MDR of K562/A02 by garlicin combined with erythromycin]. 2008 Zhongguo Shi Yan Xue Ye Xue Za Zhi pmid:18928592
Du Y and He Q [The mechanism of alleviation of paraquat induced vascular endothelial permeability by erythromycin through adenosine 3'5'-cyclic monophosphate pathway]. 2009 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:19930884
Lu NF et al. [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]. 2010 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:20092709
Wang H et al. Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:10452125
Huang SK et al. [A combined perfusion-compartmental pharmacokinetic model used to estimate presystemic metabolism of erythromycin in dogs]. 1986 Zhongguo Yao Li Xue Bao pmid:2954396
Ye H et al. Antimycoplasmal activities of (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10 -[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine -6-carboxylic acid (YH-6) in comparison with other antibiotics in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:11270970
Lei PS et al. [Advance in synthesis of ketolides, a new class of erythromycin derivatives]. 2004 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:15379279
Sun XR et al. [Effect of motilin receptor agonist-erythromycin on the glucose responsive neurons in hypothalamus of rats]. 2005 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21162186