erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Kumpfmüller J et al. | Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26432460 |
Thomas L et al. | Ophthalmic Considerations in Stevens-Johnson Syndrome. | 2016 | J. Pediatr. | pmid:27318376 |
Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
Deloose E et al. | Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger. | 2016 | Gut | pmid:25986945 |
Tang C et al. | The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. | 2016 | Sci Rep | pmid:27897206 |
Sun H et al. | Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. | 2016 | Sci Rep | pmid:27644411 |
Mombelli A et al. | Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci. | 2016 | J. Periodontol. | pmid:26654350 |
Ulanovsky I et al. | Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. | 2016 | Isr. Med. Assoc. J. | pmid:28471562 |
Sagkan-Ozturk A et al. | Prokinetics stimulate the increase of ghrelin in mice. | 2016 | Bratisl Lek Listy | pmid:28127970 |
Tack J et al. | Motilin-induced gastric contractions signal hunger in man. | 2016 | Gut | pmid:25539673 |
Hu P et al. | Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. | 2016 | Turk J Gastroenterol | pmid:27782898 |
Heß S and Gallert C | Growth Behavior of E. coli, Enterococcus and Staphylococcus Species in the Presence and Absence of Sub-inhibitory Antibiotic Concentrations: Consequences for Interpretation of Culture-Based Data. | 2016 | Microb. Ecol. | pmid:27220972 |
de Jesus Gaffney V et al. | Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. | 2016 | Environ. Toxicol. Chem. | pmid:27061931 |
Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
Caumes E et al. | [Lymphogranuloma venereum]. | 2016 | Ann Dermatol Venereol | pmid:27773504 |
Aslantaş Ö and Demir C | Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. | 2016 | J. Dairy Sci. | pmid:27592437 |
Budha NR et al. | Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. | 2016 | Clin Pharmacokinet | pmid:27225997 |
Wan TW et al. | Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV. | 2016 | PLoS ONE | pmid:27741255 |
Hadjipanayis A et al. | Nasopharyngeal Pneumococcal Carriage among Healthy Children in Cyprus Post Widespread Simultaneous Implementation of PCV10 and PCV13 Vaccines. | 2016 | PLoS ONE | pmid:27706247 |
Krishnamoorthy G et al. | Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. | 2016 | Antimicrob. Agents Chemother. | pmid:27697764 |
Li M et al. | Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. | 2016 | Int J Mol Sci | pmid:27669217 |
Johanesen P and Lyras D | Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. | 2016 | Methods Mol. Biol. | pmid:27507343 |
Barbanti F et al. | Transfer of Clostridium difficile Genetic Elements Conferring Resistance to Macrolide-Lincosamide-Streptogramin B (MLSB) Antibiotics. | 2016 | Methods Mol. Biol. | pmid:27507342 |
Gaglio R et al. | Evaluation of antimicrobial resistance and virulence of enterococci from equipment surfaces, raw materials, and traditional cheeses. | 2016 | Int. J. Food Microbiol. | pmid:27467501 |
Burr LD et al. | Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. | 2016 | Ann Am Thorac Soc | pmid:27464029 |
Ben Salem I et al. | Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. | 2016 | Curr. Microbiol. | pmid:27447798 |
Wu L et al. | Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. | 2016 | PLoS ONE | pmid:27447724 |
Kwon JW | Environmental impact assessment of veterinary drug on fish aquaculture for food safety. | 2016 | Drug Test Anal | pmid:27443211 |
Aslan Bayhan S et al. | Effects of topical acne treatment on the ocular surface in patients with acne vulgaris. | 2016 | Cont Lens Anterior Eye | pmid:27422575 |
Li X et al. | Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis. | 2016 | Biomed Res Int | pmid:27413745 |
Ababou A and Koronakis V | Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. | 2016 | PLoS ONE | pmid:27403665 |
Yuan QB et al. | Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. | 2016 | Environ Sci Pollut Res Int | pmid:27384166 |
Karlsson E et al. | Clonality of erythromycin resistance in Francisella tularensis. | 2016 | J. Antimicrob. Chemother. | pmid:27334667 |
Changchien CH et al. | Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. | 2016 | BMC Infect. Dis. | pmid:27287530 |
Waiser MJ et al. | Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. | 2016 | Ecotoxicol. Environ. Saf. | pmid:27261880 |
KarniÄar K et al. | Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. | 2016 | Microb. Cell Fact. | pmid:27255285 |
Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
Del Grosso M et al. | ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. | 2016 | Antimicrob. Agents Chemother. | pmid:27067338 |
Aydin S | Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27033714 |
Hsieh PF et al. | The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. | 2016 | Virulence | pmid:27029012 |
Baker KR et al. | A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. | 2016 | Antimicrob. Agents Chemother. | pmid:27458225 |
Juda M et al. | The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. | 2016 | Mem. Inst. Oswaldo Cruz | pmid:27008373 |
Cui B et al. | Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress. | 2016 | Mol. Genet. Genomics | pmid:27000656 |
Lewis K et al. | The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. | 2016 | Crit Care | pmid:27527069 |
Zhang A et al. | Molecular subtyping and erythromycin resistance of Campylobacter in China. | 2016 | J. Appl. Microbiol. | pmid:26999516 |
Pierattini EC et al. | Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. | 2016 | Sci. Total Environ. | pmid:27366984 |
Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
Sousa M et al. | Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. | 2016 | Microb. Drug Resist. | pmid:26990729 |
He HJ et al. | Erythromycin resistance features and biofilm formation affected by subinhibitory erythromycin in clinical isolates of Staphylococcus epidermidis. | 2016 | J Microbiol Immunol Infect | pmid:24768213 |
Bhadra PK et al. | Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. | 2016 | Org. Biomol. Chem. | pmid:27273525 |
Morroni G et al. | Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids. | 2016 | Microb. Drug Resist. | pmid:26982016 |
Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
Lenart-Boroń A et al. | Phenotypic and Molecular Antibiotic Resistance Determination of Airborne Coagulase Negative Staphylococcus spp. Strains from Healthcare Facilities in Southern Poland. | 2016 | Microb. Drug Resist. | pmid:26978225 |
Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
Diawara I et al. | Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco. | 2016 | Infect. Genet. Evol. | pmid:26961592 |
Barros RR et al. | Polyclonal spread of Streptococcus agalactiae resistant to clindamycin among pregnant women in Brazil. | 2016 | J. Antimicrob. Chemother. | pmid:27029847 |
Sierra-Arguello YM et al. | Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. | 2016 | Avian Pathol. | pmid:26925976 |
Molina-Manso D et al. | Effect of different agents with potential antibiofilm activity on antimicrobial susceptibility of biofilms formed by Staphylococcus spp. isolated from implant-related infections. | 2016 | J. Antibiot. | pmid:26905757 |
Meng HL et al. | Construction of polyketide overproducing Escherichia coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis. | 2016 | Biotechnol J | pmid:26709503 |
Madmanang S et al. | Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. | 2016 | J. Nat. Prod. | pmid:26905094 |
Aydin S et al. | Assessment of anaerobic bacterial diversity and its effects on anaerobic system stability and the occurrence of antibiotic resistance genes. | 2016 | Bioresour. Technol. | pmid:26897411 |
Jin Y et al. | From the Cover: Exposure to Oral Antibiotics Induces Gut Microbiota Dysbiosis Associated with Lipid Metabolism Dysfunction and Low-Grade Inflammation in Mice. | 2016 | Toxicol. Sci. | pmid:27503388 |
Pan M and Chu LM | Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. | 2016 | Ecotoxicol. Environ. Saf. | pmid:26773832 |
Rodrigues S et al. | Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. | 2016 | Sci. Total Environ. | pmid:26760278 |
Cheng Y et al. | Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. | 2016 | Anal Bioanal Chem | pmid:26753969 |
Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
Gupta P et al. | Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. | 2016 | Nat. Chem. Biol. | pmid:26727240 |
Dréno B | Bacteriological resistance in acne: A call to action. | 2016 | Eur J Dermatol | pmid:26711531 |
Parhizgari N et al. | High frequency of multidrug-resistant Staphylococcus aureus with SCCmec type III and Spa types t037 and t631 isolated from burn patients in southwest of Iran. | 2016 | APMIS | pmid:26709106 |
Chuang MC et al. | Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. | 2016 | J. Formos. Med. Assoc. | pmid:26705139 |
Broad J et al. | RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions. | 2016 | J. Pharmacol. Sci. | pmid:26685754 |
Sayed Ahmed WA et al. | Maternal serum interleukin-6 in the management of patients with preterm premature rupture of membranes. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26669630 |
Arenz S et al. | A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. | 2016 | Nat Commun | pmid:27380950 |
Berg L et al. | [Cutaneous diphtheria after a minor injury in Sri Lanka]. | 2016 | Hautarzt | pmid:26525966 |
Takahashi T et al. | Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. | 2016 | Ann Lab Med | pmid:26522753 |
Li J et al. | Rhubarb to Facilitate Placement of Nasojejunal Feeding Tubes in Patients in the Intensive Care Unit. | 2016 | Nutr Clin Pract | pmid:26459161 |
Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
Vitali LA et al. | Correlation between genetic features of the mef(A)-msr(D) locus and erythromycin resistance in Streptococcus pyogenes. | 2016 | Diagn. Microbiol. Infect. Dis. | pmid:26429294 |
Feuillolay C et al. | A Myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of Propionibacterium acnes biofilms to antibiotics used in acne vulgaris. | 2016 | Phytomedicine | pmid:26969384 |
Snoeys J et al. | Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. | 2016 | Clin. Pharmacol. Ther. | pmid:26259716 |
Naik KM and Nandibewoor ST | Investigation into the interaction of methylparaben and erythromycin with human serum albumin using multispectroscopic methods. | 2016 | Luminescence | pmid:26239839 |
Pérez RA et al. | Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. | 2017 | J Pharm Biomed Anal | pmid:28858671 |
Zankari E et al. | PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. | 2017 | J. Antimicrob. Chemother. | pmid:29091202 |
Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
Liu J et al. | Interaction of erythromycin and ketoconazole on the neurological, biochemical and behavioral responses in crucian carp. | 2017 | Environ. Toxicol. Pharmacol. | pmid:28802958 |
Cluver C et al. | Interventions for treating genital Chlamydia trachomatis infection in pregnancy. | 2017 | Cochrane Database Syst Rev | pmid:28937705 |
Liu J et al. | Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. | 2017 | Environ Sci Pollut Res Int | pmid:28004371 |
Hillitt KL et al. | Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. | 2017 | Lett. Appl. Microbiol. | pmid:27992658 |
Numanović F et al. | Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria. | 2017 | Med Glas (Zenica) | pmid:27917849 |
Parthasarathy G et al. | Relationship Between Gastric Emptying and Diurnal Glycemic Control in Type 1 Diabetes Mellitus: A Randomized Trial. | 2017 | J. Clin. Endocrinol. Metab. | pmid:27880079 |
Lim SK et al. | Macrolide resistance mechanisms and virulence factors in erythromycin-resistant Campylobacter species isolated from chicken and swine feces and carcasses. | 2017 | J. Vet. Med. Sci. | pmid:27593510 |
Bitew A et al. | Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. | 2017 | BMC Infect. Dis. | pmid:28962545 |
Öksüz L and Gürler N | [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. | 2017 | Mikrobiyol Bul | pmid:28929957 |
Pan M and Chu LM | Transfer of antibiotics from wastewater or animal manure to soil and edible crops. | 2017 | Environ. Pollut. | pmid:28866424 |
Wekselman I et al. | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. | 2017 | Structure | pmid:28689968 |
Truong-Bolduc QC et al. | Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. | 2017 | Antimicrob. Agents Chemother. | pmid:28584148 |
Blackwell GA and Hall RM | The Determinant and the Genes in Acinetobacter Plasmids Are Each Part of Discrete Modules Flanked by Inversely Oriented p (XerC-XerD) Sites. | 2017 | Antimicrob. Agents Chemother. | pmid:28533235 |
Zhou Z et al. | Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. | 2017 | Front Cell Infect Microbiol | pmid:28884090 |
Peng Z et al. | Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale. | 2017 | Microbiologyopen | pmid:28799224 |
Dreno B et al. | Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. | 2017 | Exp. Dermatol. | pmid:28094874 |