erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Pawlowski AC et al. | The evolution of substrate discrimination in macrolide antibiotic resistance enzymes. | 2018 | Nat Commun | pmid:29317655 |
Ababou A | New insights into the structural and functional involvement of the gate loop in AcrB export activity. | 2018 | Biochim. Biophys. Acta | pmid:29126836 |
Li A et al. | Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug-Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers. | 2018 | Paediatr Drugs | pmid:29098603 |
Zhang M et al. | Co-selection of antibiotic resistance via copper shock loading on bacteria from a drinking water bio-filter. | 2018 | Environ. Pollut. | pmid:29059628 |
Tapia C et al. | 2018 | Rev Chilena Infectol | pmid:29912257 | |
Jaén-Gil A et al. | An automated on-line turbulent flow liquid-chromatography technology coupled to a high resolution mass spectrometer LTQ-Orbitrap for suspect screening of antibiotic transformation products during microalgae wastewater treatment. | 2018 | J Chromatogr A | pmid:29910089 |
Kulesa A et al. | Combinatorial drug discovery in nanoliter droplets. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29899149 |
Ersoy B et al. | The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. | 2018 | J Laryngol Otol | pmid:29888693 |
Nishina T et al. | [A case of relapsed neurosyphilis with progressive left hemiparesis]. | 2018 | Rinsho Shinkeigaku | pmid:29863099 |
Zhang Z et al. | The pathogenic and antimicrobial characteristics of an emerging Streptococcus agalactiae serotype IX in Tilapia. | 2018 | Microb. Pathog. | pmid:29859291 |
Zhou P et al. | Cellular metabolism network of Bacillus thuringiensis related to erythromycin stress and degradation. | 2018 | Ecotoxicol. Environ. Saf. | pmid:29857237 |
Azrad M et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli: comparison between Etest and a broth dilution method. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29792197 |
Patil BN and Taranath TC | Limonia acidissima L. leaf mediated synthesis of silver and zinc oxide nanoparticles and their antibacterial activities. | 2018 | Microb. Pathog. | pmid:29248515 |
Ramos CJ et al. | The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. | 2018 | J. Biol. Chem. | pmid:29158262 |
Dias-Souza MV et al. | Euterpe oleracea pulp extract: Chemical analyses, antibiofilm activity against Staphylococcus aureus, cytotoxicity and interference on the activity of antimicrobial drugs. | 2018 | Microb. Pathog. | pmid:29146496 |
Cao Q et al. | Haemophilus parasuis CpxRA two-component system confers bacterial tolerance to environmental stresses and macrolide resistance. | 2018 | Microbiol. Res. | pmid:29146255 |
Kasey CM et al. | Development of Transcription Factor-Based Designer Macrolide Biosensors for Metabolic Engineering and Synthetic Biology. | 2018 | ACS Synth Biol | pmid:28950701 |
Schafhauser BH et al. | Global review and analysis of erythromycin in the environment: Occurrence, bioaccumulation and antibiotic resistance hazards. | 2018 | Environ. Pollut. | pmid:29587215 |
Kleinert C et al. | T lymphocyte-proliferative responses of harbor seal (Phoca vitulina) peripheral blood mononuclear cells (PBMCs) exposed to pharmaceuticals in vitro. | 2018 | Mar. Pollut. Bull. | pmid:29475659 |
Chen CJ et al. | Clinical and molecular features of MDR livestock-associated MRSA ST9 with staphylococcal cassette chromosome mecXII in humans. | 2018 | J. Antimicrob. Chemother. | pmid:29048488 |