erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Labyrinth Diseases D007759 3 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Nie XP et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. 2013 Environ. Pollut. pmid:22982550
Li YJ et al. EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. 2013 Pulm Pharmacol Ther pmid:23291319
Berghaus LJ et al. Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. 2013 Vet. Microbiol. pmid:23915992
Janssen P et al. The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. 2013 Am. J. Gastroenterol. pmid:24005344
Parrott N et al. An unusual cause of persistent postpartum vaginal discharge. 2013 Int J STD AIDS pmid:23970614
Pelchovich G et al. The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. 2013 Int. J. Med. Microbiol. pmid:23972615
Ishihara K et al. Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. 2013 Microbiol. Immunol. pmid:23930694
Pedersen JM et al. Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). 2013 Toxicol. Sci. pmid:24014644
Hirano E et al. Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. 2013 Int. J. Cardiol. pmid:22727964
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). 2013 J. Fish Dis. pmid:24118016
Sripriya J et al. Laser receptive polyelectrolyte thin films doped with biosynthesized silver nanoparticles for antibacterial coatings and drug delivery applications. 2013 Int J Pharm pmid:24096301
Wang HB et al. Molecular epidemiological analysis of group A Streptococci isolated from children in Chaoyang District of Beijing, 2011: emm types, virulence factor genes and erythromycin resistant genes. 2013 Biomed. Environ. Sci. pmid:24099615
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Kelley C et al. Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. 2013 Eur J Med Chem pmid:23314053
González-Pleiter M et al. Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: implications for environmental risk assessment. 2013 Water Res. pmid:23399078
Odhav A et al. Subconjunctival latex paint from occupational injury. 2013 J Emerg Med pmid:23399395
Ziesenitz VC et al. Cytochrome P450-3A phenotyping using midazolam is not altered by OATP1B1 polymorphisms. 2013 Clin. Pharmacol. Ther. pmid:23549145
Kirm B et al. SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. 2013 Microb. Cell Fact. pmid:24341557
Chen Y et al. Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. 2013 Bioresour. Technol. pmid:23500575
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Basak R and Bandyopadhyay R Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. 2013 Langmuir pmid:23472840
Broad J and Sanger GJ The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. 2013 Br. J. Pharmacol. pmid:23190027
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Yang J et al. Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. 2013 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:23474502
Zhang Q et al. High-resolution melting analysis for the detection of two erythromycin-resistant Bordetella pertussis strains carried by healthy schoolchildren in China. 2013 Clin. Microbiol. Infect. pmid:23480481
Prabu D and Menon T Genotyping of erythromycin resistant group C & G streptococci isolated in Chennai, south India. 2013 Indian J. Med. Res. pmid:23481067
Zhang Y et al. Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23481648
Koulaouzidis A et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. 2013 Curr Med Res Opin pmid:23790243
Sundermann U et al. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. 2013 ACS Chem. Biol. pmid:23181268
Chen Y et al. Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. 2013 Bioprocess Biosyst Eng pmid:23361182
Hinarejos P et al. The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. 2013 J Bone Joint Surg Am pmid:23636182
Roberts DW What is the role of antibiotic-containing cement in total knee arthroplasty? 2013 J Bone Joint Surg Am pmid:23636201
Sun W et al. [Glycosyl isomerization based on the biosynthesis of natural-product sugar from microorganism]. 2013 Yao Xue Xue Bao pmid:23672013
Wang H et al. High prevalence of fluoroquinolone-resistant group B streptococci among clinical isolates in China and predominance of sequence type 19 with serotype III. 2013 Antimicrob. Agents Chemother. pmid:23295933
Everson GT et al. Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy. 2013 Liver Transpl. pmid:23239552
Kelmer G et al. Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses. 2013 J. Vet. Pharmacol. Ther. pmid:23240633
Pelchovich G et al. Effect of ribosome-targeting antibiotics on streptomycin-resistant Mycobacterium mutants in the rpsL gene. 2013 Int. J. Antimicrob. Agents pmid:23664678
Oplinger RW and Wagner EJ Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. 2013 J. Aquat. Anim. Health pmid:23241009
Li N et al. Effect of corilagin on membrane permeability of Escherichia coli, Staphylococcus aureus and Candida albicans. 2013 Phytother Res pmid:23192753
Chae HS et al. Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate. 2013 Appl. Environ. Microbiol. pmid:23241984
Marcellin E et al. Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. 2013 BMC Genomics pmid:23324121
Romeiro FG et al. Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study. 2013 BMC Gastroenterol pmid:23324408
Elens L et al. Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin. 2013 Pharmacogenet. Genomics pmid:23324807
Boutouyrie-Dumont B An aide memoire for model-based drug development--a new key for the interpretation of the erythromycin breath test--therapeutic index as a biomarker for smart drug development. 2013 Biomark Med pmid:23387489
Liang JH et al. Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. 2013 Bioorg. Med. Chem. Lett. pmid:23375796
Drago L et al. Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. 2013 Int. J. Antimicrob. Agents pmid:23313535
Gómez-Sanz E et al. Analysis of a novel erm(T)- and cadDX-carrying plasmid from methicillin-susceptible Staphylococcus aureus ST398-t571 of human origin. 2013 J. Antimicrob. Chemother. pmid:23075692
Serisier DJ et al. Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. 2013 JAMA pmid:23532242
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247
Chan BC et al. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. 2013 Phytomedicine pmid:23541215