erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Labyrinth Diseases D007759 3 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Gunes N et al. Erythromycin residue in honey from the Southern Marmara region of Turkey. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:19680838
Weidlich M et al. Differential activity profiles of translation inhibitors in whole-cell and cell-free approaches. 2008 Lett. Appl. Microbiol. pmid:18028330
Flamaing J et al. Pneumococcal bacteraemia in Belgium (1994 2004): the pre-conjugate vaccine era. 2008 J. Antimicrob. Chemother. pmid:17999974
Lai X et al. Evaluation of poly(styrene-alt-maleic anhydride)-ethanol as enteric coating material. 2008 Int J Pharm pmid:18054184
Wolter N et al. Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. 2008 Antimicrob. Agents Chemother. pmid:18056269
Zhu W et al. Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. 2008 Antimicrob. Agents Chemother. pmid:18056272
Onoma M et al. Oral mitemcinal (GM-611), an erythromycin-derived prokinetic, accelerates normal and experimentally delayed gastric emptying in conscious dogs. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18047625
Camilli R et al. New genetic element carrying the erythromycin resistance determinant erm(TR) in Streptococcus pneumoniae. 2008 Antimicrob. Agents Chemother. pmid:18070957
He Z et al. Suppression of oxidant-induced glutathione synthesis by erythromycin in human bronchial epithelial cells. 2008 Respiration pmid:18032881
Merino Díaz L et al. Prevalence and mechanisms of erythromycin and clindamycin resistance in clinical isolates of beta-haemolytic streptococci of Lancefield groups A, B, C and G in Seville, Spain. 2008 Clin. Microbiol. Infect. pmid:18034859
Lopanik NB et al. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. 2008 Chem. Biol. pmid:19022178
Sánchez-Tatay D et al. Antibiotic susceptibility and molecular epidemiology of nasopharyngeal pneumococci from Spanish children. 2008 Clin. Microbiol. Infect. pmid:18727804
Stathi A et al. Prevalence of emm types 1 and 12 from invasive Streptococcus pyogenes disease in Greece--results of enhanced surveillance. 2008 Clin. Microbiol. Infect. pmid:18727807
Yao S et al. Erythromycin-induced ribosome stalling and RNase J1-mediated mRNA processing in Bacillus subtilis. 2008 Mol. Microbiol. pmid:18647167
Basnet DB et al. Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics. 2008 J. Biotechnol. pmid:18430483
Lin CC et al. Effect of erythromycin on bronchial hyperreactivity and inflammation in ovalbumin-sensitized brown Norway rats. 2008 Respir Physiol Neurobiol pmid:18430615
Tinley C et al. Pseudodendritic keratitis in children. 2008 Eye (Lond) pmid:18188170
Römer M et al. Phase transformation of erythromycin A dihydrate during fluid bed drying. 2008 J Pharm Sci pmid:18200525
Elevi Bardavid R and Oren A Sensitivity of Haloquadratum and Salinibacter to antibiotics and other inhibitors: implications for the assessment of the contribution of Archaea and Bacteria to heterotrophic activities in hypersaline environments. 2008 FEMS Microbiol. Ecol. pmid:18205815
Anderson JF et al. Antibiotic resistance of enterococci in American bison (Bison bison) from a nature preserve compared to that of Enterococci in pastured cattle. 2008 Appl. Environ. Microbiol. pmid:18245252
Rasi A et al. Oral erythromycin is ineffective in the treatment of pityriasis rosea. 2008 J Drugs Dermatol pmid:18246696
Takakuwa O et al. [Successful macrolide therapy for recurrent pneumococcal pneumonia in a man with X-linked agammaglobulinemia]. 2008 Nihon Kokyuki Gakkai Zasshi pmid:18260305
Gul HC et al. Macrolide-lincosamide-streptogramin B resistant phenotypes and genotypes for methicillin-resistant Staphylococcus aureus in Turkey, from 2003 to 2006. 2008 Pol. J. Microbiol. pmid:19275044
Onuki H et al. Chemical constituents and diversity of Ligularia lankongensis in Yunnan Province of China. 2008 J. Nat. Prod. pmid:18260639
Gentry DR and Holmes DJ Selection for high-level telithromycin resistance in Staphylococcus aureus yields mutants resulting from an rplB-to-rplV gene conversion-like event. 2008 Antimicrob. Agents Chemother. pmid:18195060
Banche G et al. In vitro compared activity of telithromycin and azithromycin against northwest Italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility. 2008 Lett. Appl. Microbiol. pmid:19241525
Yogo K et al. Effects of oral mitemcinal (GM-611), erythromycin, EM-574 and cisapride on gastric emptying in conscious rhesus monkeys. 2008 Dig. Dis. Sci. pmid:17934842
Miroshnyk I et al. A new insight into solid-state conformation of macrolide antibiotics. 2008 Bioorg. Med. Chem. pmid:17936632
Purdy S and Deberker D Acne vulgaris. 2008 BMJ Clin Evid pmid:19450306
Wang Y et al. High frequency transformation of the industrial erythromycin-producing bacterium Saccharopolyspora erythraea. 2008 Biotechnol. Lett. pmid:17922209
Achard A et al. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. 2008 Antimicrob. Agents Chemother. pmid:18519724
Hutson PR et al. Effect of medical castration on CYP3A4 enzyme activity using the erythromycin breath test. 2008 Cancer Chemother. Pharmacol. pmid:17922273
Yasuda K et al. A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine. 2008 Drug Metab. Dispos. pmid:18505790
Schwaiger K and Bauer J Detection of the erythromycin rRNA methylase gene erm(A) in Enterococcus faecalis. 2008 Antimicrob. Agents Chemother. pmid:18505854
Caldwell DB et al. Development, stability, and molecular mechanisms of macrolide resistance in Campylobacter jejuni. 2008 Antimicrob. Agents Chemother. pmid:18779354
Vartzelis G et al. Lemierre's syndrome and defensive antibiotic prescribing tactics: lessons to be had. 2008 Clin Pediatr (Phila) pmid:18509153
Franke RM et al. Influence of solute carriers on the pharmacokinetics of CYP3A4 probes. 2008 Clin. Pharmacol. Ther. pmid:18509328
Huang G et al. [Rapid detection of oxacillin and erythromycin resistance genes in Staphylococcus aureus using multiplex PCR]. 2008 Nan Fang Yi Ke Da Xue Xue Bao pmid:18495583
Wahab HA et al. Refinement of a low-resolution crystal structure to better understand erythromycin interactions on large ribosomal subunit. 2008 J. Biomol. Struct. Dyn. pmid:18533733
Saha S et al. Enhancement of the efficacy of erythromycin in multiple antibiotic-resistant gram-negative bacterial pathogens. 2008 J. Appl. Microbiol. pmid:18452533
Li D et al. Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model. 2008 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:17826359
Hyo Y et al. Characteristic cell wall ultrastructure of a macrolide-resistant Staphylococcus capitis strain isolated from a patient with chronic sinusitis. 2008 Med Mol Morphol pmid:18807142
Nagano N et al. Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. 2008 Antimicrob. Agents Chemother. pmid:18809936
Reeves AR et al. Knockout of the erythromycin biosynthetic cluster gene, eryBI, blocks isoflavone glucoside bioconversion during erythromycin fermentations in Aeromicrobium erythreum but not in Saccharopolyspora erythraea. 2008 Appl. Environ. Microbiol. pmid:18836015
Gentry DR et al. Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. 2008 Antimicrob. Agents Chemother. pmid:18838584
Gaudreau C et al. Comparison of disk diffusion and agar dilution methods for erythromycin, ciprofloxacin, and tetracycline susceptibility testing of Campylobacter coli and for tetracycline susceptibility testing of Campylobacter jejuni subsp. jejuni. 2008 Antimicrob. Agents Chemother. pmid:18838597
Balassoulis G et al. Efficacy and safety of erythromycin as sclerosing agent in patients with recurrent malignant pleural effusion. 2008 Am. J. Clin. Oncol. pmid:18845999
Kim JM et al. Gene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients. 2008 J. Microbiol. Biotechnol. pmid:18852516
Tamura A et al. The effects of antibiotics on in vitro biofilm model of periodontal disease. 2008 Eur. J. Med. Res. pmid:18948236
Inman JC et al. Pediatric neck abscesses: changing organisms and empiric therapies. 2008 Laryngoscope pmid:18948832
Kennedy J Hidradenitis suppurativa: a diagnostic dilemma for sexual health. 2008 N. Z. Med. J. pmid:18791629
Oda M et al. Effect of erythromycin on biological activities induced by clostridium perfringens alpha-toxin. 2008 J. Pharmacol. Exp. Ther. pmid:18794379
Appendino G et al. Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. 2008 J. Nat. Prod. pmid:18681481
Chng C et al. A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18685110
Palusińska-Szysz M and Cendrowska-Pinkosz M [Occurrence and pathogenicity of the family of Legionellaceae]. 2008 Postepy Hig Med Dosw (Online) pmid:18633335
Sadeghi-Khomami A et al. Glycosidase inhibition by macrolide antibiotics elucidated by STD-NMR spectroscopy. 2008 Chem. Biol. pmid:18635010
Koenig JB et al. Use of multichannel electrointestinography for noninvasive assessment of myoelectrical activity in the cecum and large colon of horses. 2008 Am. J. Vet. Res. pmid:18518649
Hung SW et al. Antibiotic susceptibility and prevalence of erythromycin ribosomal methylase gene, erm(B) in Streptococcus spp. 2008 Vet. J. pmid:17400007
Miller AA et al. Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. 2008 Antimicrob. Agents Chemother. pmid:18519725
Nishino K et al. The AraC-family regulator GadX enhances multidrug resistance in Escherichia coli by activating expression of mdtEF multidrug efflux genes. 2008 J. Infect. Chemother. pmid:18297445
De Munain JL et al. Two lymphogranuloma venereum cases in a heterosexual couple in Bilbao (Spain). 2008 Sex Transm Dis pmid:18641534
Lordan JT et al. An investigative technique to distinguish between the gastrojejunostomy and the hepaticojejunostomy as the cause of cholangitis following pancreaticoduodenectomy. 2008 Ann R Coll Surg Engl pmid:18642429
Horner P Chlamydia (uncomplicated, genital). 2008 BMJ Clin Evid pmid:19450291
Min YH et al. Translational attenuation and mRNA stabilization as mechanisms of erm(B) induction by erythromycin. 2008 Antimicrob. Agents Chemother. pmid:18299414
Wolff BJ et al. Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. 2008 Antimicrob. Agents Chemother. pmid:18644962
Ng E and Shah VS Erythromycin for the prevention and treatment of feeding intolerance in preterm infants. 2008 Cochrane Database Syst Rev pmid:18646077
Hernould M et al. Role of the AheABC efflux pump in Aeromonas hydrophila intrinsic multidrug resistance. 2008 Antimicrob. Agents Chemother. pmid:18268083
Farran L et al. Efficacy of enteral decontamination in the prevention of anastomotic dehiscence and pulmonary infection in esophagogastric surgery. 2008 Dis. Esophagus pmid:18269652
Gallerani M and Boari B Hallucinations and tremors due to oral therapeutic doses of erythromycin and methylprednisolone. 2008 Intern Emerg Med pmid:18270792
Lawrence L et al. In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. 2008 Antimicrob. Agents Chemother. pmid:18316525
Portilla-Arias JA et al. Synthesis, degradability, and drug releasing properties of methyl esters of fungal poly(beta,L-malic acid). 2008 Macromol Biosci pmid:18322913
Auw-Hädrich C [From dry eye to keratitis. Often overlooked: ocular rosacea] [interview by Waldtraud Paukstadt]. 2008 MMW Fortschr Med pmid:18323337
Kennedy W Case of the month. Pitted keratolysis. 2008 JAAPA pmid:18323358
Jeyaraj D et al. I(Kr) channel blockade to unmask occult congenital long QT syndrome. 2008 Heart Rhythm pmid:18273958
Keatinge-Clay A Crystal structure of the erythromycin polyketide synthase dehydratase. 2008 J. Mol. Biol. pmid:18952099
Wang Y and Pfeifer BA 6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli. 2008 Metab. Eng. pmid:17959404
Andreis U et al. Gastric motility evaluated by electrogastrography and alternating current biosusceptometry in dogs. 2008 Physiol Meas pmid:18698113
Perrin MJ et al. Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels. 2008 Mol. Pharmacol. pmid:18701618
Bergseng H et al. Invasive group B streptococcus (GBS) disease in Norway 1996-2006. 2008 Eur. J. Clin. Microbiol. Infect. Dis. pmid:18560908
Waites KB et al. Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. 2008 Antimicrob. Agents Chemother. pmid:18663020
Bukhari IA Oral erythromycin is ineffective in the treatment of pityriasis rosea. 2008 J Drugs Dermatol pmid:18664152
Lin S et al. A school-based program for control of group a streptococcal upper respiratory tract infections: a controlled trial in Southern China. 2008 Pediatr. Infect. Dis. J. pmid:18664988
Kim JS et al. Differential effects of temperature on natural transformation to erythromycin and nalidixic acid resistance in Campylobacter coli. 2008 Appl. Environ. Microbiol. pmid:18708520
de la Pedrosa EG et al. Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). 2008 Antimicrob. Agents Chemother. pmid:18362188
Zou X et al. Application of oxygen uptake rate and response surface methodology for erythromycin production by Saccharopolyspora erythraea. 2008 J. Ind. Microbiol. Biotechnol. pmid:18709395
Higashide M et al. Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. 2008 Antimicrob. Agents Chemother. pmid:18362191
Jones-Caballero M et al. Self-reported adherence to treatment and quality of life in mild to moderate acne. 2008 Dermatology (Basel) pmid:18714158
Urich SK and Petersen JM In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. 2008 Antimicrob. Agents Chemother. pmid:18411318
Zmantar T et al. Multiplex PCR detection of the antibiotic resistance genes in Staphylococcus aureus strains isolated from auricular infections. 2008 Folia Microbiol. (Praha) pmid:18759121
Laohavaleeson S et al. Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. 2008 Antimicrob. Agents Chemother. pmid:18411322
Warner DM et al. Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness. 2008 Mol. Microbiol. pmid:18761689
Hsieh YC et al. Clonal spread of highly beta-lactam-resistant Streptococcus pneumoniae isolates in Taiwan. 2008 Antimicrob. Agents Chemother. pmid:18413298
Bala I et al. Effect of preoperative oral erythromycin, erythromycin-ranitidine, and ranitidine-metoclopramide on gastric fluid pH and volume. 2008 J Clin Anesth pmid:18346606
Nishio N et al. Cat scratch disease with encephalopathy in a 9-year-old girl. 2008 Pediatr Int pmid:19067901
John T and Shah AA Use of azithromycin ophthalmic solution in the treatment of chronic mixed anterior blepharitis. 2008 Ann Ophthalmol (Skokie) pmid:19013912
Kirtsreesakul V et al. Microbiology and antimicrobial susceptibility patterns of commensal flora in the middle nasal meatus. 2008 Ann. Otol. Rhinol. Laryngol. pmid:19140538
Watanabe K et al. Drug-resistant pneumococci in children with acute lower respiratory infections in Vietnam. 2008 Pediatr Int pmid:19143975
Wang C et al. Non-fusion and fusion expression of beta-galactosidase from Lactobacillus bulgaricus in Lactococcus lactis. 2008 Biomed. Environ. Sci. pmid:19133612
Neureiter D et al. Differential diagnostic challenge of chronic neutrophilic leukemia in a patient with prolonged leukocytosis. 2008 J Hematop pmid:19669201
Petropoulos AD et al. Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. 2008 J. Biol. Chem. pmid:18079110