| MeSH term | MeSH ID | Detail |
|---|---|---|
| Labyrinth Diseases | D007759 | 3 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Endocarditis, Bacterial | D004697 | 5 associated lipids |
| Staphylococcal Infections | D013203 | 15 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
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|---|---|---|---|---|
| Zhang W et al. | Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. | 2011 | Curr. Microbiol. | pmid:20924584 |
| Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
| Stang EM and White MC | On the macrocyclization of the erythromycin core: preorganization is not required. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21344559 |
| Fessler AT et al. | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:20876371 |
| Vadlapatla RK et al. | Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin. | 2011 | Int J Pharm | pmid:21864659 |
| Saderi H et al. | Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran. | 2011 | Med. Sci. Monit. | pmid:21278685 |
| Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
| Zhang Q et al. | Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. | 2011 | Lett. Appl. Microbiol. | pmid:21175699 |
| Spigaglia P et al. | Multidrug resistance in European Clostridium difficile clinical isolates. | 2011 | J. Antimicrob. Chemother. | pmid:21771851 |
| Lam HS and Ng PC | Use of prokinetics in the preterm infant. | 2011 | Curr. Opin. Pediatr. | pmid:21178622 |
| Jupelli M et al. | Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. | 2011 | Lab. Invest. | pmid:21769086 |
| Clifford V et al. | Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian group B streptococcus isolates. | 2011 | Aust N Z J Obstet Gynaecol | pmid:21806568 |
| Ma S et al. | Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. | 2011 | Eur J Med Chem | pmid:21159410 |
| Mak PJ et al. | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. | 2011 | J. Am. Chem. Soc. | pmid:21207936 |
| Drago L et al. | Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. | 2011 | J. Microbiol. | pmid:21887650 |
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