erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Tally FP et al. | Clindamycin resistance in anaerobic bacteria. | 1984 | Scand J Infect Dis Suppl | pmid:6598519 |
Nord CE and Heimdahl A | Impact of different antimicrobial agents on the colonisation resistance in the intestinal tract with special reference to doxycycline. | 1988 | Scand J Infect Dis Suppl | pmid:3166543 |
Short-Course Therapy: Improved Patient Compliance and Therapeutic Benefit. Proceedings of a symposium at the 5th European Congress of Clinical Microbiology and Infectious Diseases. Oslo, Norway, 9-11 September 1991. | 1992 | Scand J Infect Dis Suppl | pmid:1362621 | |
Møller BR et al. | Occurrence of Ureaplasma urealyticus and Mycoplasma hominis in non-gonococcal urethritis before and after treatment in a double-blind trial of ofloxacin versus erythromycin. | 1990 | Scand J Infect Dis Suppl | pmid:2218419 |
Rylander M and Hallander HO | In vitro comparison of the activity of doxycycline, tetracycline, erythromycin and a new macrolide, CP 62993, against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum. | 1988 | Scand J Infect Dis Suppl | pmid:2843982 |
Louie EK et al. | IgG-mediated haemolysis masquerading as cold agglutinin-induced anaemia complicating severe infection with mycoplasma pneumoniae. | 1985 | Scand J Haematol | pmid:3933104 |
Pajukanta R et al. | In vitro antimicrobial susceptibility of different serotypes of Actinobacillus actinomycetemcomitans. | 1993 | Scand J Dent Res | pmid:8248732 |
Levin G and Behrenth E | Irreversible ototoxic effect of erythromycin. | 1986 | Scand Audiol | pmid:3704541 |
LUST M and HERBAUT M | [Possible action of erythromycin on reticuloendothelioma in a 12 year-old girl]. | 1956 | Scalpel (Brux) | pmid:13408931 |
Kader AA et al. | Induction of clindamycin resistance in erythromycin-resistant, clindamycin susceptible and methicillin-resistant clinical Staphylococcal isolates. | 2005 | Saudi Med J | pmid:16380772 |
Suliman MT | Toxic epidermal necrolysis due to co-trimoxazole. | 2006 | Saudi Med J | pmid:16432608 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Azuma A et al. | Prolonged survival of a bare lymphocyte syndrome type I patient with diffuse panbronchiolitis treated with erythromycin. | 2001 | Sarcoidosis Vasc Diffuse Lung Dis | pmid:11587107 |
Poletti V et al. | Idiopathic bronchiolitis mimicking diffuse panbronchiolitis. | 2003 | Sarcoidosis Vasc Diffuse Lung Dis | pmid:12737282 |
Cheftel E et al. | [Toxic food infection caused by Shigella flexneri in a military unit]. | 1997 Sep-Oct | Sante | pmid:9480034 |
Anderson KL | Genetic manipulation of anaerobic cellulolytic bacteria. | 1997 | SAAS Bull. Biochem. Biotechnol. | pmid:9274059 |
Straughan J | Erythromycin-carbamazepine interaction? | 1982 | S. Afr. Med. J. | pmid:7064016 |
Horwitz M et al. | Streptococcal pharyngitis and systemic lupus erythematosus. | 1966 | S. Afr. Med. J. | pmid:4959385 |
Robins-Browne RM et al. | Antibiotic susceptibility of Neisseria gonorrhoeae isolated in Johannesburg. | 1978 | S. Afr. Med. J. | pmid:154172 |
Swerdlow J | Ilosone advertisement. | 1978 | S. Afr. Med. J. | pmid:741321 |
Froese EH | Another look at erythromycin. | 1978 | S. Afr. Med. J. | pmid:705532 |
Burgin S and Spencer DC | Bacillary angiomatosis--another South African case. | 1996 | S. Afr. Med. J. | pmid:8685799 |
Kessler JM | Erythromycin-carbamazepine interaction. | 1985 | S. Afr. Med. J. | pmid:4012473 |
Stringer E et al. | Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth. | 2010 | S. Afr. Med. J. | pmid:20429491 |
Straughan JL | Another look at erythromycin. | 1978 | S. Afr. Med. J. | pmid:354037 |
Burdon DW and Keighley MR | Ceftriaxone and metronidazole as single-dose prophylaxis in colorectal surgery. | 1987 | S. Afr. Med. J. | pmid:3603255 |
Weltman MD et al. | Treatment of tick-bite fever in pregnancy. | 1987 | S. Afr. Med. J. | pmid:3603279 |
Kiss A et al. | Misdiagnosed bacillary angiomatosis. | 2007 | S. Afr. Med. J. | pmid:18254198 |
Govender S et al. | Antibiotic susceptibility patterns of Neisseria gonorrhoeae isolates in Port Elizabeth. | 2006 | S. Afr. Med. J. | pmid:16607434 |
Mayosi BM | Protocols for antibiotic use in primary and secondary prevention of rheumatic fever. | 2006 | S. Afr. Med. J. | pmid:16607439 |
Davis WG and White CE | Cloxacillin-resistant Staphylococcus aureus in a children's hospital. | 1974 | S. Afr. Med. J. | pmid:4846427 |
Straughan JL and Anderson R | Erythromycin--three decades later. | 1983 | S. Afr. Med. J. | pmid:6348968 |
Miller GB and Gear JH | Treatment of tick-bite fever with erythromycin. | 1984 | S. Afr. Med. J. | pmid:6548581 |
Adno J | Teeth discoloration and enamelhypoplasia caused by erythromycin. | 1965 | S. Afr. Med. J. | pmid:5859134 |
Huebner RE et al. | Prevalence of nasopharyngeal antibiotic-resistant pneumococcal carriage in children attending private paediatric practices in Johannesburg. | 2000 | S. Afr. Med. J. | pmid:11196033 |
Tanih NF et al. | Marked susceptibility of South African Helicobacter pylori strains to ciprofloxacin and amoxicillin: clinical implications. | 2010 | S. Afr. Med. J. | pmid:20429489 |
Alberti RL | Teeth discoloration and enamel hypoplasia caused by erythromycin. | 1968 | S. Afr. Med. J. | pmid:5647172 |
Levy GR and Nayler S | Bacillary angiomatosis. The first case reported in South Africa. | 1993 | S. Afr. Med. J. | pmid:7839220 |
Wasas AD et al. | Correlation between erythromycin and azithromycin resistance in Streptococcus pneumoniae. | 2003 | S. Afr. Med. J. | pmid:12806721 |
Botha P | Relative erythromycin resistance in Streptococcus pyogenes. | 1990 | S. Afr. Med. J. | pmid:2187256 |
Watson KC | Laboratory evaluation of erythromycin in a general hospital. | 1969 | S. Afr. Med. J. | pmid:4389248 |
Lund RJ et al. | Prophylaxis against gonococcal ophthalmia neonatorum. A prospective study. | 1987 | S. Afr. Med. J. | pmid:3686300 |
Learmonth ID et al. | Acute osteomyelitis and septic arthritis in children. A simple approach to treatment. | 1984 | S. Afr. Med. J. | pmid:6695263 |
Charlton RW | Recent advances in antibiotics. | 1969 | S. Afr. Med. J. | pmid:4305557 |
Rezkalla MA and Pochop C | Erythromycin induced Torsades de Pointes: case report and review of the literature. | 1994 | S D J Med | pmid:8047870 |
Takasugi K | [Lyme disease]. | 1986 | Ryumachi | pmid:3110978 |
Sagara H | [Campylobacter enteritis]. | 1999 | Ryoikibetsu Shokogun Shirizu | pmid:10088324 |
Nakata K | [Diffuse panbronchiolitis (DPB)]. | 1999 | Ryoikibetsu Shokogun Shirizu | pmid:10088434 |
VYMOLA F and HEJZLAR M | [ON THE PROBLEM OF DETERMINATION OF BACTERIAL SENSITIVITY TO ANTIBIOTICS IN VITRO]. | 1963 | Rozhl Chir | pmid:14058700 |
Vanĕk I et al. | [Preventive antibiotics in vascular surgery: 25 years' experience at the Surgical Research Institute of Clinical and Experimental Medicine]. | 1984 | Rozhl Chir | pmid:6719284 |
Pană M et al. | The in vitro susceptibility to 7 antibiotics of Neisseria meningitidis strains isolated last years in Romania. | 2009 Jan-Mar | Roum Arch Microbiol Immunol | pmid:19507626 |
Stark P | [Legionnaire's disease--a puzzling pneumonic illness (author's transl)]. | 1981 | Rofo | pmid:6212331 |
Burzyńska H and Stec E | [Preliminary study of bacterial resistance to antibiotics isolated from food products]. | 1980 | Rocz Panstw Zakl Hig | pmid:6774403 |
Rutczyńska-Skonieczna EM | [Detection of erythromycin residues in poultry meat]. | 1977 | Rocz Panstw Zakl Hig | pmid:565531 |
Lindsay AE and Truxal AC | Oral therapy in bacterial endocarditis. | 1968 | Rocky Mt Med J | pmid:4967211 |
Pokkunuri I and Champney WS | Characteristics of a 50S ribosomal subunit precursor particle as a substrate for ermE methyltransferase activity and erythromycin binding in Staphylococcus aureus. | 2007 | RNA Biol | pmid:18094627 |
Tsagkalia A et al. | Ribosomes containing mutants of L4 ribosomal protein from Thermus thermophilus display multiple defects in ribosomal functions and sensitivity against erythromycin. | 2005 | RNA | pmid:16244130 |
Bommakanti AS et al. | Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae. | 2008 | RNA | pmid:18218702 |
Rodriguez-Correa D and Dahlberg AE | Genetic evidence against the 16S ribosomal RNA helix 27 conformational switch model. | 2004 | RNA | pmid:14681582 |
Siibak T and Remme J | Subribosomal particle analysis reveals the stages of bacterial ribosome assembly at which rRNA nucleotides are modified. | 2010 | RNA | pmid:20719918 |
Zhang Y et al. | Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae. | 2000 | RNA | pmid:10917591 |
Everett D | For a child with pneumonia, there's no place like home. | 1990 | RN | pmid:2315627 |
Schweon S | Whooping cough makes its return. | 2005 | RN | pmid:15736770 |
ERMIGLIA G and VASSALLO E | [First findings in the use of erythromycin in obstetrics and gynecology]. | 1954 | Riv Patol Clin | pmid:14358496 |
Forabosco A | [Preventive treatment with erythromycin in the extraction of impacted 3rd molars]. | 1983 Jul-Aug | Riv Odontostomatol Implantoprotesi | pmid:6583609 |
Dericoloso A et al. | Clarithromycin in the treatment of bacterial relapses of chronic bronchitis. | 1991 Sep-Dec | Riv Eur Sci Med Farmacol | pmid:1840282 |
VANNUCCHI V | [Clinical study of a new antibiotic; erythromycin]. | 1952 | Riv Crit Clin Med | pmid:13056483 |
VANNUCCHI V | [Ilotycin sulfa: association of ilotycin with a trisulfonamide]. | 1953 | Riv Crit Clin Med | pmid:14358369 |
PARADISO M and BORGHERESI S | [Erythromycin]. | 1954 | Riv Clin Pediatr | pmid:13195449 |
PAVARI E and RAGGI GC | [NEURAXITIS FROM CHICKENPOX: CLINICAL AND THERAPEUTIC CONTRIBUTION]. | 1963 | Riv Clin Pediatr | pmid:14076990 |
CASINIRAGGI G and BRANDIGI L | [ON THE ASSOCIATION OF THE LAURYL SULFATE OF ERYTHROMYCIN PROPIONATE WITH DEMETHYLCHLORTETRACYCLINE]. | 1963 | Riv Clin Pediatr | pmid:14080263 |
Nishina T et al. | [A case of relapsed neurosyphilis with progressive left hemiparesis]. | 2018 | Rinsho Shinkeigaku | pmid:29863099 |
Moriyasu H et al. | [Erythromycin-induced hearing loss in a patient with Listeria monocytogenes meningo-ventriculitis]. | 1996 | Rinsho Shinkeigaku | pmid:8976138 |
Uyama E et al. | [A case of HTLV-1 associated myelopathy progressed in course over 30 years]. | 1991 | Rinsho Shinkeigaku | pmid:1893670 |
Fujiwara H et al. | [Pure red cell aplasia induced by erythromycin and furosemide effects on in vitro erythroid colony forming unit (CFU-E)]. | 1994 | Rinsho Ketsueki | pmid:8065024 |
ISHIDA K | [Studies on the ophthalmic use of erythromycin and its derivatives. I. Erythromycin propionate]. | 1961 | Rinsho Ganka | pmid:13717984 |
ISHIDA K | [On the effect of erythromycin combined with a few other antibiotics]. | 1963 | Rinsho Ganka | pmid:13956806 |
ISHIDA K | [Studies on erythromycin and its derivatives. III. On ocular penetration]. | 1963 | Rinsho Ganka | pmid:13956808 |
ISHIDA K | [OCULAR PENETRATION OF ERYTHROMYCIN AFTER LOCAL ADMINISTRATION]. | 1963 | Rinsho Ganka | pmid:14094177 |
MOMOSE A et al. | [4-YEAR RESULTS AND CHANGES IN THE SENSITIVITY TEST OF ORGANISMS ISOLATED FROM THE PUS OF HORDEOLUM]. | 1964 | Rinsho Ganka | pmid:14138998 |
Sawatari K et al. | [Legionella pneumophila infection]. | 1985 | Rinsho Byori | pmid:3897662 |
Osada F et al. | [Staphylococci isolated from clinical sources. 2. Comparison of antibiotic sensitivities of coagulase-positive and coagulase-negative staphylococci]. | 1972 | Rinsho Byori | pmid:4486055 |
Sano I et al. | [Legionellosis]. | 1990 | Rinsho Byori | pmid:2273566 |
Tanamachi C et al. | [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. | 2011 | Rinsho Byori | pmid:21706860 |
Kanno T and Uchida T | [Examples of drug interaction on biochemical analysis (author's transl)]. | 1974 | Rinsho Byori | pmid:4473602 |
Uchida M et al. | [Interference by drugs in the determination of urinary 17-hydroxycorticosteroid (17-OHCS) inhibition of color reaction in Porter-Silber reaction]. | 1971 | Rinsho Byori | pmid:5167925 |
PANCALDO A and BRIGUGLIO FS | [The treatment of subacute bacterial endocarditis with erythromycin]. | 1955 | Riforma Med | pmid:13267302 |
CASSANO A et al. | [Erythromycin in therapy of human brucellosis]. | 1954 | Riforma Med | pmid:13216011 |
SCIOLI C | [Clinical and biological study of an antibiotic combination of demethylchlortetracycline and erythromycin laurylsulfate propionate]. | 1962 | Riforma Med | pmid:13992466 |
DOGLIOTTI GC et al. | [CHRONIC PYELONEPHRITIS]. | 1963 | Riforma Med | pmid:14105760 |
Pekkanen PS | Acute bronchitis-efficacy of erythromycin base (Ery-Max) administered twice or four times daily. | 1983 | Rhinology | pmid:6857107 |
Cervin A and Wallwork B | Macrolide therapy of chronic rhinosinusitis. | 2007 | Rhinology | pmid:18085018 |
Inamura K et al. | The effects of erythromycin on human peripheral neutrophil apoptosis. | 2000 | Rhinology | pmid:11072658 |
Qvarnberg Y et al. | Influence of topical steroid treatment on maxillary sinusitis. | 1992 | Rhinology | pmid:1411095 |
Moriyama H et al. | Evaluation of endoscopic sinus surgery for chronic sinusitis: post-operative erythromycin therapy. | 1995 | Rhinology | pmid:8560171 |
von Sydow C et al. | Treatment of acute maxillary sinusitis. Erythromycin base and phenoxymethyl-penicillin (penicillin V). | 1984 | Rhinology | pmid:6441236 |
Elmorsy S et al. | Sinus aspirates in chronic rhinosinusitis: fungal colonization of paranasal sinuses, evaluation of ICAM-1 and IL-8 and studying of immunological effect of long-term macrolide therapy. | 2010 | Rhinology | pmid:21038022 |
Bradlow A et al. | Group G streptococcal arthritis. | 1982 | Rheumatol Rehabil | pmid:7134741 |
Justa RF et al. | Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. | 2011 | Rev. Soc. Bras. Med. Trop. | pmid:22031085 |