erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Multiple D000015 13 associated lipids
Bradycardia D001919 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Urticaria D014581 13 associated lipids
Critical Illness D016638 13 associated lipids
Uveitis D014605 14 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Stomatitis D013280 14 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Neutropenia D009503 15 associated lipids
Synovitis D013585 15 associated lipids
Tremor D014202 15 associated lipids
Blister D001768 16 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Cholelithiasis D002769 16 associated lipids
Choline Deficiency D002796 16 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Ischemia D007511 18 associated lipids
Leishmaniasis D007896 19 associated lipids
Hypothermia D007035 19 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Ataxia D001259 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Pleurisy D010998 20 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Tuberculosis D014376 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Vomiting D014839 21 associated lipids
Hypersensitivity D006967 22 associated lipids
Periodontitis D010518 22 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Nasal Polyps D009298 26 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Obesity D009765 29 associated lipids
Dermatitis D003872 30 associated lipids
Drug Eruptions D003875 30 associated lipids
Liver Diseases D008107 31 associated lipids
Cardiomegaly D006332 31 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
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Sanamrad A et al. Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25056965
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Krishnappa LG et al. Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. 2014 Acta Microbiol Immunol Hung pmid:24939685
Florindo C et al. Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. 2014 Euro Surveill. pmid:24957747
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Pierson RC et al. A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. 2014 Obstet Gynecol pmid:25162251
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Fröhlicher S et al. Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. 2014 Swiss Med Wkly pmid:24652673
Cai HL et al. Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. 2014 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:24424301
Caierão J et al. Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. 2014 PLoS ONE pmid:25356595
Arenz S et al. Drug sensing by the ribosome induces translational arrest via active site perturbation. 2014 Mol. Cell pmid:25306253
Wyatt TA et al. cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. 2014 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25150062
Abarzúa F et al. [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at Clínica Alemana Temuco, Southern Chile]. 2014 Rev Chilena Infectol pmid:25146205
Carls A et al. Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. 2014 Br J Clin Pharmacol pmid:25139487
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Piccinelli G et al. In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. 2014 Antimicrob. Agents Chemother. pmid:24379197
Ramos FL and Criner GJ Use of long-term macrolide therapy in chronic obstructive pulmonary disease. 2014 Curr Opin Pulm Med pmid:24378875
Johansson M et al. Sequence-dependent elongation dynamics on macrolide-bound ribosomes. 2014 Cell Rep pmid:24836000
Jing YR et al. The synthesis of novel taxoids for oral administration. 2014 Bioorg. Med. Chem. pmid:24332858
Borbón-Esquer EM et al. SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. 2014 Scand. J. Infect. Dis. pmid:24832853
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Allen LN Mild meningococcaemia, pyrexia protocols and a problematic public health response. 2014 BMJ Case Rep pmid:24811106
Mulatu G et al. Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. 2014 Ethiop J Health Sci pmid:24795510
Dechert-Schmitt AM et al. Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. 2014 Nat Prod Rep pmid:24514754
Montes M et al. What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. 2014 J. Antimicrob. Chemother. pmid:24562616
Benito D et al. Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. 2014 Foodborne Pathog. Dis. pmid:24479575
Boomkamp SD et al. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. 2014 Br. J. Pharmacol. pmid:24467222
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989
Ren WP et al. Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. 2014 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:24347324
Brenciani A et al. Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. 2014 J. Antimicrob. Chemother. pmid:24343896
Lu WC et al. Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. 2014 Neurol. Sci. pmid:24277204
Mazumdar G and Shome K Stevens-Johnson syndrome following use of metronidazole in a dental patient. 2014 Jan-Feb Indian J Pharmacol pmid:24550598
Patti MG Erythromycin Use Before Induction of General Endotracheal Anesthesia. 2015 JAMA Surg pmid:26083012
Zhu Y et al. Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". 2015 Sci Rep pmid:25791905
Wang P et al. Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. 2015 PLoS ONE pmid:25781346
Zhou Y et al. Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. 2015 Talanta pmid:25770599
Gardiner SJ et al. Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. 2015 Cochrane Database Syst Rev pmid:25566754
Azadegan A et al. Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. 2015 Ann Lab Med pmid:25553281
Wu H et al. Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. 2015 Appl. Microbiol. Biotechnol. pmid:25549616
Hawkins PA et al. Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. 2015 Microb. Drug Resist. pmid:25115711
Vallianou N et al. Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. 2015 J Chemother pmid:25112954
Pavlova A and Gumbart JC Parametrization of macrolide antibiotics using the force field toolkit. 2015 J Comput Chem pmid:26280362
Daghighi S et al. Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. 2015 Int. J. Antimicrob. Agents pmid:26526893
Bravo-Rodriguez K et al. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. 2015 Chem. Biol. pmid:26526102
Bolukaoto JY et al. Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. 2015 BMC Res Notes pmid:26289147