erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Corneal Diseases D003316 13 associated lipids
Abscess D000038 13 associated lipids
Multiple Myeloma D009101 13 associated lipids
Rosacea D012393 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Stomatitis D013280 14 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Uveitis D014605 14 associated lipids
Synovitis D013585 15 associated lipids
Tremor D014202 15 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Neutropenia D009503 15 associated lipids
Cholelithiasis D002769 16 associated lipids
Choline Deficiency D002796 16 associated lipids
Blister D001768 16 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Ischemia D007511 18 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leishmaniasis D007896 19 associated lipids
Hypothermia D007035 19 associated lipids
Pleurisy D010998 20 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Tuberculosis D014376 20 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Ataxia D001259 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Vomiting D014839 21 associated lipids
Periodontitis D010518 22 associated lipids
Hypersensitivity D006967 22 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Nasal Polyps D009298 26 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Obesity D009765 29 associated lipids
Drug Eruptions D003875 30 associated lipids
Dermatitis D003872 30 associated lipids
Cardiomegaly D006332 31 associated lipids
Liver Diseases D008107 31 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Chen C et al. Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:27709326
Gonser LI et al. Systemic therapy of ocular and cutaneous rosacea in children. 2017 J Eur Acad Dermatol Venereol pmid:28621909
Mingmongkolchai S and Panbangred W In vitro evaluation of candidate Bacillus spp. for animal feed. 2017 J. Gen. Appl. Microbiol. pmid:28331163
Attaran B et al. Effect of biofilm formation by clinical isolates of on the efflux-mediated resistance to commonly used antibiotics. 2017 World J. Gastroenterol. pmid:28275296
Nowakiewicz A et al. Determination of antimicrobial resistance of Enterococcus strains isolated from pigs and their genotypic characterization by method of amplification of DNA fragments surrounding rare restriction sites (ADSRRS fingerprinting). 2017 J. Med. Microbiol. pmid:28260584
Hodge S et al. Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28258107
Lee JH et al. Genetic Diversity and Antibiotic Resistance of Enterococcus faecalis Isolates from Traditional Korean Fermented Soybean Foods. 2017 J. Microbiol. Biotechnol. pmid:28237994
Descours G et al. Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. 2017 Antimicrob. Agents Chemother. pmid:28069647
Wei L et al. Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. 2017 J Environ Sci (China) pmid:28115128
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Sugimoto N et al. Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. 2017 BMC Res Notes pmid:28057059
Kullin B et al. Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27696234
Pavlović D et al. Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. 2017 Eur J Med Chem pmid:27657812
Naimi HM et al. Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. 2017 BMC Infect. Dis. pmid:29187146
Ricker EB and Nuxoll E Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. 2017 Biofouling pmid:29039211
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Wang B et al. Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. 2017 J. Dairy Sci. pmid:28987584
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551
Zhao L et al. Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. 2017 J Sep Sci pmid:28121061
Murchison L et al. Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. 2016 Pediatr. Surg. Int. pmid:27655365