erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Goni BW et al. | Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. | 2014 | Trop Doct | pmid:24249028 |
Sadeghi J and Mansouri S | Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). | 2014 | APMIS | pmid:24033803 |
Haworth CS et al. | Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. | 2014 | Respir Med | pmid:25301290 |
Ye C et al. | Correlation between AcrB trimer association affinity and efflux activity. | 2014 | Biochemistry | pmid:24854514 |
Zhang XF et al. | Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy? | 2014 | Medicine (Baltimore) | pmid:25101987 |
Blattner C et al. | A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. | 2014 | J. Cutan. Pathol. | pmid:24588271 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. | 2014 | Antimicrob. Agents Chemother. | pmid:24449773 |
Barbosa TM et al. | A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. | 2014 | PLoS ONE | pmid:25548909 |
Hudson BH and Zaher HS | Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. | 2014 | Mol. Cell | pmid:25514181 |
Pinto TC et al. | Conjugative transfer of resistance determinants among human and bovine Streptococcus agalactiae. | 2014 | Braz. J. Microbiol. | pmid:25477908 |
Cai HL et al. | Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24424301 |
Khannous L et al. | Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. | 2014 | Lipids Health Dis | pmid:24405763 |
Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
Leirós M et al. | Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. | 2014 | ACS Chem Neurosci | pmid:24219236 |
Arenz S et al. | Drug sensing by the ribosome induces translational arrest via active site perturbation. | 2014 | Mol. Cell | pmid:25306253 |
Belén Flórez A et al. | Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. | 2014 | Biomed Res Int | pmid:25302306 |
Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
Farabella I et al. | Allosteric signalling in the outer membrane translocation domain of PapC usher. | 2014 | Elife | pmid:25271373 |
Jaiswal N et al. | Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. | 2014 | PLoS ONE | pmid:25268974 |
Katayama Y et al. | Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. | 2014 | Brain Res. | pmid:25264351 |
Bauer CA and Grimme S | First principles calculation of electron ionization mass spectra for selected organic drug molecules. | 2014 | Org. Biomol. Chem. | pmid:25260171 |
Kemp MW et al. | Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. | 2014 | Am. J. Obstet. Gynecol. | pmid:24589547 |
Zhang Y et al. | [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721407 |
Hoover WD et al. | Topical antibiotic monotherapy prescribing practices in acne vulgaris. | 2014 | J Dermatolog Treat | pmid:24171409 |
Wagner G et al. | [Childhood granulomatous periorificial dermatitis]. | 2014 | Hautarzt | pmid:25115983 |
Shen Y et al. | Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. | 2014 | ScientificWorldJournal | pmid:25110723 |
Tagawa J et al. | Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. | 2014 | J. Microbiol. Methods | pmid:25102110 |
Serna-Tamayo C et al. | Neonatal and infantile acne vulgaris: an update. | 2014 | Cutis | pmid:25101339 |
Kinouchi H et al. | Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. | 2014 | Biol. Pharm. Bull. | pmid:25087959 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Mulatu G et al. | Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. | 2014 | Ethiop J Health Sci | pmid:24795510 |
Wu P et al. | SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea. | 2014 | J. Ind. Microbiol. Biotechnol. | pmid:24793123 |
de las Heras MN | Linear IgA bullous dermatosis of childhood: good response to antibiotic treatment. | 2014 | Clin. Exp. Dermatol. | pmid:24772486 |
Kawaguchiya M et al. | Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. | 2014 | Microb. Drug Resist. | pmid:24766085 |
Gaudreau C et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli isolates obtained in Montreal, Quebec, Canada, from 2002 to 2013. | 2014 | J. Clin. Microbiol. | pmid:24759726 |
Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
Murphree CA et al. | Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. | 2014 | Curr. Microbiol. | pmid:24748439 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Brenciani A et al. | Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. | 2014 | J. Antimicrob. Chemother. | pmid:24343896 |
Lu WC et al. | Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. | 2014 | Neurol. Sci. | pmid:24277204 |
Thumu SC and Halami PM | Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. | 2014 | J. Appl. Microbiol. | pmid:24206069 |
Lu B et al. | Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. | 2014 | Clin. Microbiol. Infect. | pmid:24118553 |
Zheng PX et al. | Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. | 2014 | Clin. Microbiol. Infect. | pmid:24118239 |
Singh P et al. | Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. | 2014 | Fundam Clin Pharmacol | pmid:24117516 |
Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. | 2014 | J. Fish Dis. | pmid:23992037 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |