erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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He Z and Li Y | [Diffuse panbronchiolitis]. | 1996 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:9388854 |
Yin YD et al. | [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24503430 |
Huang JQ and Xie CM | [The effects of erythromycin on the secretion of tumor necrosis factor-alpha and transforming growth factor-beta1 and expression of connexin 43 in human pleural mesothelial cells]. | 2003 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:12901826 |
Yu L and Ran PX | [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. | 2009 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:19567187 |
Zhong XN et al. | [An experimental study on airway inflammation and remodeling in a rat model of chronic bronchitis and emphysema]. | 2003 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:14720429 |
Gao W et al. | [Analysis of 9 cases of pulmonary tuberculosis complicated with legionnaires disease]. | 1997 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:10374448 |
Xu Z et al. | [Effects of erythromycin and fosfomycin on Pseudomonas aeruginosa biofilm in vitro]. | 2001 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11802985 |
Gu XH et al. | [Effects of erythromycin on the twitching motility of Pseudomonas aeruginosa]. | 2007 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:17573001 |
Tan W et al. | [The mechanism and effect of erythromycin in development of pulmonary fibrosis]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11812357 |
Tang YC | [Diagnosis and treatment of Legionnaires' disease from opportunistic infection]. | 1987 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:3440298 |