erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Jokinen MJ et al. | The effect of erythromycin, fluvoxamine, and their combination on the pharmacokinetics of ropivacaine. | 2000 | Anesth. Analg. | pmid:11049910 |
Wilkie D | Cytoplasmic inheritance and mitochondrial genetics in yeasts. | 1975 | Methods Cell Biol. | pmid:1105071 |
Guerrini AM et al. | Studies on a temperature sensitive nuclear petite mutant of Saccharomyces cerevisiae: phenotypic reversibility of the mitochondrial functions. | 1975 | Mol. Gen. Genet. | pmid:1105155 |
See S | Is azithromycin monotherapy as efficacious as cefuroxime plus erythromycin for the treatment of community-acquired pneumonia in hospitalized patients? | 2000 | J Fam Pract | pmid:11052155 |
Kazim M et al. | Schizontocidal activity of antibiotics against blood-induced Plasmodium gallinaceum infection. | 1979 | Chemotherapy | pmid:110541 |
Condon RE and Nichols RL | The present position of the neomycin-erythromycin bowal prep. | 1975 | Surg. Clin. North Am. | pmid:1105832 |
Farmer RG | Preoperative preparation of the patients with carcinoma of the colon. | 1975 | Surg. Clin. North Am. | pmid:1105833 |
Mant A | Choosing the most appropriate antibiotic for respiratory infections. | 2000 | Aust Fam Physician | pmid:11059087 |
Vivrette SL et al. | Clinical application of a polymerase chain reaction assay in the diagnosis of pneumonia caused by Rhodococcus equi in a horse. | 2000 | J. Am. Vet. Med. Assoc. | pmid:11061388 |
McCune JS et al. | In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone. | 2000 | Clin. Pharmacol. Ther. | pmid:11061575 |
Lagrou K et al. | Subinhibitory concentrations of erythromycin reduce pneumococcal adherence to respiratory epithelial cells in vitro. | 2000 | J. Antimicrob. Chemother. | pmid:11062190 |
Granizo JJ et al. | Streptococcus pneumoniae resistance to erythromycin and penicillin in relation to macrolide and beta-lactam consumption in Spain (1979-1997). | 2000 | J. Antimicrob. Chemother. | pmid:11062196 |
Kataja J et al. | Erythromycin resistance genes in group A streptococci of different geographical origins. The Macrolide Resistance Study Group. | 2000 | J. Antimicrob. Chemother. | pmid:11062199 |
Okamoto H et al. | Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against gram-positive clinical isolates in Japan. | 2000 | J. Antimicrob. Chemother. | pmid:11062201 |
Kiso S et al. | Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats. | 2000 Sep-Oct | Anticancer Res. | pmid:11062690 |
Buschmann G and Duprée C | [Oral treatment of udder actinomycosis in swine]. | 1976 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:1106993 |
Morikawa T et al. | Superoxide dismutase in alveolar macrophages from patients with diffuse panbronchiolitis. | 2000 | Respiration | pmid:11070461 |
Patole SK et al. | Benefits of a standardised feeding regimen during a clinical trial in preterm neonates. | 2000 | Int. J. Clin. Pract. | pmid:11070566 |
Matsunaga H et al. | Manometric evidence of improved early gastric stasis by erythromycin after pylorus-preserving pancreatoduodenectomy. | 2000 | World J Surg | pmid:11071469 |
Riippi M et al. | Effect of compression force on the crystal properties of erythromycin acistrate tablets. | 2000 | Eur J Pharm Biopharm | pmid:11072193 |
Ranjit K and Nurahan M | Tetracycline resistant cholera in Kelantan. | 2000 | Med. J. Malaysia | pmid:11072502 |
Inamura K et al. | The effects of erythromycin on human peripheral neutrophil apoptosis. | 2000 | Rhinology | pmid:11072658 |
Prueksaritanont T et al. | Simvastatin does not affect CYP3A activity, quantified by the erythromycin breath test and oral midazolam pharmacokinetics, in healthy male subjects. | 2000 | J Clin Pharmacol | pmid:11075313 |
Kuriyama T et al. | Bacteriologic features and antimicrobial susceptibility in isolates from orofacial odontogenic infections. | 2000 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:11077383 |
Weisblum B et al. | Deoxyribonucleic acid sequence common to staphylococcal and streptococcal plasmids which specify erythromycin resistance. | 1979 | J. Bacteriol. | pmid:110774 |
Putrament A et al. | Manganese mutagenesis in yeast. IV. The effects of magnesium, protein synthesis inhibitors and hydroxyurea on AntR induction in mitochondrial DNA. | 1975 | Mol. Gen. Genet. | pmid:1107804 |
Salvatore P et al. | A new vector for insertion of any DNA fragment into the chromosome of transformable Neisseriae. | 2000 | Plasmid | pmid:11078653 |
Ishii T et al. | Improvement in bronchiolitis obliterans organizing pneumonia in a child after allogeneic bone marrow transplantation by a combination of oral prednisolone and low dose erythromycin. | 2000 | Bone Marrow Transplant. | pmid:11081394 |
Singh KV et al. | Efficacy of telithromycin (HMR 3647) against enterococci in a mouse peritonitis model. | 2000 | Antimicrob. Agents Chemother. | pmid:11083653 |
Mikoc A et al. | Construction and characterization of a Streptomyces rimosus recA mutant: the RecA-deficient strain remains viable. | 2000 | Mol. Gen. Genet. | pmid:11085261 |
Gouda H et al. | Three-dimensional structure-activity relationship analysis between motilin and motilide using conformational analysis and a novel molecular superposing method. | 2000 | Chem. Pharm. Bull. | pmid:11086932 |
Corona GJ | Bacterial endocarditis. A brief review. | 1978 | J Macomb Dent Soc | pmid:110894 |
Pantosti A et al. | Antibiotic susceptibility and serotype distribution of Streptococcus pneumoniae causing meningitis in Italy, 1997-1999. | 2000 | Clin. Infect. Dis. | pmid:11096005 |
Giovanetti E et al. | In vitro activity of ketolides telithromycin and HMR 3004 against italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility. | 2000 | J. Antimicrob. Chemother. | pmid:11102408 |
Granizo JJ et al. | Streptococcus pyogenes resistance to erythromycin in relation to macrolide consumption in Spain (1986-1997). | 2000 | J. Antimicrob. Chemother. | pmid:11102415 |
Johansen HK et al. | Antagonism between penicillin and erythromycin against Streptococcus pneumoniae in vitro and in vivo. | 2000 | J. Antimicrob. Chemother. | pmid:11102417 |
Andrews JM et al. | The in vitro activity of ABT773, a new ketolide antimicrobial agent. | 2000 | J. Antimicrob. Chemother. | pmid:11102425 |
Bird PA and Sturgess AD | Clinical ergotism with severe bilateral upper limb ischaemia precipitated by an erythromycin--ergotamine drug interaction. | 2000 | Aust N Z J Med | pmid:11108077 |
Navarro C et al. | [Resistance to penicillin and other antimicrobials in 301 clinical isolates of Streptococcus pneumoniae]. | 2000 Aug-Sep | Enferm. Infecc. Microbiol. Clin. | pmid:11109722 |
Okimoto N et al. | [Influence of macrolide therapy on microorganism of chronic respiratory tract infections]. | 2000 | Kansenshogaku Zasshi | pmid:11109768 |
Bar J et al. | Effect of antibiotic therapy in preterm premature rupture of the membranes on neonatal mortality and morbidity. | 2000 | Am J Perinatol | pmid:11110340 |
Schumacher J et al. | Surgical and medical treatment of an Arabian filly with proliferative enteropathy caused by Lawsonia intracellularis. | 2000 Nov-Dec | J. Vet. Intern. Med. | pmid:11110386 |
Laven RA and Proven MJ | Use of an antibiotic footbath in the treatment of bovine digital dermatitis. | 2000 | Vet. Rec. | pmid:11110490 |
Carević O et al. | Correlation between erythromycin and acid phosphatase in mouse liver. | 1975 | Biochim. Biophys. Acta | pmid:1111590 |
Brennan S et al. | Directed neutrophil migration to IL-8 is increased in cystic fibrosis: a study of the effect of erythromycin. | 2001 | Thorax | pmid:11120907 |
Credito KL et al. | Susceptibilities of Haemophilus influenzae and Moraxella catarrhalis to ABT-773 compared to their susceptibilities to 11 other agents. | 2001 | Antimicrob. Agents Chemother. | pmid:11120946 |
Singh KV et al. | Disruption of an Enterococcus faecium species-specific gene, a homologue of acquired macrolide resistance genes of staphylococci, is associated with an increase in macrolide susceptibility. | 2001 | Antimicrob. Agents Chemother. | pmid:11120975 |
Palavecino EL et al. | Prevalence and mechanisms of macrolide resistance in Streptococcus pyogenes in Santiago, Chile. | 2001 | Antimicrob. Agents Chemother. | pmid:11120993 |
Syrogiannopoulos GA et al. | Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece. | 2001 | Antimicrob. Agents Chemother. | pmid:11120994 |
Citron DM and Appleman MD | Comparative in vitro activities of ABT-773 against 362 clinical isolates of anaerobic bacteria. | 2001 | Antimicrob. Agents Chemother. | pmid:11120995 |
Crespi CL et al. | Analysis of drug transport and metabolism in cell monolayer systems that have been modified by cytochrome P4503A4 cDNA-expression. | 2000 | Eur J Pharm Sci | pmid:11121734 |
McOrist S | Obligate intracellular bacteria and antibiotic resistance. | 2000 | Trends Microbiol. | pmid:11121750 |
Talley NJ et al. | Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121915 |
Meisler DM et al. | Oral erythromycin treatment for childhood blepharokeratitis. | 2000 | J AAPOS | pmid:11124676 |
Moseley BE and Copland HJ | Isolation and properties of a recombination-deficient mutant of Micrococcus radiodurans. | 1975 | J. Bacteriol. | pmid:1112771 |
Murase T et al. | Erythromycin resistance genes in Streptococcus pyogenes isolates in Kanagawa, Japan. | 2000 | Microbiol. Immunol. | pmid:11128071 |
Doumith M et al. | Analysis of genes involved in 6-deoxyhexose biosynthesis and transfer in Saccharopolyspora erythraea. | 2000 | Mol. Gen. Genet. | pmid:11129052 |
Eckman MR et al. | Letter: Partial deafness after erythromycin. | 1975 | N. Engl. J. Med. | pmid:1113753 |
Lukásová J and Jarchovská H | [Resistance of Staphylococcus-aureus strains, isolated from food, to antibiotics]. | 1979 | Vet Med (Praha) | pmid:111401 |
Manzella J et al. | Choice of antibiotic and risk of colonization with vancomycin-resistant Enterococcus among patients admitted for treatment of community-acquired pneumonia. | 2000 | Infect Control Hosp Epidemiol | pmid:11140916 |
Siani MA et al. | Development and screening of a polyketide virtual library for drug leads against a motilide pharmacophore. | 2000 Aug-Oct | J. Mol. Graph. Model. | pmid:11143565 |
Nikulin KG | [Principles of current therapy of acute and chronic pneumonia]. | 1975 | Sov Med | pmid:1114373 |
Shaikh WA | The changing face of antihistamines and cardiac adverse drug reactions: a clinical perspective. | 2000 | J Indian Med Assoc | pmid:11143865 |
Plettenberg A et al. | Bacillary angiomatosis in HIV-infected patients--an epidemiological and clinical study. | 2000 | Dermatology (Basel) | pmid:11146343 |
Rosenthal EJ | [Increase of penicillin-resistant pneumococci in Germany]. | 2000 | Dtsch. Med. Wochenschr. | pmid:11149217 |
Koutsoumbi P et al. | The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. | 2000 | Am. J. Gastroenterol. | pmid:11151866 |
Portincasa P et al. | The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. | 2000 | Am. J. Gastroenterol. | pmid:11151875 |
Piroth L et al. | HMR 3647 human-like treatment of experimental pneumonia due to penicillin-resistant and erythromycin-resistant Streptococcus pneumoniae. | 2001 | J. Antimicrob. Chemother. | pmid:11152429 |
Esposito S et al. | Bactericidal activity of moxifloxacin compared to grepafloxacin and clarithromycin against Streptococcus pneumoniae and Streptococcus pyogenes investigated using an in vitro pharmacodynamic model. | 2000 | J Chemother | pmid:11154028 |
Dahlén G et al. | Identification and antimicrobial susceptibility of enterococci isolated from the root canal. | 2000 | Oral Microbiol. Immunol. | pmid:11154422 |
Komenaka IK et al. | Erythromycin and position facilitated placement of postpyloric feeding tubes in burned patients. | 2000 | Dig Surg | pmid:11155002 |
Muller-Serieys C | [Ketolides and oxazolidinones. Mechanisms of action and antibacterial spectrum]. | 2000 | Presse Med | pmid:11155736 |
Shoemaker NB et al. | Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon. | 2001 | Appl. Environ. Microbiol. | pmid:11157217 |
Silang R et al. | Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. | 2001 | Am. J. Kidney Dis. | pmid:11157368 |
Leblond F et al. | Downregulation of hepatic cytochrome P450 in chronic renal failure. | 2001 | J. Am. Soc. Nephrol. | pmid:11158222 |
Sato E et al. | Erythromycin modulates eosinophil chemotactic cytokine production by human lung fibroblasts in vitro. | 2001 | Antimicrob. Agents Chemother. | pmid:11158732 |
Polk RE et al. | Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy males. | 2001 | Antimicrob. Agents Chemother. | pmid:11158747 |
Yumoto R et al. | Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone. | 2001 | Drug Metab. Dispos. | pmid:11159804 |
Fera MT et al. | Antimicrobial activity and postantibiotic effect of flurithromycin against Helicobacter pylori strains. | 2001 | Int. J. Antimicrob. Agents | pmid:11165121 |
Dam WC et al. | The effect of common antibiotics on lymphocyte transformation. | 1975 | Experientia | pmid:1116556 |
Lotter AM and Allen GW | Recent observations on the bacteriology of tonsillitis. | 1975 | Eye Ear Nose Throat Mon | pmid:1116585 |
Korn SJ et al. | Susceptibility pattern of Streptococcus pneumoniae in outpatients in Germany. | 2000 | Clin. Microbiol. Infect. | pmid:11168054 |
Auckenthaler R et al. | In vitro activity of quinupristin/dalfopristin in comparison with five antibiotics against worldwide clinical isolates of staphylococci. | 2000 | Clin. Microbiol. Infect. | pmid:11168064 |
Felek S et al. | Therapeutic effects of rifampin and erythromycin in experimental murine brucellosis. | 2000 | Clin. Microbiol. Infect. | pmid:11168083 |
Van Assche G et al. | Contractile effects and intracellular Ca2+ signalling induced by motilin and erythromycin in the circular smooth muscle of human colon. | 2001 | Neurogastroenterol. Motil. | pmid:11169123 |
Kuriyama T et al. | Incidence of beta-lactamase production and antimicrobial susceptibility of anaerobic gram-negative rods isolated from pus specimens of orofacial odontogenic infections. | 2001 | Oral Microbiol. Immunol. | pmid:11169133 |
Coles WH | Effects of antibiotics on the in vitro rabbit corneal endothelium. | 1975 | Invest Ophthalmol | pmid:1116924 |
Anstead G et al. | Thermophilic multidrug-resistant Campylobacter fetus infection with hypersplenism and histiocytic phagocytosis in a patient with acquired immunodeficiency syndrome. | 2001 | Clin. Infect. Dis. | pmid:11170921 |
Esposito S et al. | Activity of moxifloxacin and twelve other antimicrobial agents against 216 clinical isolates of Streptococcus pneumoniae. | 2001 Mar-Apr | Chemotherapy | pmid:11173809 |
Lemmen S et al. | In vitro activity of gemifloxacin against Streptococcus pneumoniae isolates in Germany. | 2001 Mar-Apr | Chemotherapy | pmid:11173811 |
Dougherty TJ and Barrett JF | ABT-773: a new ketolide antibiotic. | 2001 | Expert Opin Investig Drugs | pmid:11178346 |
Jalava J et al. | In vitro activities of the novel ketolide telithromycin (HMR 3647) against erythromycin-resistant Streptococcus species. | 2001 | Antimicrob. Agents Chemother. | pmid:11181362 |
Holm EA and Jemec GB | [Acne neonatorum/acne infantum]. | 2000 | Ugeskr. Laeg. | pmid:11187144 |
Soriano SV et al. | [Streptococcus pyogenes: penicillin and erythromycin susceptibility in the cities of Neuquen and Cipolletti]. | 2000 | Medicina (B Aires) | pmid:11188957 |
Yoshida H and Furuta T | [Relationship between the chemical structure of O-methyl erythromycin derivatives and their affinity to the lung]. | 2000 | Jpn J Antibiot | pmid:11190046 |
Shephard RW et al. | A clinical trial to evaluate the effectiveness of antibiotic treatment of lactating cows with high somatic cell counts in their milk. | 2000 | Aust. Vet. J. | pmid:11194722 |
Fenoll A et al. | Streptococcus pneumoniae in children in Spain: 1990-1999. | 2000 | Acta Paediatr Suppl | pmid:11194798 |
Huebner RE et al. | Prevalence of nasopharyngeal antibiotic-resistant pneumococcal carriage in children attending private paediatric practices in Johannesburg. | 2000 | S. Afr. Med. J. | pmid:11196033 |
Seral C et al. | [Presence of conjugative transposon Tn1545 in strains of Streptococcus pneumoniae with mef(A), erm(B), tet(M), catpC194 and aph3'-III genes]. | 2000 | Enferm. Infecc. Microbiol. Clin. | pmid:11198001 |
Patole SK et al. | Can prophylactic oral erythromycin reduce time to full enteral feeds in preterm neonates? | 2000 | Int. J. Clin. Pract. | pmid:11198727 |