erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Halstensen A et al. | [Treatment of infections caused by group A beta-hemolytic streptococci]. | 1990 | Tidsskr. Nor. Laegeforen. | pmid:2120791 |
Gulbrandsen P and Fugelli P | [Bad custom]. | 1991 | Tidsskr. Nor. Laegeforen. | pmid:2000597 |
Nesbakken T et al. | [Chlamydial inclusion conjunctivitis in the newborn. 5 cases]. | 1982 | Tidsskr. Nor. Laegeforen. | pmid:7157283 |
Ose L | [Encephalitis associated with mycoplasma pneumoniae infection in children]. | 1975 | Tidsskr. Nor. Laegeforen. | pmid:1145545 |
Brauteset LV et al. | [Invasive pneumoccal disease in children in Oslo 1998-2004]. | 2008 | Tidsskr. Nor. Laegeforen. | pmid:18552897 |
Volden G | [Syphilis]. | 1980 | Tidsskr. Nor. Laegeforen. | pmid:6992342 |
Afset JE and Maeland JA | [Erythromycin and ciprofloxacin resistant Campylobacter jejuni]. | 2001 | Tidsskr. Nor. Laegeforen. | pmid:11571989 |
Itoh T and Kasahara S | Rat T lymphocyte progenitors in bone marrow can be induced to express more Thy 1. | 1985 | Thymus | pmid:2865831 |
Johnsson H and Niklasson PM | Effects of some antibiotics of platelet function in vitro and in vivo. | 1977 | Thromb. Res. | pmid:905975 |
Yousaf N et al. | Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial. | 2010 | Thorax | pmid:20965928 |
Azuma A et al. | Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. | 1998 | Thorax | pmid:9659353 |
Waterworth PM et al. | A critical investigation into the antibiotic sterilization of heart valve homografts. | 1974 | Thorax | pmid:4368321 |
Dorrell L et al. | Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. | 1994 | Thorax | pmid:8016806 |
White RJ | Why use erythromycin? | 1994 | Thorax | pmid:7974308 |
Oaklay CM | Prevention of infective endocarditis. | 1979 | Thorax | pmid:542909 |
Brennan S et al. | Directed neutrophil migration to IL-8 is increased in cystic fibrosis: a study of the effect of erythromycin. | 2001 | Thorax | pmid:11120907 |
Ellis ME and Dunbar EM | In vivo response of acute Q fever to erythromycin. | 1982 | Thorax | pmid:7164010 |
Domingo C et al. | Radiographic appearance of nosocomial legionnaires' disease after erythromycin treatment. | 1991 | Thorax | pmid:1948796 |
Venkatesan P et al. | A hospital study of community acquired pneumonia in the elderly. | 1990 | Thorax | pmid:2356552 |
Fujii T et al. | Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. | 1995 | Thorax | pmid:8553295 |
Tsang KW et al. | Clinical profiles of Chinese patients with diffuse panbronchiolitis. | 1998 | Thorax | pmid:9741370 |
Guest PJ et al. | Pulmonary Mycobacterium kansasii infection successfully treated with a regimen containing erythromycin. | 1988 | Thorax | pmid:3420563 |
Brugiere O et al. | Diffuse panbronchiolitis in an Asian immigrant. | 1996 | Thorax | pmid:8977613 |
Marlin GE et al. | Plasma and sputum erythromycin concentrations in chronic bronchitis. | 1980 | Thorax | pmid:7434299 |
Koyama H and Geddes DM | Erythromycin and diffuse panbronchiolitis. | 1997 | Thorax | pmid:9404381 |
Sobradillo V et al. | Antibiotic treatment in pneumonia due to Q fever. | 1992 | Thorax | pmid:1585291 |
McCulloch AJ et al. | Severe steroid responsive pneumonitis associated with pyoderma gangrenosum and ulcerative colitis. | 1985 | Thorax | pmid:4023983 |
Rogers GB et al. | Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. | 2013 | Thorax | pmid:23564400 |
GROTHUESMANN HG | [DEVELOPMENT OF RESISTANCE OF PATHOGENIC URINARY BACTERIA TO THE MOST COMMON ANTIBIOTICS]. | 1964 | Therapiewoche | pmid:14143496 |
Lagier G et al. | [A minor case of ergotism appearing to be connected with a potentialisation of ergotamine tartrate by erythromycine ethyl-succinate (author's transl)]. | 1979 Jul-Aug | Therapie | pmid:531783 |
Bergogne-Berezin E et al. | [Experimental study of the possible influence of a fluidifying agent (bromhexine) on the penetration of erythromycine into bronchial secretions (author's transl)]. | 1979 Nov-Dec | Therapie | pmid:547444 |
Baldit C et al. | [Influence of a new macrolide, dirithromycine, on the clearance of antipyrine]. | 1987 May-Jun | Therapie | pmid:3660320 |
Bavoux F | [Torsades de pointes and anti-infective agents]. | 1992 Sep-Oct | Therapie | pmid:1299973 |
VIALLIER J et al. | [Study of the blood levels obtained with 2 new esters of erythromycin: propionyl erythromycin and propionyl erythromycin lauryl sulfate]. | 1961 Nov-Dec | Therapie | pmid:13925737 |
Kanfer A et al. | [Erythromycin ototoxicity in patients with renal insufficiency (author's transl)]. | 1980 May-Jun | Therapie | pmid:7423428 |
Hugues FC et al. | [Cochlear toxicity of erythromycin in elderly patients]. | 1984 Sep-Oct | Therapie | pmid:6506017 |
TREFOUEL J et al. | [Not Available]. | 1959 | Therapie | pmid:13647435 |
Moutard I et al. | In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. | 1999 Sep-Oct | Therapie | pmid:10667098 |
Hoppe JE | [Pertussis: current aspects of diagnosis, therapy and prevention]. | 1998 | Ther Umsch | pmid:9492614 |
Meyer JC and Eichmann A | [Serodiagnosis and therapy of syphilis]. | 1985 | Ther Umsch | pmid:3911474 |
Korting HC | [Urethritis in the male, diagnosis and therapy]. | 1985 | Ther Umsch | pmid:2935962 |
Münnich D et al. | Observations on micro-encapsulated erythromycin (Eryc capsule) in the treatment of various infections of adults. | 1988 | Ther Hung | pmid:3249998 |
Ferencz A et al. | Use of Eryc capsule in adult patients. | 1989 | Ther Hung | pmid:2686082 |
RUBANYI P and KOS R | ACTUAL PROBLEMS OF ANTIBIOTIC TREATMENT IN SURGICAL PRACTICE. | 1963 | Ther Hung | pmid:14133128 |
Adám A and Kuberka Z | Use of a new erythromycin product--eryc--in the treatment of the lower respiratory tract infections. | 1990 | Ther Hung | pmid:2094053 |
FIEGEL G | [The place of erythromycin among the antibiotics]. | 1957 | Ther Ggw | pmid:13422363 |
ILKER HG | [Not Available]. | 1957 | Ther Ggw | pmid:13422370 |
Petzoldt D | [Current diagnosis and therapy of acquired syphilis]. | 1973 | Ther Ggw | pmid:4708581 |
Miles MV and Tennison MB | Erythromycin effects on multiple-dose carbamazepine kinetics. | 1989 | Ther Drug Monit | pmid:2911854 |
Hedrick R et al. | Carbamazepine--erythromycin interaction leading to carbamazepine toxicity in four epileptic children. | 1983 | Ther Drug Monit | pmid:6659014 |
Wadhwa NK et al. | Interaction between erythromycin and cyclosporine in a kidney and pancreas allograft recipient. | 1987 | Ther Drug Monit | pmid:3554626 |
Watkins PB | Erythromycin breath test and clinical transplantation. | 1996 | Ther Drug Monit | pmid:8857552 |
Buiter HJ et al. | Erythromycin precipitation in vena femoralis: investigation of crystals found in postmortem material of an intensive care unit patient. | 2008 | Ther Drug Monit | pmid:18223476 |
Baciewicz AM | Carbamazepine drug interactions. | 1986 | Ther Drug Monit | pmid:3092407 |
Wadhwa NK et al. | Cyclosporine drug interactions: a review. | 1987 | Ther Drug Monit | pmid:3321582 |
Birkett DJ et al. | Single oral dose pharmacokinetics of erythromycin and roxithromycin and the effects of chronic dosing. | 1990 | Ther Drug Monit | pmid:2305423 |
de Wildt SN et al. | 13C-erythromycin breath test as a noninvasive measure of CYP3A activity in newborn infants: a pilot study. | 2007 | Ther Drug Monit | pmid:17417078 |
Padhi ID et al. | Interaction between tacrolimus and erythromycin. | 1997 | Ther Drug Monit | pmid:9029762 |
Luurila H et al. | Lack of interaction of erythromycin with temazepam. | 1994 | Ther Drug Monit | pmid:7878692 |
Henkes M et al. | Therapeutic options for chronic myeloid leukemia: focus on imatinib (Glivec, Gleevectrade mark). | 2008 | Ther Clin Risk Manag | pmid:18728706 |
Enyuan Q et al. | Erythromycin combined with corticosteroid reduced inflammation and modified trauma-induced tracheal stenosis in a rabbit model. | Ther Adv Respir Dis | pmid:29781361 | |
Scherrer K and Jost J | Gene and genon concept: coding versus regulation. A conceptual and information-theoretic analysis of genetic storage and expression in the light of modern molecular biology. | 2007 | Theory Biosci. | pmid:18087760 |
MULLINS JF | Neomycin-erythromycin ointment in the treatment of pyodermas. | 1954 | Tex State J Med | pmid:13169049 |
DELGADO JN and COSGROVE FP | FALLACIES OF GENERIC EQUIVALENCE THESIS. I. SOME PHYSIOLOGIC FACTORS INFLUENCING GASTROINTESTINAL ABSORPTION. | 1963 | Tex Med | pmid:14067239 |
Schweinle JE | Legionnaires' disease. | 1981 | Tex Med | pmid:7245097 |
Farris JR et al. | Chancroid in Dallas: new lessons from an old disease. | 1991 | Tex Med | pmid:1882362 |
Manning RJ | Hemorrhage secondary to Campylobacter enterocolitis: conservative care. | 1986 | Tex Med | pmid:3486490 |
Alexander RE and Grogan DM | Long-acting erythromycins: assessing their role in treating outpatient odontogenic infections. | 2009 | Tex Dent J | pmid:19472551 |
Djokić S and Tamburasĕv Z | Erythromycin study: 9-amino-3-O-cladinosyl-5-O-desosaminyl-6,11,12-tryhydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide. | 1967 | Tetrahedron Lett. | pmid:6047192 |
HARRIS DR et al. | THE STRUCTURE AND STEREOCHEMISTRY OF ERYTHROMYCIN A. | 1965 | Tetrahedron Lett. | pmid:14295195 |
Massey EH et al. | Erythromycylamine. | 1970 | Tetrahedron Lett. | pmid:5416094 |
Demarco PV | Pyridine solvent shifts in the NMR analysis of etythromycin aglycones. | 1969 | Tetrahedron Lett. | pmid:5779748 |
Perun TJ and Egan RS | The conformation of erythromycin aglycones. | 1969 | Tetrahedron Lett. | pmid:5779749 |
Molineaux CJ et al. | Mutagenic activation of an antischistosomal drug by enteric Streptococcus sps in vitro and in vivo. | 1980 | Teratog., Carcinog. Mutagen. | pmid:6119805 |
StrachunskiÄ LS et al. | [Rovamycin (spiramycin)--a macrolide antibiotic for intravenous administration: a trial in the treatment of pneumonia]. | 1995 | Ter. Arkh. | pmid:7770811 |
Milevskaia IuL | [Complex use of tetracycline and erythromycin in the therapy of internal diseases and hematology]. | 1971 | Ter. Arkh. | pmid:5117924 |
VinogradskiÄ OV and Porokhnia NP | [An acute allergic reaction caused by ingestion of erythromycin]. | 1966 | Ter. Arkh. | pmid:5988260 |
VEIS RA and EDEL'SHTEIN SI | [Erythromycin (erythrocin, ilotycin)]. | 1960 | Ter. Arkh. | pmid:13780602 |
OVSIANNIKOVA NP | [Treatment of inflammatory processes of the biliary tract with erythromycin]. | 1963 | Ter. Arkh. | pmid:13940824 |
Potekaev NS et al. | [An unusual variant of secondary recurrent syphilis in an HIV-infected patient]. | 1993 | Ter. Arkh. | pmid:7906439 |
GAVRILINA TN and LAGERT IK | [ERYTHROMYCIN IN THE TREATMENT OF CHRONIC PNEUMONIA]. | 1964 | Ter. Arkh. | pmid:14218793 |
Nikulin KG | [Treatment of acute pneumonia at different stages of the disease]. | 1977 | Ter. Arkh. | pmid:867244 |
RudoÄ NM and Khauadamova GT | [Selection of optimal antibacterial drugs for test therapy in differential diagnosis of pulmonary tuberculosis and pneumonia]. | 1980 | Ter. Arkh. | pmid:6770483 |
Jones TF | Pertussis: challenges and new opportunities for prevention. | 2005 | Tenn Med | pmid:16294570 |
HEDBERG M | QUANTITATIVE STUDY OF BACTERIA IN MIXED POPULATIONS. A SURFACE-PLATING METHOD FOR ENUMERATING, IDENTIFYING, AND DETERMINING ANTIMICROBIAL SUSCEPTIBILITY. | 1964 | Tech Bull Regist Med Technol | pmid:14119126 |
Tanaka H | [Receptor agonists and antagonists: the present and future]. | 1993 | Tanpakushitsu Kakusan Koso | pmid:8210427 |
Omura S et al. | [Motilide, motilin-like macrolides]. | 1993 | Tanpakushitsu Kakusan Koso | pmid:8210432 |
Nakai S | [Genetic repair system in yeast (author's transl)]. | 1974 | Tanpakushitsu Kakusan Koso | pmid:4373789 |
Nashimoto H | [Mutants in ribosome assembly]. | 1972 | Tanpakushitsu Kakusan Koso | pmid:4559521 |
Zhou Y et al. | Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. | 2015 | Talanta | pmid:25770599 |
Sari E et al. | Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. | 2016 | Talanta | pmid:26838449 |
Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
Yeung SW et al. | Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. | 2014 | Taiwan J Obstet Gynecol | pmid:25017269 |
Kroon AM and de Vries H | Antibiotics: a tool in the search for the degree of autonomy of mitochondria in higher animals. | 1970 | Symp. Soc. Exp. Biol. | pmid:5516337 |
Wilkie D | Analysis of mitochondrial drug resistance in Saccharomyces cerevisiae. | 1970 | Symp. Soc. Exp. Biol. | pmid:5516345 |
Losa M et al. | CI (critical incidents) vs. CI (corporate identity). | 2001 | Swiss Med Wkly | pmid:11416892 |
Fröhlicher S et al. | Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. | 2014 | Swiss Med Wkly | pmid:24652673 |
Schöni MH | Macrolide antibiotic therapy in patients with cystic fibrosis. | 2003 | Swiss Med Wkly | pmid:12861467 |
Capanna F et al. | Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. | 2013 | Swiss Med Wkly | pmid:23572445 |
SANTESSON G | [Metastatic lung infiltrate in a case of coli- and staphylococcic septicemia, which was treated with erythromycin and tetracycline]. | 1956 | Sven Lakartidn | pmid:13311778 |