erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Duodenogastric Reflux D004383 2 associated lipids
Duodenitis D004382 4 associated lipids
Dry Socket D004368 3 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Diphtheria D004165 2 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Diarrhea D003967 32 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Drug Eruptions D003875 30 associated lipids
Dermatitis D003872 30 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Death, Sudden D003645 12 associated lipids
Dacryocystitis D003607 1 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cross Infection D003428 9 associated lipids
Crohn Disease D003424 12 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Corneal Diseases D003316 13 associated lipids
Constipation D003248 8 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Conjunctivitis D003231 7 associated lipids
Compartment Syndromes D003161 1 associated lipids
Common Cold D003139 2 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Cleft Palate D002972 9 associated lipids
Chronic Disease D002908 7 associated lipids
Choroiditis D002833 1 associated lipids
Chorioamnionitis D002821 5 associated lipids
Choline Deficiency D002796 16 associated lipids
Cholestasis D002779 23 associated lipids
Cholelithiasis D002769 16 associated lipids
Choanal Atresia D002754 1 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Chancroid D002602 4 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Carbuncle D002270 1 associated lipids
Campylobacter Infections D002169 13 associated lipids
Bursitis D002062 3 associated lipids
Bundle-Branch Block D002037 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Mokhber-Dezfooli MR et al. Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. 2012 J. Dairy Sci. pmid:22981576
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Oo C and Shah B Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? 2012 J Clin Pharmacol pmid:21868717
Sommerfeld Ross S and Fiegel J Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. 2012 Int. J. Antimicrob. Agents pmid:22727773
Zaknoon F et al. Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. 2012 Antimicrob. Agents Chemother. pmid:22751534
García-Pérez ME et al. Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. 2012 Food Chem pmid:22953840
Martins ER et al. Dominance of serotype Ia among group B Streptococci causing invasive infections in nonpregnant adults in Portugal. 2012 J. Clin. Microbiol. pmid:22219307
Shore EM and Yudin MH Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. 2012 J Obstet Gynaecol Can pmid:22385665
Ullrich K et al. Neuroretinitis following bull ant sting. 2012 BMJ Case Rep pmid:22865803
Pinto A et al. 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. 2012 Org. Lett. pmid:22519860
Yuzawa S et al. Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. 2012 Biochemistry pmid:22509729
Wang Y et al. The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. 2012 Beilstein J Org Chem pmid:23019458
Shimizu S et al. Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. 2012 J. Agric. Food Chem. pmid:22694300
Karlgren M et al. Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. 2012 J. Med. Chem. pmid:22541068
Noormohamed A and Fakhr MK Incidence and antimicrobial resistance profiling of Campylobacter in retail chicken livers and gizzards. 2012 Foodborne Pathog. Dis. pmid:22545960
Pinto TF et al. Tolerance to enteral nutrition therapy in traumatic brain injury patients. 2012 Brain Inj pmid:22571511
Deane AM et al. Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. 2012 Am. J. Clin. Nutr. pmid:22572649
Rocco L et al. Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. 2012 Environ. Toxicol. pmid:21384490
Izumikawa M et al. JBIR-78 and JBIR-95: phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56. 2012 J. Nat. Prod. pmid:22264203
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Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
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Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Fessler AT et al. Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. 2011 Antimicrob. Agents Chemother. pmid:20876371
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Otsu K et al. Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. 2011 Pharmacology pmid:22116077
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Hiller NL et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. 2011 PLoS ONE pmid:22205975
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Nielsen EI et al. Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. 2011 Antimicrob. Agents Chemother. pmid:21282424
Belousoff MJ et al. Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21282615
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Saderi H et al. Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran. 2011 Med. Sci. Monit. pmid:21278685
Zhang Q et al. Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. 2011 Lett. Appl. Microbiol. pmid:21175699
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Ma S et al. Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. 2011 Eur J Med Chem pmid:21159410
Mak PJ et al. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. 2011 J. Am. Chem. Soc. pmid:21207936
Chen Y et al. Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. 2011 Drug Metab. Dispos. pmid:21835977
Ahmetagic A et al. Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. 2011 Plasmid pmid:21839110
Zhou L et al. Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. 2011 Vaccine pmid:21839135
Wu J et al. Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. 2011 Appl. Environ. Microbiol. pmid:21841022
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Senthilkumaran S and Subramanian PT Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. 2011 Indian Pediatr pmid:22711153
Sonnevend Á et al. Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. 2011 Scand. J. Infect. Dis. pmid:21905953
Sigaroudinia MO and Quayle AR Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. 2011 Surgeon pmid:21550524
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
Li MJ et al. High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. 2011 Analyst pmid:20944848
Andini N and Nash KA Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. 2011 FEMS Microbiol. Lett. pmid:21718348
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Imperi M et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. 2011 Clin. Microbiol. Infect. pmid:21722258
Wan G et al. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. 2011 Cell. Signal. pmid:21723942
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
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Chen I et al. Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. 2011 J. Clin. Microbiol. pmid:21068284
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Wang SM et al. Clinical significance of erythromycin-resistant Campylobacter jejuni in children. 2011 J Microbiol Immunol Infect pmid:21531355
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
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Kataoka M et al. Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. 2011 Eur J Pharm Sci pmid:21963456
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Gupta R et al. A 14-year-old with rectal bleeding and abdominal pain. 2011 J. Pediatr. Gastroenterol. Nutr. pmid:21970991
Pignatello R et al. Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. 2011 AAPS PharmSciTech pmid:21479751
Keelan JA et al. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. 2011 Am. J. Obstet. Gynecol. pmid:21481833
Fan C and He J Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. 2011 Water Res. pmid:21482429
Franke RM et al. Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. 2011 Clin. Pharmacol. Ther. pmid:21451505
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Zhang Z et al. Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498135
Del Grosso M et al. Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. 2011 Antimicrob. Agents Chemother. pmid:21502613
Loreto ES et al. In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. 2011 Antimicrob. Agents Chemother. pmid:21537028
Nakamura PA et al. Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. 2011 Mem. Inst. Oswaldo Cruz pmid:21537668
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Li Y et al. Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. 2011 J. Appl. Microbiol. pmid:20961364
Vuppalanchi R et al. Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. 2011 J. Clin. Gastroenterol. pmid:20962670