erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Lacrimal Duct Obstruction D007767 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Sporotrichosis D013174 3 associated lipids
Ehrlichiosis D016873 2 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Rubella D012409 2 associated lipids
Pleural Diseases D010995 4 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Erythema Multiforme D004892 3 associated lipids
Prolapse D011391 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
Heart Murmurs D006337 1 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Bartonella Infections D001474 3 associated lipids
Scarlet Fever D012541 1 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Dry Socket D004368 3 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Sialadenitis D012793 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Megacolon D008531 1 associated lipids
Relapsing Fever D012061 3 associated lipids
Carbuncle D002270 1 associated lipids
Furunculosis D005667 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Marfan Syndrome D008382 2 associated lipids
Elephantiasis D004604 2 associated lipids
Lymphangitis D008205 4 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Nakashima R et al. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. 2011 Nature pmid:22121023
Abarzúa F et al. [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. 2011 Rev Chilena Infectol pmid:22052397
Werner CR et al. [Unexpected complication following esophageal variceal hemorrhage - Case 2/2011]. 2011 Dtsch. Med. Wochenschr. pmid:21271486
Hiller NL et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. 2011 PLoS ONE pmid:22205975
Wright AJ et al. The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers. 2011 CMAJ pmid:21242274
Tachecí I et al. Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. 2011 Neuro Endocrinol. Lett. pmid:22167215
Zhang L et al. Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. 2011 J. Antibiot. pmid:21245870
Nielsen EI et al. Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. 2011 Antimicrob. Agents Chemother. pmid:21282424
Belousoff MJ et al. Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21282615
Yuan H et al. [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. 2011 Zhonghua Jie He He Hu Xi Za Zhi pmid:22041779
Spigaglia P et al. Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. 2011 Emerging Infect. Dis. pmid:21291621
Huppertz A et al. Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). 2011 J Magn Reson Imaging pmid:21274983
Vadlapatla RK et al. Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin. 2011 Int J Pharm pmid:21864659
Watanabe I et al. Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. 2011 Int Heart J pmid:22188715
Saderi H et al. Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran. 2011 Med. Sci. Monit. pmid:21278685
Lubell Y et al. Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. 2011 Trop. Med. Int. Health pmid:21740488
Zhang Q et al. Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. 2011 Lett. Appl. Microbiol. pmid:21175699
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Rodríguez C et al. [Resistance phenotypes and genotypes of Streptococcus pyogenes clinical isolates in Chile over a 10-year period]. 2011 Rev Med Chil pmid:22215392
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Liu Y et al. The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. 2011 Bioorg. Med. Chem. Lett. pmid:21570844
Samra Z et al. Susceptibility of Ureaplasma urealyticum to tetracycline, doxycycline, erythromycin, roxithromycin, clarithromycin, azithromycin, levofloxacin and moxifloxacin. 2011 J Chemother pmid:21571622
Sonnevend Á et al. Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. 2011 Scand. J. Infect. Dis. pmid:21905953
Bistrian BR Enteral feeding: good, but not for everyone. 2011 Crit. Care Med. pmid:21613857
Bai Y et al. Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. 2011 Aliment. Pharmacol. Ther. pmid:21615438
Jessick AM et al. Optimization of analytical methods to improve detection of erythromycin from water and sediment. 2011 J Environ Sci Health B pmid:21877980
Ergin A et al. Erythromycin and penicillin resistance mechanisms among viridans group streptococci isolated from blood cultures of adult patients with underlying diseases. 2011 New Microbiol. pmid:21617831
Lee CY et al. Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. 2011 Implant Dent pmid:21881516
Garber NC et al. Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. 2011 Adv. Exp. Med. Biol. pmid:21618111
Tazi A et al. Invasive group B streptococcal infections in adults, France (2007-2010). 2011 Clin. Microbiol. Infect. pmid:21883671
Sugiyama E et al. The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. 2011 J Pharm Sci pmid:21618542
Fenoll A et al. Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009. 2011 BMC Infect. Dis. pmid:21910891
Qin X et al. Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. 2011 Int. J. Antimicrob. Agents pmid:21549571
Maezono H et al. Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. 2011 Antimicrob. Agents Chemother. pmid:21911560
Sigaroudinia MO and Quayle AR Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. 2011 Surgeon pmid:21550524
Lehtopolku M et al. Ribosomal mutations as the main cause of macrolide resistance in Campylobacter jejuni and Campylobacter coli. 2011 Antimicrob. Agents Chemother. pmid:21911571
Drago L et al. Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. 2011 J. Microbiol. pmid:21887650
Liu K et al. Direct entry to erythronolides via a cyclic bis[allene]. 2011 J. Am. Chem. Soc. pmid:21894913
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Imperi M et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. 2011 Clin. Microbiol. Infect. pmid:21722258
Wan G et al. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. 2011 Cell. Signal. pmid:21723942
Miyashita N et al. Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. 2011 J. Infect. Chemother. pmid:20676912
You L et al. Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing. 2011 Nat Chem pmid:22109274
Braga TM et al. Involvement, and dissemination, of the enterococcal small multidrug resistance transporter QacZ in resistance to quaternary ammonium compounds. 2011 J. Antimicrob. Chemother. pmid:21147826
Allen VG et al. Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. 2011 Antimicrob. Agents Chemother. pmid:21098249
Miller E et al. Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. 2011 Lancet Infect Dis pmid:21621466
Song W et al. A novel strontium-doped calcium polyphosphate/erythromycin/poly(vinyl alcohol) composite for bone tissue engineering. 2011 J Biomed Mater Res A pmid:21626667
Wingard JB et al. A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. 2011 Antimicrob. Agents Chemother. pmid:21628536
Amachawadi RG et al. Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. 2011 Appl. Environ. Microbiol. pmid:21705534
Tanamachi C et al. [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. 2011 Rinsho Byori pmid:21706860
Mikura S et al. Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. 2011 Transl Res pmid:21708354
Richter SS et al. Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. 2011 Antimicrob. Agents Chemother. pmid:21709080
Muruganathan G et al. Interaction study of moxifloxacin and lomefloxacin with co-administered drugs. 2011 Pak J Pharm Sci pmid:21715267
Guo L et al. Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. 2011 Toxicol. Sci. pmid:21693436
Modali SD and Zgurskaya HI The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. 2011 Mol. Microbiol. pmid:21696464
Jorgensen JH et al. Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. 2011 J. Clin. Microbiol. pmid:21697321
Wenzel F et al. Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). 2011 Clin. Hemorheol. Microcirc. pmid:22214710
Amarir-Bouhram J et al. Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. 2011 PLoS ONE pmid:22194937
Panigaj M et al. Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. 2011 PLoS ONE pmid:21912705
Buendia J et al. Preparation of diastereomerically pure dilignol model compounds. 2011 Chemistry pmid:22076640
Maragno AL et al. ISG15 modulates development of the erythroid lineage. 2011 PLoS ONE pmid:22022510
Kreft A et al. JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. 2011 Virchows Arch. pmid:22006129
Zaed AM and Sutherland A Total synthesis of clavaminol A, C and H. 2011 Org. Biomol. Chem. pmid:21879135
Taillon MP et al. Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. 2011 Bioanalysis pmid:21877892
Koulnis M et al. Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response. 2011 PLoS ONE pmid:21760888
Louvet JN et al. Simultaneous Gram and viability staining on activated sludge exposed to erythromycin: 3D CLSM time-lapse imaging of bacterial disintegration. 2011 Int J Hyg Environ Health pmid:21420358
Serdoz F et al. Development and pharmacokinetic evaluation of erythromycin lipidic formulations for oral administration in rainbow trout (Oncorhynchus mykiss). 2011 Eur J Pharm Biopharm pmid:21402156
Marjanović N et al. Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro. 2011 Pharmacol. Res. pmid:21315154
Siibak T et al. Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. 2011 Mol. Microbiol. pmid:21320180
Veiga-Crespo P et al. Synergism between outer membrane proteins and antimicrobials. 2011 Antimicrob. Agents Chemother. pmid:21321143
Kataoka M et al. Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. 2011 Eur J Pharm Sci pmid:21963456
Hernández y Ballinas A et al. [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. 2011 Ginecol Obstet Mex pmid:21966834
Gupta R et al. A 14-year-old with rectal bleeding and abdominal pain. 2011 J. Pediatr. Gastroenterol. Nutr. pmid:21970991
Pignatello R et al. Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. 2011 AAPS PharmSciTech pmid:21479751
Keelan JA et al. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. 2011 Am. J. Obstet. Gynecol. pmid:21481833
Heath AP et al. An algorithm for efficient identification of branched metabolic pathways. 2011 J. Comput. Biol. pmid:21999288
Fan C and He J Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. 2011 Water Res. pmid:21482429
Ho PL et al. Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. 2011 Diagn. Microbiol. Infect. Dis. pmid:22000087
Franke RM et al. Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. 2011 Clin. Pharmacol. Ther. pmid:21451505
Gozalbes R et al. QSAR-based permeability model for drug-like compounds. 2011 Bioorg. Med. Chem. pmid:21458999
Boleda MA et al. Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. 2011 Environ. Pollut. pmid:21459501
Wu JC and Sung JJ Pharmacologic therapy for nonvariceal upper gastrointestinal bleeding. 2011 Gastrointest. Endosc. Clin. N. Am. pmid:21944417
Kovacs TO and Jensen DM Endoscopic therapy for severe ulcer bleeding. 2011 Gastrointest. Endosc. Clin. N. Am. pmid:21944418
Ozkok IP et al. Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. 2011 J Environ Sci Health A Tox Hazard Subst Environ Eng pmid:22029701
Justa RF et al. Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. 2011 Rev. Soc. Bras. Med. Trop. pmid:22031085
Flaman AS et al. The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. 2011 Toxicol. Appl. Pharmacol. pmid:21466820
Zou LK et al. Erythromycin resistance and virulence genes in Enterococcus faecalis from swine in China. 2011 New Microbiol. pmid:21344149
Liu L et al. Disappearance of sexual dimorphism in triptolide metabolism in monosodium glutamate treated neonatal rats. 2011 Arzneimittelforschung pmid:21428244
Lee Y et al. Chemistry and biology of macrolide antiparasitic agents. 2011 J. Med. Chem. pmid:21428405
Chen HX et al. [Compound erythromycin sustained release preparation and its in vitro release]. 2011 Yao Xue Xue Bao pmid:22260035
Wei Z et al. [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. 2011 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22260078
Li Y et al. Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. 2011 J. Appl. Microbiol. pmid:20961364
Vuppalanchi R et al. Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. 2011 J. Clin. Gastroenterol. pmid:20962670
Bansal BK et al. Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. 2011 Trop Anim Health Prod pmid:20844949