erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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GRIFFITH RS | The ratio of antimicrobial activity between propionyl erythromycin lauryl sulfate and erythromycin ethyl carbonate. | 1961 | Antibiot Chemother (Northfield) | pmid:13901862 |
GROGAN JB et al. | Antibiotic susceptibility of phage type 80/81 strains of staphylococci isolated from hospital and community populations. | 1962 | Antibiot Chemother (Northfield) | pmid:13902091 |
HASBROUCK RB and GARVEN FC | The chemistry of erythromycin. II. Acid degradation products. | 1953 | Antibiot Chemother (Northfield) | pmid:24542706 |
ANDERSON EA | Cure of resistant meningococcemia with erythromycin. | 1953 | Antibiot Chemother (Northfield) | pmid:24542853 |
HAIGHT TH et al. | Erythromycin therapy of respiratory infections. II. Effects of varying durations of therapy of streptococcal infections on eradication of streptococci and on formation of antistreptolysin O. | 1954 | Antibiot Chemother (Northfield) | pmid:24543018 |
LAING CR and SCOTT RB | Erythromycin-polymyxin ointment in the treatment of pyoderma in children. | 1954 | Antibiot Chemother (Northfield) | pmid:24543095 |
TUNEVALL G and HEDENIUS P | Laboratory and clinical studies with erythromycin. | 1954 | Antibiot Chemother (Northfield) | pmid:24543103 |
Ukhabotina LS et al. | [Cloning of clusters of erythromycin biosynthesis genes of Streptomyces erythraeus (Saccharopolyspora erythraea)]. | 1990 | Antibiot. Khimioter. | pmid:2150305 |
Zavorotnaia SA et al. | [Genetic instability of the feature of streptomycin resistance in Streptomyces erythraeus]. | 1990 | Antibiot. Khimioter. | pmid:2078071 |
Navashin SM and Nikitin AV | [New macrolide antibiotics, rifamycins and peptide antibiotics discussed at the 27th International Conference on Antimicrobial Agents and Chemotherapy]. | 1991 | Antibiot. Khimioter. | pmid:1850977 |
Motina GL et al. | [Effect of the methods of sterilization on the quality of nutrient media and on the level of antibiotic production]. | 1991 | Antibiot. Khimioter. | pmid:1814272 |
Arzumanian OG et al. | [Effect of partial pressure of solute oxygen on the intensity of respiration of cultures of antibiotic producers]. | 1990 | Antibiot. Khimioter. | pmid:2334239 |
Zakharova GM et al. | [Study of the effect of protoplast formation on the antibiotic activity of erythromycin producers]. | 1990 | Antibiot. Khimioter. | pmid:2334241 |
Korenev SV et al. | [Pharmacological availability of erythromycin granules for children's use]. | 1990 | Antibiot. Khimioter. | pmid:2264745 |
Dolgova GV et al. | [Experimental study of a novel formulation for local application based on gentamicin, erythromycin and protease C]. | 1990 | Antibiot. Khimioter. | pmid:2275587 |
Nigmatulin AZ et al. | [Antibiotic binding by leukocytes from brucellosis patients]. | 1990 | Antibiot. Khimioter. | pmid:2275592 |
Gagaeva EV and Firsov AA | [Pharmacokinetics of protegentin, a combined preparation]. | 1991 | Antibiot. Khimioter. | pmid:1953168 |
Nazarov AD et al. | [Erythromycin pharmacokinetics in children after rectal and oral administration]. | 1991 | Antibiot. Khimioter. | pmid:2025118 |
Berezhinskaia VV and Dolgova GV | [Macrolide antibiotics and their use in combined pharmacotherapy]. | 1989 | Antibiot. Khimioter. | pmid:2686571 |
Sytnik SI | [Antibiotic sensitivity of Staphylococci populating the breast skin of nursing women]. | 1989 | Antibiot. Khimioter. | pmid:2730223 |
Ukhabotina LS et al. | [Identification and characteristics of plasmids of the strains of erythromycin-producing Streptomyces erythreus]. | 1988 | Antibiot. Khimioter. | pmid:2837155 |
Bryzgalova TE et al. | [Conditions for immobilizing Streptomyces erythreus in a calcium alginate gel and the apparatus setup for the process]. | 1988 | Antibiot. Khimioter. | pmid:3288145 |
Oriabinskaia LB et al. | [Energy metabolism in Staphylococci containing plasmids of resistance to a number of antibiotics]. | 1992 | Antibiot. Khimioter. | pmid:1296533 |
Grigor'ev AE et al. | [Construction of hybrid plasmids containing genes for erythromycin biosynthesis and amplifying sequence AUD-Sr1 of Streptomyces rimosus]. | 1992 | Antibiot. Khimioter. | pmid:1296539 |
BureÄko SF et al. | [Various properties of erythromycin basicity]. | 1992 | Antibiot. Khimioter. | pmid:1514846 |
Petrova MS et al. | [Antibiotic therapy in children with pertussis]. | 1992 | Antibiot. Khimioter. | pmid:1300936 |
Sereda EV et al. | [Use of oral macrolide and azalide antibiotics in children with bronchopulmonary diseases]. | 1994 | Antibiot. Khimioter. | pmid:7840711 |
Fomina IP | [Second international conference on macrolides, azalides and streptogramins (Venice, Italy, January 19-22, 1994)]. | 1994 | Antibiot. Khimioter. | pmid:7914722 |
StrachunskiÄ LS et al. | [Comparative clinical effectiveness and tolerance of azithromycin (sumamed) and erythromycin in patients with sinusitis]. | 1993 | Antibiot. Khimioter. | pmid:8060176 |
Shubin SV et al. | [Effectiveness of azithromycin relative to chlamydia infection in reactive arthritis]. | 1993 | Antibiot. Khimioter. | pmid:8060177 |
Kirichenko NV et al. | [Isolation and characterization of genetic recombinants in protoplast fusion in Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8060179 |
Sazykin IuO | [Modern macrolides and azalides in the therapy of infectious-inflammatory diseases. A seminar, February 1994, Moscow]. | 1994 Feb-Mar | Antibiot. Khimioter. | pmid:7979801 |
Vasilos LV et al. | [Chemotherapeutic effectiveness of erythromycin, rifampicin and tetracyclines in chlamydiosis and mycoplasmosis in children]. | 1995 | Antibiot. Khimioter. | pmid:8593094 |
Belousov IuB et al. | [Dirithromycin in the treatment of infections of the lower respiratory tract]. | 1995 | Antibiot. Khimioter. | pmid:8645058 |
Zurabyan VA et al. | [In vitro influence of biologically active factors of microorganisms on antibiotic susceptibility of Yersinia pestis]. | 1997 | Antibiot. Khimioter. | pmid:9463297 |
Sadovnikova SF and Selina EV | [Five years of sumamed on Russian market]. | 1997 | Antibiot. Khimioter. | pmid:9463300 |
Fomina IP et al. | [Azithromycin (sumamed)--in the treatment of respiratory tract infections]. | 1996 | Antibiot. Khimioter. | pmid:8929121 |
Kurmanova KB et al. | [Efficacy of pefloxacin in the treatment of complicated relapsing erysipelas]. | 1997 | Antibiot. Khimioter. | pmid:9480650 |
MashkilleÄson AL | [Azithromycin in the treatment of syphilis]. | 1994 | Antibiot. Khimioter. | pmid:7848005 |
Pozdniakova VP et al. | [Protegentin--a combined preparation for the local treatment of suppurative infection]. | 1993 Oct-Nov | Antibiot. Khimioter. | pmid:8085892 |
Bulgakova VG et al. | [Metabolism of alpha-ketoacids in erythromycin biosynthesis in various strains of Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8166559 |
Kirichenko VN et al. | [Use of protoplast fusion in the selection of erythromycin-producing strains of Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8166562 |
Kolpakov AI et al. | [Use of exogenous ribonuclease for improvement of Lactobacillus biological properties]. | 1998 | Antibiot. Khimioter. | pmid:9791680 |
Platonova MM et al. | [Clinical significance of fungal and microbial associations and antibacterial therapy for treatment of chronic inflammatory respiratory tract diseases in children]. | 1998 | Antibiot. Khimioter. | pmid:9791682 |
Sazykin IuO et al. | [Ketolides--erythromycin derivatives with activity against macrolide-resistant bacteria]. | 2000 | Antibiot. Khimioter. | pmid:10707799 |
Strachynskił LS et al. | [Pharmacoepidemiology of antibiotics in the treatment of respiratory tract infections in pediatric outpatients]. | 1997 | Antibiot. Khimioter. | pmid:9412396 |
Nastasyak IN | [Localization of rifampicin resistance determinants on genetic map of Saccharopolyspora erythraea]. | 1997 | Antibiot. Khimioter. | pmid:9412406 |
Michurina TA et al. | [Antioxidant effect on the growth of Saccharopolyspora erythraea and biosynthesis of erythromycins]. | 2005 | Antibiot. Khimioter. | pmid:19140479 |
Kotova NV | [Kinetic and equilibrium parameters of erythromycin sorption on various sorbents]. | 2009 | Antibiot. Khimioter. | pmid:20583559 |
Grudinina SA et al. | [Dynamics of Streptococcos pneumoniae antibiotic resistance extension in Moscow in 1998-2003]. | 2004 | Antibiot. Khimioter. | pmid:15460020 |
Guchev IA et al. | [Efficacy and safety of azithromycin prophylaxis of respiratory tract infections in military community]. | 2004 | Antibiot. Khimioter. | pmid:15727144 |
Minaeva NZ et al. | [Bacteria of the genus Arcobacter, a new etiological factor of nosocomial infections]. | 2006 | Antibiot. Khimioter. | pmid:16878388 |
Gurevich KG et al. | [Comparative pharmacokinetics of erythromycin target cell-associated transport and intravenous administration in patients with pneumonia]. | 2006 | Antibiot. Khimioter. | pmid:18030786 |
Lialikov SA et al. | [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. | 2012 | Antibiot. Khimioter. | pmid:23700934 |
Efimova OG et al. | [Electron microscopic study of the interaction of cultures of Bordetella pertussis altered by antibiotic action with a human amniotic cell culture]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:2878640 |
Bukharovich AM and Kuz'menko VA | [Effectiveness of complex therapy using ericyclin in patients with chronic pyoderma (5-year catamnestic data)]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:3767332 |
Gusakova GV et al. | [IR spectral research on erythromycin mono- and dihydrates]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:3777893 |
Gusakova GV et al. | [Infrared spectra and the molecular conformations of macrolide-group antibiotics in solution]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:3777894 |
Listvinova SN et al. | [Dynamics of protein biosynthesis in a Streptomyces erythreus culture and its alteration as affected by exogenous erythromycin]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:3717921 |
Lapchinskaia AV et al. | [Changes in the microflora of the large intestine in rats administered cephalexin and erythromycin orally]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:3579249 |
Gorskaia EM et al. | [The adhesive capacity of representative intestinal microflora in the continuous and split oral administration of cephalexin and erythromycin]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:3555328 |
Katrush VR and Zhukovskaia SA | [Separation of emulsions during extraction of antibiotics from native solutions]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:3606053 |
Tsirkin RS | [Antibiotic sensitivity of staphylococci associated with adenoviruses]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:3923916 |
Kuznetsov LE | [Effect of a temperature regimen on erythromycin biosynthesis]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:4051468 |
Kivman GIa et al. | [Binding by subcellular fractions of rat liver homogenate and intracellular distribution of antibiotics in acute radiation injury]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:4062269 |
Guliaev AE and Kivman GIa | [Macrolide antibiotics: characteristics of their interaction with organoids, intracellular distribution and the effect of sulfalene]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:4004182 |
STRYKER H et al. | The allergenicity of erythromycin. | 1958 | Antibiotic Med Clin Ther (New York) | pmid:13606766 |
MITSUI Y et al. | Treatment of trachoma with erythromycin-sulfacetamide ointment (CT-877). | 1958 | Antibiotic Med Clin Ther (New York) | pmid:13583947 |
GRIFFITH RS et al. | Preliminary studies on propionyl erythromycin. | 1958 | Antibiotic Med Clin Ther (New York) | pmid:13583951 |
DE FRANCO VJ | The efficacy of erythromycin in the control and prevention of an endemic staphylococcal infection in a large private hospital nursery. | 1958 | Antibiotic Med Clin Ther (New York) | pmid:13571962 |
PEELE JC | Erythromycin (ilotycin); minimal dosage therapy in the treatment of acute infections of the upper respiratory tract and external auditory canal. | 1957 | Antibiotic Med Clin Ther (New York) | pmid:13403626 |
WOOD N and O'GORMAN G | Erythromycin treatment of a diphtheria carrier epidemic in a mental deficiency hospital. | 1957 | Antibiotic Med Clin Ther (New York) | pmid:13445087 |
EDELSTEIN AJ | Treatment of infected acne with erythromycin. | 1958 | Antibiotic Med Clin Ther (New York) | pmid:13509625 |
TRAFTON HM and LIND HE | Oleandomycin in urinary tract infections. | 1957 | Antibiotic Med Clin Ther (New York) | pmid:13488411 |
HERRELL WE et al. | Erythrocillin: a new approach to the problem of antibiotic-resistant staphylococci. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13713711 |
CLAPPER WE et al. | An evaluation of erythromycin stearate and propionyl erythromycin in normal and hospitalized subjects. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13810414 |
CRONK GA and NAUMANN DE | The treatment of infections with erythromycin propionate. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13812968 |
DELTA BG and SCOTT RB | Erythromycin propionate ointment in the treatment of cutaneous bacterial infections in children. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13815757 |
BEEZY R et al. | Use of erythromycin propionate in hospital infections. | 1961 | Antibiotic Med Clin Ther (New York) | pmid:13688651 |
LIMSON BM and ARAGON PR | Clinical and in vitro efficacy of propionyl erythromycin ester. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13762200 |
GRIFFITH RS | Comparison of antibacterial activity in the sera of subjects ingesting propionyl erythromycin lauryl sulfate and erythromycin ethyl carbonate. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13851768 |
PERRY DM et al. | Triacetyloleandomycin and erythromycin: a comparison of in vitro activity and of blood levels obtained after oral administration. | 1959 | Antibiotic Med Clin Ther (New York) | pmid:13661850 |
TIDWELL RA and LEWIS D | Erythromycin prophylaxis: a four year study. | 1959 | Antibiotic Med Clin Ther (New York) | pmid:13661855 |
QUINN EL et al. | Comparative studies of erythromycin propionate, erythromycin stearate, and triacetyloleandomycin. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14435562 |
SETTEL E | Evaluation of erythromycin propionate (ilosone) in general practice. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14445202 |
SHUBIN H et al. | Clinical studies of propionyl erythromycin in infections. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14446275 |
HALL GA et al. | Erythromycin stearate and propionyl erythromycin: a comparison of blood levels obtained after oral administration. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14399035 |
ISENBERG HD et al. | A clinical and laboratory evaluation of propionyl erythromycin. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14405887 |
BRANNICK TL et al. | Comparison of levels of carbomycin A, carbomycin B, and erythromycin in serum and thyroid tissue. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:14362447 |
WILLCOX RR | Erythromycin in nongonococcal urethritis. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:14362449 |
TAKIMURA Y et al. | Intrapleural administration of erythromycin. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:14362457 |
SHAFEI AZ | Erythromycin as an amebicide; a preliminary report. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:14362464 |
BREM J and KABILING TR | Clinical evaluation of erythromycin in pertussis. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:14362467 |
SHAFEI AZ | A comparative study of the use of combinations of fumagillin and tetracycline or erthromycin in the treatment of intestinal amebiasis; a preliminary report. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:13259476 |
HERRELL WE et al. | Erythromycin in the treatment of actinomycosis. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:13259478 |
URTEAGA OB et al. | Erythromycin in human brucellosis. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:13259479 |
TAKIMURA Y and LOPEZ-BELIO M | Excretion of erythromycin through the biliary tract. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:13259483 |
MARMELL M and PRIGOT A | An erythromycin triple sulfonamide combination in the treatment of early lymphogranuloma venereum. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:13239093 |
MARMELL M et al. | Erythromycin in combination with triple sulfonamides in the treatment of acute gonorrhea in the male. | 1955 | Antibiotic Med Clin Ther (New York) | pmid:13239100 |
Serra P et al. | [Antibiotic combinations synergic for enterococci]. | 1972 Jan-Jun | Antibiotica | pmid:4679551 |