erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Palmieri C et al. | Interspecies mobilization of an ermT-carrying plasmid of Streptococcus dysgalactiae subsp. equisimilis by a coresident ICE of the ICESa2603 family. | 2013 | J. Antimicrob. Chemother. | pmid:22949621 |
Nemeghaire S et al. | Characterization of methicillin-resistant Staphylococcus aureus from healthy carrier chickens. | 2013 | Avian Pathol. | pmid:23777220 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Wasels F et al. | Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. | 2013 | J. Med. Microbiol. | pmid:23741023 |
Kawai Y et al. | Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. | 2013 | Antimicrob. Agents Chemother. | pmid:23716043 |
González-Hein G et al. | [Molecular analysis of fluoroquinolones and macrolides resistance in Campylobacter jejuni isolates from humans, bovine and chicken meat]. | 2013 | Rev Chilena Infectol | pmid:23677151 |
Derrouiche S et al. | Process design for wastewater treatment: catalytic ozonation of organic pollutants. | 2013 | Water Sci. Technol. | pmid:24056437 |
Jiang M et al. | Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. | 2013 | Metab. Eng. | pmid:24060454 |
Gold RM and Lawhon SD | Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. | 2013 | J. Clin. Microbiol. | pmid:24025915 |
Avci O et al. | A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. | 2013 | J Dermatolog Treat | pmid:21923567 |
Pohl O et al. | Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. | 2013 | J Clin Pharm Ther | pmid:24102384 |
Panditi VR et al. | Online solid-phase extraction-liquid chromatography-electrospray-tandem mass spectrometry determination of multiple classes of antibiotics in environmental and treated waters. | 2013 | Anal Bioanal Chem | pmid:23494277 |
Kwak HM et al. | The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. | 2013 | Placenta | pmid:23465535 |
Desroy N et al. | Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence. | 2013 | J. Med. Chem. | pmid:23409840 |
Magee TV et al. | Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23414806 |
Lermite E et al. | Complications after pancreatic resection: diagnosis, prevention and management. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23415988 |
Atamanyuk D et al. | Vectorization efforts to increase Gram-negative intracellular drug concentration: a case study on HldE-K inhibitors. | 2013 | J. Med. Chem. | pmid:23445125 |
Gomes DL et al. | SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. | 2013 | J. Med. Microbiol. | pmid:23449875 |
Liu JF et al. | [Effect of erythromycin on electrical activity and gastric emptying of the intrathoracic stomach after esophagectomy for esophageal cancer]. | 2013 | Zhonghua Wei Chang Wai Ke Za Zhi | pmid:24061999 |
Hahn A et al. | The outer membrane TolC-like channel HgdD is part of tripartite resistance-nodulation-cell division (RND) efflux systems conferring multiple-drug resistance in the Cyanobacterium Anabaena sp. PCC7120. | 2013 | J. Biol. Chem. | pmid:24014018 |
Capanna F et al. | Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. | 2013 | Swiss Med Wkly | pmid:23572445 |
Mu X et al. | Effects of erythromycin and rifampicin on immunomodulatory gene expression and cellular function in human polymorphonuclear leukocytes. | 2013 | Chemotherapy | pmid:24852442 |
Ferrieri P et al. | Serotype IV and invasive group B Streptococcus disease in neonates, Minnesota, USA, 2000-2010. | 2013 | Emerging Infect. Dis. | pmid:23628320 |
Chang YC and Lo HH | Identification, clinical aspects, susceptibility pattern, and molecular epidemiology of beta-haemolytic group G Streptococcus anginosus group isolates from central Taiwan. | 2013 | Diagn. Microbiol. Infect. Dis. | pmid:23632249 |
Müller M et al. | The absolute configuration of (+)- and (-)-erythro-mefloquine. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23616269 |
Gaudreau C et al. | Campylobacter coli outbreak in men who have sex with men, Quebec, Canada, 2010-2011. | 2013 | Emerging Infect. Dis. | pmid:23647786 |
Kjær S et al. | Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. | 2013 | Dan Med J | pmid:23651712 |
Ragazzi E et al. | Saliva concentration of amoxicillin, erythromycin, and ciprofloxacin in outpatients: a comparison between the young and the elderly. | 2013 | J Chemother | pmid:23684362 |
Rasamiravaka T et al. | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients. | 2013 | J Infect Dev Ctries | pmid:23592641 |
Simoens S et al. | Preventing COPD exacerbations with macrolides: a review and budget impact analysis. | 2013 | Respir Med | pmid:23352223 |
Jiang M et al. | The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. | 2013 | J Vis Exp | pmid:23354010 |
Elens L et al. | CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. | 2013 | Pharmacogenomics | pmid:23327575 |
Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
Cui B et al. | Differences between two clinical Staphylococcus capitis subspecies as revealed by biofilm, antibiotic resistance, and pulsed-field gel electrophoresis profiling. | 2013 | J. Clin. Microbiol. | pmid:23052315 |
Baltar F et al. | Bacterial versus archaeal origin of extracellular enzymatic activity in the Northeast Atlantic deep waters. | 2013 | Microb. Ecol. | pmid:23015014 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
Ishibashi K et al. | Short-term intravenous antimicrobial prophylaxis for elective rectal cancer surgery: results of a prospective randomized non-inferiority trial. | 2014 | Surg. Today | pmid:23989910 |
Wang J et al. | Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. | 2014 | Hum. Immunol. | pmid:24120738 |
Cetecioglu Z | Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24146324 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Haworth CS et al. | Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. | 2014 | Respir Med | pmid:25301290 |
Nikolay R et al. | Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. | 2014 | Nucleic Acids Res. | pmid:24792169 |
Barbosa TM et al. | A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. | 2014 | PLoS ONE | pmid:25548909 |
Liao D et al. | Quantitative differences between primary and secondary peristaltic contractions of the esophagus. | 2014 | Dig. Dis. Sci. | pmid:24682721 |
Hudson BH and Zaher HS | Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. | 2014 | Mol. Cell | pmid:25514181 |
Källén B and Danielsson BR | Fetal safety of erythromycin. An update of Swedish data. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24352632 |
Rozov-Ung I et al. | Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. | 2014 | BMC Gastroenterol | pmid:24383478 |
Miyazaki M et al. | [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. | 2014 | Yakugaku Zasshi | pmid:24492229 |
Arenz S et al. | Drug sensing by the ribosome induces translational arrest via active site perturbation. | 2014 | Mol. Cell | pmid:25306253 |
Belén Flórez A et al. | Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. | 2014 | Biomed Res Int | pmid:25302306 |
Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
Farabella I et al. | Allosteric signalling in the outer membrane translocation domain of PapC usher. | 2014 | Elife | pmid:25271373 |
Jaiswal N et al. | Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. | 2014 | PLoS ONE | pmid:25268974 |
Katayama Y et al. | Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. | 2014 | Brain Res. | pmid:25264351 |
Bauer CA and Grimme S | First principles calculation of electron ionization mass spectra for selected organic drug molecules. | 2014 | Org. Biomol. Chem. | pmid:25260171 |
Abarzúa F et al. | [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at ClÃnica Alemana Temuco, Southern Chile]. | 2014 | Rev Chilena Infectol | pmid:25146205 |
Carls A et al. | Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. | 2014 | Br J Clin Pharmacol | pmid:25139487 |
Compain F et al. | Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. | 2014 | Antimicrob. Agents Chemother. | pmid:25136004 |
Wagner G et al. | [Childhood granulomatous periorificial dermatitis]. | 2014 | Hautarzt | pmid:25115983 |
Shen Y et al. | Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. | 2014 | ScientificWorldJournal | pmid:25110723 |
Tagawa J et al. | Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. | 2014 | J. Microbiol. Methods | pmid:25102110 |
Serna-Tamayo C et al. | Neonatal and infantile acne vulgaris: an update. | 2014 | Cutis | pmid:25101339 |
Kinouchi H et al. | Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. | 2014 | Biol. Pharm. Bull. | pmid:25087959 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Mott M et al. | Susceptibility profiles and correlation with pneumococcal serotypes soon after implementation of the 10-valent pneumococcal conjugate vaccine in Brazil. | 2014 | Int. J. Infect. Dis. | pmid:24389158 |
Mayanskiy N et al. | Serotypes and antibiotic resistance of non-invasive Streptococcus pneumoniae circulating in pediatric hospitals in Moscow, Russia. | 2014 | Int. J. Infect. Dis. | pmid:24462930 |
Dutra VG et al. | Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility. | 2014 | BMC Infect. Dis. | pmid:24919844 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Borbón-Esquer EM et al. | SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. | 2014 | Scand. J. Infect. Dis. | pmid:24832853 |
Wang Z et al. | High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. | 2014 | Clin. Microbiol. Infect. | pmid:24816168 |
Allen LN | Mild meningococcaemia, pyrexia protocols and a problematic public health response. | 2014 | BMJ Case Rep | pmid:24811106 |
Mulatu G et al. | Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. | 2014 | Ethiop J Health Sci | pmid:24795510 |
Wu P et al. | SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea. | 2014 | J. Ind. Microbiol. Biotechnol. | pmid:24793123 |
de las Heras MN | Linear IgA bullous dermatosis of childhood: good response to antibiotic treatment. | 2014 | Clin. Exp. Dermatol. | pmid:24772486 |
Kawaguchiya M et al. | Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. | 2014 | Microb. Drug Resist. | pmid:24766085 |
Gaudreau C et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli isolates obtained in Montreal, Quebec, Canada, from 2002 to 2013. | 2014 | J. Clin. Microbiol. | pmid:24759726 |
Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
Murphree CA et al. | Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. | 2014 | Curr. Microbiol. | pmid:24748439 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Jun BY et al. | Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. | 2014 | Surg Endosc | pmid:24380989 |
Ren WP et al. | Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. | 2014 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:24347324 |
Brenciani A et al. | Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. | 2014 | J. Antimicrob. Chemother. | pmid:24343896 |
Lu WC et al. | Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. | 2014 | Neurol. Sci. | pmid:24277204 |
Thumu SC and Halami PM | Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. | 2014 | J. Appl. Microbiol. | pmid:24206069 |
Lu B et al. | Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. | 2014 | Clin. Microbiol. Infect. | pmid:24118553 |
Zheng PX et al. | Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. | 2014 | Clin. Microbiol. Infect. | pmid:24118239 |
Singh P et al. | Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. | 2014 | Fundam Clin Pharmacol | pmid:24117516 |
Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. | 2014 | J. Fish Dis. | pmid:23992037 |