erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Lacrimal Duct Obstruction D007767 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Sporotrichosis D013174 3 associated lipids
Ehrlichiosis D016873 2 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Rubella D012409 2 associated lipids
Pleural Diseases D010995 4 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Erythema Multiforme D004892 3 associated lipids
Prolapse D011391 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
Heart Murmurs D006337 1 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Bartonella Infections D001474 3 associated lipids
Scarlet Fever D012541 1 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Dry Socket D004368 3 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Sialadenitis D012793 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Megacolon D008531 1 associated lipids
Relapsing Fever D012061 3 associated lipids
Carbuncle D002270 1 associated lipids
Furunculosis D005667 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Marfan Syndrome D008382 2 associated lipids
Elephantiasis D004604 2 associated lipids
Lymphangitis D008205 4 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Griaznova NS et al. [Cooperative functioning of 2 systems of protection against its own antibiotic in Str. erythreus 1571, a superproducer of erythromycin]. 1982 Antibiotiki pmid:7065644
Bukharovich AM [Microbiological substantiation of the use of erycycline in the therapy of chronic pyoderma]. 1982 Antibiotiki pmid:7092196
Zueva VS et al. [Transmission of extrachromosomal drug resistance in staphylococci present in animals and the effect of neomycin on this process]. 1970 Antibiotiki pmid:5489278
Grinenko GI and Smolianskaia AZ [Structure of multiple drug resistance in Staphylococcus. Combination of multiple drug resistance markers in staphylococci isolated from patients in an oncological clinic]. 1972 Antibiotiki pmid:4489635
Blinov NO and Khokhlov AS [Paper chromatography and electrophoresis in the study of the transformation of antibiotics in the human and animal body]. 1967 Antibiotiki pmid:4874768
Ankirskaia AS and Voropaeva SD [Experimental chronic infection caused by clinical, multiply resistant strains of Staphylococcus and their variants with eliminated resistance]. 1972 Antibiotiki pmid:4489636
Maichuk IuF [Antibiotics in polyvinyl alcohol film for treatment of infectious eye diseases]. 1967 Antibiotiki pmid:4874770
Levitov MM and Brinberg SL [Physiology of antibiotic-producing microorganisms and the process of biosynthesis of antibiotics]. 1967 Antibiotiki pmid:4875265
Garanin BA [Analysis of the sensitivity toward some antibiotics of Salmonellas isolated from patients during 1960-1966]. 1968 Antibiotiki pmid:4876633
Garanin BA [Sensitivity toward antibiotics of Shigella Sonnei of individual fermentative types based on data from a hospital for communicable diseases during 1966]. 1968 Antibiotiki pmid:4877060
Listvinova SN et al. [Action of erythromycin on its own producer in cultivation on broth media]. 1983 Antibiotiki pmid:6859818
Imshenetskaia VF [Correlation between levels of staphylococcal resistance to antibiotics and amounts used in clinical practice]. 1974 Antibiotiki pmid:4499631
Tumanian MA and Izvekova AV [Chemotherapy of experimental animals with radiation sickness and intestinal microflora resistant to several antibiotics]. 1974 Antibiotiki pmid:4499704
EÄ­del'shteÄ­n SI et al. [Erythromycin aerosols]. 1965 Antibiotiki pmid:5872439
Shestialtynova IS [Effect of tetracycline in combination with other antibiotics on causative agents of purulent infection]. 1971 Antibiotiki pmid:4995503
Shtol'ts MG et al. [Erythromycin polymorphism]. 1966 Antibiotiki pmid:5988109
Shorin VA and Shapovalova SP [The antibacterial and chemotherapeutic activity of the Soviet produced antibiotic rifamitsina SV]. 1974 Antibiotiki pmid:4156904
Belizhenko GG [Effect of trypsin on the activity of tetracycline, erythromycin and levomycetin]. 1975 Antibiotiki pmid:1180534
Liashenko IuI [Effect of penicillin and erythromycin on immunity in angina]. 1982 Antibiotiki pmid:6980620
Mel'nikova VM et al. [Experience in the use of lincomycin in the treatment of staphylococcal infections in traumatologic and orthopedic patients]. 1969 Antibiotiki pmid:5196670
VAKULENKO NA [Determination of erythromycin in serum and urine by the agar diffusion method]. 1961 Antibiotiki pmid:13779655
Givental' NI et al. [Tolerance of group A streptococci to the bactericidal effect of various antibiotics]. 1984 Antibiotiki pmid:6098218
Vakulenko NA [Unification of the method for determination of biological activity of antibiotics by means of single test culture]. 1968 Antibiotiki pmid:4976625
Klimov AN et al. [Comparative study of DNA of resistant and sensitive to antibiotic combination hemolytic streptococci]. 1969 Antibiotiki pmid:4976745
Dushkin VA et al. [How to obtain specific pathogen-free mice by the antibiotic decontamination method]. 1971 Antibiotiki pmid:4333291
SAVITSKAIA EP [A METHOD FOR THE DETERMINATION OF THE ANTIBIOTIC SENSITIVITY OF RICKETTSIA BURNETI IN VITRO]. 1963 Antibiotiki pmid:14078815
MOROZ AF [DIFFERENCES IN THE RESISTANCE OF BACTERIA TO ANTIBACTERIAL SUBSTANCES AND THEIR ROLE IN THE DEVELOPMENT OF DRUG-RESISTANT MICROORGANISMS]. 1964 Antibiotiki pmid:14223632
IMSHENETSKAIA VF [COMPARATIVE EVALUATION OF THE EFFECTIVNESS OF AN ERYTHROMYCIN BASE AND ERYTHROMYCIN ASCORBATE IN EXPERIMENTAL MENINGITIS]. 1963 Antibiotiki pmid:14078820
KISELEV VI [USE OF VARIOUS COMBINATIONS OF ANTIBIOTICS IN THE TREATMENT OF DIPHTHERIAL BACTERIAL CARRIAGE]. 1964 Antibiotiki pmid:14223637
VASILEVA NG [EFFECT OF ANTIBIOTIC THERAPY ON BILIARY MICROFLORA IN CHRONIC CHOLECYSTITIS PATIENTS]. 1964 Antibiotiki pmid:14223638
Tereshin IM [Mechanism of action of mitomycin C on genetic transformation of hemolytic Streptococci]. 1969 Antibiotiki pmid:4982962
Serebrennikova II [Correlation between sensitivity of diphtheria bacteria to antibiotics and the presence of fungi of the Candida order]. 1969 Antibiotiki pmid:4982964
Brikman DI and Zakhlebnaia OD [Sensitivity of various races of the tularemia microbe to erythromycin, oleandomycin and polymyxin]. 1976 Antibiotiki pmid:179462
Gauze GF [Current methods of determination of the sensitivity of bacteria to antibiotics and their significance for rational antibiotic therapy]. 1969 Antibiotiki pmid:4311307
Kostareva MG [Hygroscopic properties of different drug preparations of erythromycin]. 1971 Antibiotiki pmid:5567752
Iurenev PN et al. [Agglomeration reaction of leukocytes in diagnosis of allergic reactions to antibiotics]. 1972 Antibiotiki pmid:4664107
CHERNOMORDIK AB et al. [THE SENSITIVITY OF DIPHTHERIA BACTERIA TO THE MACROLIDE ANTIBIOTICS: ERYTHROMYCIN, OLEANDOMYCIN AND SEKAZIN]. 1964 Antibiotiki pmid:14186718
ONDRACHEK Z [ON THE EFFECTIVENESS OF CERTAIN ANTIBIOTICS IN THE TREATMENT OF INFECTIOUS BILIARY DISEASES]. 1964 Antibiotiki pmid:14186720
Kuzina ZA and Tereshin IM [Sedimentation properties of Salmonella pullorum ribosomes and the effect of antibiotics on them]. 1974 Antibiotiki pmid:4463881
Abkarovich GF [The relationship between the effectiveness of complex antibacterial therapy of acute pneumonia and calculation of the sensitivity of sputum microflora]. 1974 Antibiotiki pmid:4463888
Zabalueva TS et al. [Sensitivity to antibiotics of staphylococci, isolated in city of Gor'kiu]. 1968 Antibiotiki pmid:4237512
Baroian OV et al. [Distribution of carriers of resistant Staphylococcus strains among healthy persons and its connection with the use of antibiotics]. 1970 Antibiotiki pmid:4923139
MOROZ AF [STUDY ON THE COMBINED EFFECT OF MIXTURES OF TETRACYCLINE AND PREPARATIONS FROM THE MACROLID GROUP ON STAPHYLOCOCCI RESISTANT TO VARIOUS ANTIBIOTICS]. 1963 Antibiotiki pmid:14130402
PASHIN AV [STUDIES ON THE ANTIBIOTIC SENSITIVITY ENTEROPATHOGENIC INTESTINAL BACILLI AND ON ITS RELATION TO THE CARRIAGE OF SYMBIOTIC PHAGES]. 1964 Antibiotiki pmid:14242808
Proskurov VA [Antibiotic sensitivity and dependence between pathogenic properties of staphylococci and antibiotic resistance]. 1972 Antibiotiki pmid:4483686
Plakunov VK and Myl'nikova SI [2 mechanisms of tetracycline resistance in bacteria]. 1976 Antibiotiki pmid:793507
Chernomordik AB [Synergistic action of antibiotics on Bacillus pyocianaeus]. 1967 Antibiotiki pmid:4300088
Tereshin IM [Study of the mechanism of action of actinomycin C on genetic transformation of Streptococcus haemolyticus]. 1969 Antibiotiki pmid:4181312
Ermol'eva ZV et al. [Sensitivity of cholera vibrios to antibiotics]. 1969 Antibiotiki pmid:4182157
Veselov AIa and Plotnikova NI [Species composition of excreted Shigella and the characteristic of their sensitivity to antibiotics during 11 years (1959-1969)]. 1971 Antibiotiki pmid:4934035
Zadvorniak PV and BronshteÄ­n RE [Microflora of lungs in pneumonias of infants and its sensitivity to antibiotics]. 1969 Antibiotiki pmid:4391893
Sobolev VR et al. [Comparative study of the sensitivity to different antibiotics of Staphylococci isolated from patients and attendants]. 1971 Antibiotiki pmid:4934037
Veselov AIa [Structure of drug resistance in Staphylococci]. 1976 Antibiotiki pmid:799486
Kalabukhova NF [Effect of ampicillin and different combination of antibiotics in relation to Staphylococci isolated from patients with enterocolitis]. 1969 Antibiotiki pmid:4901555
Baroian OV et al. [Resistance of Shigella to antibiotics]. 1974 Antibiotiki pmid:4614699
Baskanchiladze GSh and Buniatova IM [Change in the sensitivity to antibiotics of pathogenic staphylococci, isolated in Tiflis during 1961-1966]. 1968 Antibiotiki pmid:4303353
IAKOBSON LM et al. [Attempted international standardization of erythromycin]. 1958 Mar-Apr Antibiotiki (Mosc) pmid:24544839
Calvert H et al. Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. 2014 Anticancer Drugs pmid:24637575
Ohkura K et al. Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. 2009 Anticancer Res. pmid:19414330
Kiso S et al. Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats. 2000 Sep-Oct Anticancer Res. pmid:11062690
Gunics G et al. Enhanced antibacterial effect of erythromycin in the presence of 3,5-dibenzoyl-1,4-dihydropyridines. 2001 Jan-Feb Anticancer Res. pmid:11299745
OSWALD EJ et al. IN VITRO ANTISTAPHYLOCOCCAL EFFECTS OF ERYTHROMYCIN COMBINED WITH SEMISYNTHETIC PENICILLINS. 1964 Antimicrob Agents Chemother (Bethesda) pmid:14287966
GUZE LB and KALMANSON GM EFFECT OF ERYTHROMYCIN ON IN VIVO "PROTOPLAST" INFECTION. 1964 Antimicrob Agents Chemother (Bethesda) pmid:14288026
Garrison DW et al. Comparison of in vitro antibacterial activities of 7-chloro-7-deoxylincomycin, lincomycin, and erythromycin. 1967 Antimicrob Agents Chemother (Bethesda) pmid:5596165
Duncan IB Development of lincomycin resistance by staphylococci. 1967 Antimicrob Agents Chemother (Bethesda) pmid:5596212
TAUBMAN SB et al. EFFECT OF ERYTHROMYCIN ON PROTEIN BIOSYNTHESIS IN BACILLUS SUBTILIS. 1963 Antimicrob Agents Chemother (Bethesda) pmid:14274930
SELL SH and SANDERS RS THERAPY WITH ERYTHROMYCIN ESTOLATE FOR OTITIS MEDIA ASSOCIATED WITH HAEMOPHILUS INFLUENZAE INFECTION. 1963 Antimicrob Agents Chemother (Bethesda) pmid:14274999
MOFFETT HL et al. ERYTHROMYCIN ESTOLATE AND PHENOXYMETHYL PENICILLIN IN THE TREATMENT OF STREPTOCOCCAL PHARYNGITIS. 1963 Antimicrob Agents Chemother (Bethesda) pmid:14275000
Spizek J et al. Biogenetic relationship of the erythromycins and the lactone of erythromycin B. 1965 Antimicrob Agents Chemother (Bethesda) pmid:5883418
Grady JE and Stern KF Penetration of lincomycin into bone. 1965 Antimicrob Agents Chemother (Bethesda) pmid:5883427
Rasch JR and Mogabgab WJ Therapeutic effect of erythromycin on Mycoplasma pneumoniae pneumonia. 1965 Antimicrob Agents Chemother (Bethesda) pmid:5883484
Whaley HA et al. LL-A0341 A and B, new antibiotics. I. Isolation and characterization. 1966 Antimicrob Agents Chemother (Bethesda) pmid:5985292
Wilhelm JM et al. Interaction of antibiotics with ribosomes: structure-function relationships and a possible common mechanism for the antibacterial action of the macrolides and lincomycin. 1967 Antimicrob Agents Chemother (Bethesda) pmid:4970204
Perun TJ et al. Conformation of mactolide antibiotics. IV. Nuclear magnetic resonance, circular dichroism, and chemical studies of erythromycin derivatives. 1969 Antimicrob Agents Chemother (Bethesda) pmid:5396476
Jones PH et al. Chemical modifications of erythromycin antibiotics. II. Synthesis of 4'-hydroxyerythromycin A. 1969 Antimicrob Agents Chemother (Bethesda) pmid:5396478
Zinner SH et al. Erythromycin plus alkalinization in treatment of urinary infections. 1969 Antimicrob Agents Chemother (Bethesda) pmid:5396518
Weinstein MJ et al. Preliminary studies on megalomicin, a new Micromonospora-produced macrolide antibiotic complex. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735370
Paterson PY and Madden GM Occurrence and erythromycin susceptibility of penicillin-resistant Viridans streptococci in rheumatic fever patients on oral penicillin prophylaxis. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735376
McGehee RF R et al. Resistance of Staphylococcus aureus to lincomycin, clinimycin, and erythromycin. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735385
Wick WE and Mallett GE New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. 1968 Antimicrob Agents Chemother (Bethesda) pmid:5735386
Kawamata J and Nakajima K Mode of action of colistin. 1965 Antimicrob Agents Chemother (Bethesda) pmid:5327517
Boyd RJ and Godzeski CW Selected antibiotic effects on the L-phase of Protus mirabilis in tissue culture. 1970 Antimicrob Agents Chemother (Bethesda) pmid:5521355
Vacher S et al. PCR-restriction fragment length polymorphism analysis for detection of point mutations associated with macrolide resistance in Campylobacter spp. 2003 Antimicrob. Agents Chemother. pmid:12604552
Occhialini A et al. Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes. 1997 Antimicrob. Agents Chemother. pmid:9420046
Pasculle AW et al. Antimicrobial therapy of experimental Legionella micdadei pneumonia in guinea pigs. 1985 Antimicrob. Agents Chemother. pmid:3878688
Hyder SL and Streitfeld MM Inducible and constitutive resistance to macrolide antibiotics and lincomycin in clinically isolated strains of Streptococcus pyogenes. 1973 Antimicrob. Agents Chemother. pmid:4586147
Pajukanta R et al. In vitro activity of azithromycin compared with that of erythromycin against Actinobacillus actinomycetemcomitans. 1992 Antimicrob. Agents Chemother. pmid:1329617
Roblin PM et al. Susceptibilities to clarithromycin and erythromycin of isolates of Chlamydia pneumoniae from children with pneumonia. 1994 Antimicrob. Agents Chemother. pmid:7979292
Pai SR et al. In vivo efficacy of the ketolide ABT-773 (cethromycin) against enterococci in a mouse peritonitis model. 2003 Antimicrob. Agents Chemother. pmid:12878548
Cochetti I et al. Molecular characterization of pneumococci with efflux-mediated erythromycin resistance and identification of a novel mef gene subclass, mef(I). 2005 Antimicrob. Agents Chemother. pmid:16304164
Villa P et al. Toxicity, uptake, and subcellular distribution in rat hepatocytes of roxithromycin, a new semisynthetic macrolide, and erythromycin base. 1988 Antimicrob. Agents Chemother. pmid:3190183
Champney WS and Tober CL Molecular investigation of the postantibiotic effects of clarithromycin and erythromycin on Staphylococcus aureus cells. 1999 Antimicrob. Agents Chemother. pmid:10348746
Ednie LM et al. Comparative antianaerobic activities of the ketolides HMR 3647 (RU 66647) and HMR 3004 (RU 64004). 1997 Antimicrob. Agents Chemother. pmid:9303406
Flamm RK et al. Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. 2014 Antimicrob. Agents Chemother. pmid:24514082
Mizukane R et al. Comparative in vitro exoenzyme-suppressing activities of azithromycin and other macrolide antibiotics against Pseudomonas aeruginosa. 1994 Antimicrob. Agents Chemother. pmid:8203850
Reinert RR et al. Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. 2008 Antimicrob. Agents Chemother. pmid:18378707
Mima T and Schweizer HP The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. 2010 Antimicrob. Agents Chemother. pmid:20498323
Shang S et al. In vitro effects of spectinomycin and ceftriaxone alone or in combination with other antibiotics against Chlamydia trachomatis. 2005 Antimicrob. Agents Chemother. pmid:15793145
Tarpay MM et al. In vitro activity of antibiotics commonly used in the treatment of otitis media against Streptococcus pneumoniae isolates with different susceptibilities to penicillin. 1982 Antimicrob. Agents Chemother. pmid:6922691
Czinn S et al. Susceptibility of Campylobacter pyloridis to three macrolide antibiotics (erythromycin, roxithromycin [RU 28965], and CP 62,993) and rifampin. 1986 Antimicrob. Agents Chemother. pmid:3767346