| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Prostatic Hyperplasia | D011470 | 20 associated lipids |
| Intraoperative Complications | D007431 | 5 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Eye Diseases | D005128 | 12 associated lipids |
| Salpingitis | D012488 | 2 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gunes N et al. | Erythromycin residue in honey from the Southern Marmara region of Turkey. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680838 |
| Wolter N et al. | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. | 2008 | Antimicrob. Agents Chemother. | pmid:18056269 |
| Zhu W et al. | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. | 2008 | Antimicrob. Agents Chemother. | pmid:18056272 |
| Onoma M et al. | Oral mitemcinal (GM-611), an erythromycin-derived prokinetic, accelerates normal and experimentally delayed gastric emptying in conscious dogs. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18047625 |
| Camilli R et al. | New genetic element carrying the erythromycin resistance determinant erm(TR) in Streptococcus pneumoniae. | 2008 | Antimicrob. Agents Chemother. | pmid:18070957 |
| He Z et al. | Suppression of oxidant-induced glutathione synthesis by erythromycin in human bronchial epithelial cells. | 2008 | Respiration | pmid:18032881 |
| Merino DÃaz L et al. | Prevalence and mechanisms of erythromycin and clindamycin resistance in clinical isolates of beta-haemolytic streptococci of Lancefield groups A, B, C and G in Seville, Spain. | 2008 | Clin. Microbiol. Infect. | pmid:18034859 |
| Ikeda H et al. | EM703, the new derivative of erythromycin, inhibits transcription of type I collagen in normal and scleroderma fibroblasts. | 2008 | J. Dermatol. Sci. | pmid:18036782 |
| Feder M et al. | Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics. | 2008 | ChemMedChem | pmid:18038381 |
| Damier-Piolle L et al. | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. | 2008 | Antimicrob. Agents Chemother. | pmid:18086852 |
| Sánchez-Tatay D et al. | Antibiotic susceptibility and molecular epidemiology of nasopharyngeal pneumococci from Spanish children. | 2008 | Clin. Microbiol. Infect. | pmid:18727804 |
| Stathi A et al. | Prevalence of emm types 1 and 12 from invasive Streptococcus pyogenes disease in Greece--results of enhanced surveillance. | 2008 | Clin. Microbiol. Infect. | pmid:18727807 |
| Yao S et al. | Erythromycin-induced ribosome stalling and RNase J1-mediated mRNA processing in Bacillus subtilis. | 2008 | Mol. Microbiol. | pmid:18647167 |
| Basnet DB et al. | Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics. | 2008 | J. Biotechnol. | pmid:18430483 |
| Lin CC et al. | Effect of erythromycin on bronchial hyperreactivity and inflammation in ovalbumin-sensitized brown Norway rats. | 2008 | Respir Physiol Neurobiol | pmid:18430615 |
| Steidl R et al. | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. | 2008 | Antimicrob. Agents Chemother. | pmid:18541730 |
| Anderson JF et al. | Antibiotic resistance of enterococci in American bison (Bison bison) from a nature preserve compared to that of Enterococci in pastured cattle. | 2008 | Appl. Environ. Microbiol. | pmid:18245252 |
| Rasi A et al. | Oral erythromycin is ineffective in the treatment of pityriasis rosea. | 2008 | J Drugs Dermatol | pmid:18246696 |
| Takakuwa O et al. | [Successful macrolide therapy for recurrent pneumococcal pneumonia in a man with X-linked agammaglobulinemia]. | 2008 | Nihon Kokyuki Gakkai Zasshi | pmid:18260305 |
| Onuki H et al. | Chemical constituents and diversity of Ligularia lankongensis in Yunnan Province of China. | 2008 | J. Nat. Prod. | pmid:18260639 |
| Gentry DR and Holmes DJ | Selection for high-level telithromycin resistance in Staphylococcus aureus yields mutants resulting from an rplB-to-rplV gene conversion-like event. | 2008 | Antimicrob. Agents Chemother. | pmid:18195060 |
| Besier S et al. | Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. | 2008 | Antimicrob. Agents Chemother. | pmid:18212098 |
| Tsuda T et al. | Effect of 14-membered-ring macrolides on production of interleukin-8 mediated by protease-activated receptor 2 in human keratinocytes. | 2008 | Antimicrob. Agents Chemother. | pmid:18212111 |
| Bommakanti AS et al. | Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae. | 2008 | RNA | pmid:18218702 |
| El Zein N et al. | VIP differentially activates beta2 integrins, CR1, and matrix metalloproteinase-9 in human monocytes through cAMP/PKA, EPAC, and PI-3K signaling pathways via VIP receptor type 1 and FPRL1. | 2008 | J. Leukoc. Biol. | pmid:18174366 |
| Feld L et al. | Selective pressure affects transfer and establishment of a Lactobacillus plantarum resistance plasmid in the gastrointestinal environment. | 2008 | J. Antimicrob. Chemother. | pmid:18238887 |
| Shoji H et al. | Hypertrophic pyloric stenosis in mono-ovular extremely preterm twins after use of erythromycin. | 2008 | Pediatr Int | pmid:19261125 |
| Purdy S and Deberker D | Acne vulgaris. | 2008 | BMJ Clin Evid | pmid:19450306 |
| Wang Y et al. | High frequency transformation of the industrial erythromycin-producing bacterium Saccharopolyspora erythraea. | 2008 | Biotechnol. Lett. | pmid:17922209 |
| Achard A et al. | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. | 2008 | Antimicrob. Agents Chemother. | pmid:18519724 |
| Hutson PR et al. | Effect of medical castration on CYP3A4 enzyme activity using the erythromycin breath test. | 2008 | Cancer Chemother. Pharmacol. | pmid:17922273 |
| Yasuda K et al. | A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine. | 2008 | Drug Metab. Dispos. | pmid:18505790 |
| Schwaiger K and Bauer J | Detection of the erythromycin rRNA methylase gene erm(A) in Enterococcus faecalis. | 2008 | Antimicrob. Agents Chemother. | pmid:18505854 |
| Caldwell DB et al. | Development, stability, and molecular mechanisms of macrolide resistance in Campylobacter jejuni. | 2008 | Antimicrob. Agents Chemother. | pmid:18779354 |
| Vartzelis G et al. | Lemierre's syndrome and defensive antibiotic prescribing tactics: lessons to be had. | 2008 | Clin Pediatr (Phila) | pmid:18509153 |
| Franke RM et al. | Influence of solute carriers on the pharmacokinetics of CYP3A4 probes. | 2008 | Clin. Pharmacol. Ther. | pmid:18509328 |
| Huang G et al. | [Rapid detection of oxacillin and erythromycin resistance genes in Staphylococcus aureus using multiplex PCR]. | 2008 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:18495583 |
| Wahab HA et al. | Refinement of a low-resolution crystal structure to better understand erythromycin interactions on large ribosomal subunit. | 2008 | J. Biomol. Struct. Dyn. | pmid:18533733 |
| Saha S et al. | Enhancement of the efficacy of erythromycin in multiple antibiotic-resistant gram-negative bacterial pathogens. | 2008 | J. Appl. Microbiol. | pmid:18452533 |
| Deane A and Young R | Comment on: The use of erythromycin as a gastrointestinal prokinetic agent in adult critical care: benefits versus risks. | 2008 | J. Antimicrob. Chemother. | pmid:17981832 |
| Ehsanipoor RM et al. | A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes. | 2008 | Am. J. Obstet. Gynecol. | pmid:18455521 |
| Pedersen JM et al. | Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | 2008 | J. Med. Chem. | pmid:18457386 |
| Danilchanka O et al. | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. | 2008 | Antimicrob. Agents Chemother. | pmid:18458127 |
| Li D et al. | Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model. | 2008 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:17826359 |
| Lin HC et al. | Group A streptococcal infection caused by emm1 strains among children in southern Taiwan. | 2008 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:18597127 |
| Balassoulis G et al. | Efficacy and safety of erythromycin as sclerosing agent in patients with recurrent malignant pleural effusion. | 2008 | Am. J. Clin. Oncol. | pmid:18845999 |
| Kim JM et al. | Gene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients. | 2008 | J. Microbiol. Biotechnol. | pmid:18852516 |
| Fujii E et al. | Assessment of the carcinogenic potential of mitemcinal (GM-611): increased incidence of malignant lymphoma in a rat carcinogenicity study. | 2008 | Toxicol. Appl. Pharmacol. | pmid:18355581 |
| Tamura A et al. | The effects of antibiotics on in vitro biofilm model of periodontal disease. | 2008 | Eur. J. Med. Res. | pmid:18948236 |
| Inman JC et al. | Pediatric neck abscesses: changing organisms and empiric therapies. | 2008 | Laryngoscope | pmid:18948832 |
| Kennedy J | Hidradenitis suppurativa: a diagnostic dilemma for sexual health. | 2008 | N. Z. Med. J. | pmid:18791629 |
| Oda M et al. | Effect of erythromycin on biological activities induced by clostridium perfringens alpha-toxin. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18794379 |
| Heightman TD et al. | Identification of small molecule agonists of the motilin receptor. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18980843 |
| Li T et al. | [Antimicrobial effects of erythromycin microspheres against Mycoplasma Pneumoniae in rats]. | 2008 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:18971193 |
| Sadeghi-Khomami A et al. | Glycosidase inhibition by macrolide antibiotics elucidated by STD-NMR spectroscopy. | 2008 | Chem. Biol. | pmid:18635010 |
| Koenig JB et al. | Use of multichannel electrointestinography for noninvasive assessment of myoelectrical activity in the cecum and large colon of horses. | 2008 | Am. J. Vet. Res. | pmid:18518649 |
| Hung SW et al. | Antibiotic susceptibility and prevalence of erythromycin ribosomal methylase gene, erm(B) in Streptococcus spp. | 2008 | Vet. J. | pmid:17400007 |
| Miller AA et al. | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. | 2008 | Antimicrob. Agents Chemother. | pmid:18519725 |
| De Munain JL et al. | Two lymphogranuloma venereum cases in a heterosexual couple in Bilbao (Spain). | 2008 | Sex Transm Dis | pmid:18641534 |
| Lordan JT et al. | An investigative technique to distinguish between the gastrojejunostomy and the hepaticojejunostomy as the cause of cholangitis following pancreaticoduodenectomy. | 2008 | Ann R Coll Surg Engl | pmid:18642429 |
| Horner P | Chlamydia (uncomplicated, genital). | 2008 | BMJ Clin Evid | pmid:19450291 |
| Wolff BJ et al. | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. | 2008 | Antimicrob. Agents Chemother. | pmid:18644962 |
| Ng E and Shah VS | Erythromycin for the prevention and treatment of feeding intolerance in preterm infants. | 2008 | Cochrane Database Syst Rev | pmid:18646077 |
| Emaneini M et al. | Characterization of glycopeptides, aminoglycosides and macrolide resistance among Enterococcus faecalis and Enterococcus faecium isolates from hospitals in Tehran. | 2008 | Pol. J. Microbiol. | pmid:18646406 |
| Turley AJ et al. | Acute myocarditis secondary to Campylobacter jejuni enterocolitis. | 2008 | Resuscitation | pmid:18617316 |
| Gallerani M and Boari B | Hallucinations and tremors due to oral therapeutic doses of erythromycin and methylprednisolone. | 2008 | Intern Emerg Med | pmid:18270792 |
| Ge Y et al. | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. | 2008 | Antimicrob. Agents Chemother. | pmid:18625769 |
| Lawrence L et al. | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. | 2008 | Antimicrob. Agents Chemother. | pmid:18316525 |
| Diwakar SD et al. | Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18650090 |
| Koh EH et al. | Decrease of erythromycin resistance in group A streptococci by change of emm distribution. | 2008 | Jpn. J. Infect. Dis. | pmid:18653965 |
| Portilla-Arias JA et al. | Synthesis, degradability, and drug releasing properties of methyl esters of fungal poly(beta,L-malic acid). | 2008 | Macromol Biosci | pmid:18322913 |
| Auw-Hädrich C | [From dry eye to keratitis. Often overlooked: ocular rosacea] [interview by Waldtraud Paukstadt]. | 2008 | MMW Fortschr Med | pmid:18323337 |
| Kennedy W | Case of the month. Pitted keratolysis. | 2008 | JAAPA | pmid:18323358 |
| Jeyaraj D et al. | I(Kr) channel blockade to unmask occult congenital long QT syndrome. | 2008 | Heart Rhythm | pmid:18273958 |
| Pendela M et al. | Combination of a liquid chromatography-ultraviolet method with a non-volatile eluent, peak trapping and a liquid chromatography-mass spectrometry method with a volatile eluent to characterise erythromycin related substances. | 2008 | J Chromatogr A | pmid:18177878 |
| Kenyon S et al. | MRC ORACLE Children Study. Long term outcomes following prescription of antibiotics to pregnant women with either spontaneous preterm labour or preterm rupture of the membranes. | 2008 | BMC Pregnancy Childbirth | pmid:18435833 |
| Sedgley CM et al. | Antibiotic resistance gene transfer between Streptococcus gordonii and Enterococcus faecalis in root canals of teeth ex vivo. | 2008 | J Endod | pmid:18436036 |
| Wang Y and Pfeifer BA | 6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli. | 2008 | Metab. Eng. | pmid:17959404 |
| Waites KB et al. | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. | 2008 | Antimicrob. Agents Chemother. | pmid:18663020 |
| Bukhari IA | Oral erythromycin is ineffective in the treatment of pityriasis rosea. | 2008 | J Drugs Dermatol | pmid:18664152 |
| Lin S et al. | A school-based program for control of group a streptococcal upper respiratory tract infections: a controlled trial in Southern China. | 2008 | Pediatr. Infect. Dis. J. | pmid:18664988 |
| Kim JS et al. | Differential effects of temperature on natural transformation to erythromycin and nalidixic acid resistance in Campylobacter coli. | 2008 | Appl. Environ. Microbiol. | pmid:18708520 |
| Zou X et al. | Application of oxygen uptake rate and response surface methodology for erythromycin production by Saccharopolyspora erythraea. | 2008 | J. Ind. Microbiol. Biotechnol. | pmid:18709395 |
| Jones-Caballero M et al. | Self-reported adherence to treatment and quality of life in mild to moderate acne. | 2008 | Dermatology (Basel) | pmid:18714158 |
| Zmantar T et al. | Multiplex PCR detection of the antibiotic resistance genes in Staphylococcus aureus strains isolated from auricular infections. | 2008 | Folia Microbiol. (Praha) | pmid:18759121 |
| Warner DM et al. | Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness. | 2008 | Mol. Microbiol. | pmid:18761689 |
| Tang D et al. | Design, synthesis, and antibacterial activities of novel 3,6-bicyclolide oximes: length optimization and zero carbon linker oximes. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18762418 |
| Hsieh YC et al. | Clonal spread of highly beta-lactam-resistant Streptococcus pneumoniae isolates in Taiwan. | 2008 | Antimicrob. Agents Chemother. | pmid:18413298 |
| Thompson PL et al. | Has UK guidance affected general practitioner antibiotic prescribing for otitis media in children? | 2008 | J Public Health (Oxf) | pmid:18765405 |
| Katri N et al. | Abrogation of the resistance of choline-induced Pseudomonas aeruginosa virulence to sub-MIC erythromycin by ethanol. | 2008 | ISME J | pmid:18754042 |
| Bala I et al. | Effect of preoperative oral erythromycin, erythromycin-ranitidine, and ranitidine-metoclopramide on gastric fluid pH and volume. | 2008 | J Clin Anesth | pmid:18346606 |
| Mitselos A et al. | Differences in motilin receptor desensitization after stimulation with motilin or motilides are due to alternative receptor trafficking. | 2008 | Biochem. Pharmacol. | pmid:18096134 |
| Nishio N et al. | Cat scratch disease with encephalopathy in a 9-year-old girl. | 2008 | Pediatr Int | pmid:19067901 |
| John T and Shah AA | Use of azithromycin ophthalmic solution in the treatment of chronic mixed anterior blepharitis. | 2008 | Ann Ophthalmol (Skokie) | pmid:19013912 |
| Watanabe K et al. | Drug-resistant pneumococci in children with acute lower respiratory infections in Vietnam. | 2008 | Pediatr Int | pmid:19143975 |
| El-Enshasy HA et al. | Improvement of erythromycin production by Saccharopolyspora erythraea in molasses based medium through cultivation medium optimization. | 2008 | Bioresour. Technol. | pmid:17936622 |
| Wang C et al. | Non-fusion and fusion expression of beta-galactosidase from Lactobacillus bulgaricus in Lactococcus lactis. | 2008 | Biomed. Environ. Sci. | pmid:19133612 |
| Wittek T et al. | Effect of preoperative erythromycin or dexamethasone/vitamin C on postoperative abomasal emptying rate in dairy cows undergoing surgical correction of abomasal volvulus. | 2008 | Vet Surg | pmid:19134103 |
| Singh GM et al. | beta-Hydroxylation of the aspartyl residue in the phytotoxin syringomycin E: characterization of two candidate hydroxylases AspH and SyrP in Pseudomonas syringae. | 2008 | Biochemistry | pmid:18826255 |
| Petropoulos AD et al. | Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. | 2008 | J. Biol. Chem. | pmid:18079110 |