erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Zhang RL et al. | [Study on interventional methods and the pattern of maternal-fetal transmission of syphilis during pregnancy]. | 2007 | Zhonghua Fu Chan Ke Za Zhi | pmid:17961330 |
Xia AF | [Effect of oculentum erythromycin in the prevention of inflammatory conjunctivitis of neonates]. | 1993 | Zhonghua Hu Li Za Zhi | pmid:8339361 |
Li X | [Combination of commonly used antibiotics in intravenous infusions]. | 1991 | Zhonghua Hu Li Za Zhi | pmid:1889101 |
Yin YD et al. | [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24503430 |
Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
Yu L and Ran PX | [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. | 2009 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:19567187 |
Xiao W et al. | [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. | 2000 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11778516 |
Tan W et al. | [The mechanism and effect of erythromycin in development of pulmonary fibrosis]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11812357 |
Zhong XN and Guo SM | [An experimental study on pulmonary vascular inflammation in a rat model of chronic bronchitis and emphysema]. | 2006 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:17045040 |
Liu J et al. | [mRNA expression of basic fibroblast growth factor in the pulmonary tissues from rats repeatedly infected with mycoplasma pneumoniae]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11775917 |