erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
Zmantar T et al. | Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. | 2016 | Microb. Pathog. | pmid:27816681 |
Barbanti F and Spigaglia P | Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. | 2016 | Anaerobe | pmid:27725230 |
Mayor-Ibarguren A et al. | Periorificial Lesions in a Young Girl. | 2016 | Actas Dermosifiliogr | pmid:26935746 |
Parasrampuria DA et al. | Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. | 2016 | Br J Clin Pharmacol | pmid:27530188 |
Hua CZ et al. | [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:27510868 |
Johanesen P and Lyras D | Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. | 2016 | Methods Mol. Biol. | pmid:27507343 |
Mikhail M et al. | Orbital cellulitis and multiple abscess formation after strabismus surgery. | 2016 | Can. J. Ophthalmol. | pmid:27085279 |
Chen Y et al. | TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. | 2016 | Carbohydr Polym | pmid:27083368 |
Del Grosso M et al. | ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. | 2016 | Antimicrob. Agents Chemother. | pmid:27067338 |
Shi HY et al. | [Effect of quorum sensing system on the infection of MRSA and the intervention of erythromycin on it]. | 2016 | Zhonghua Yi Xue Za Zhi | pmid:27760665 |
Katayama Y et al. | Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. | 2016 | Neurol. Res. | pmid:27078702 |
Li M et al. | Sugar-Grafted Cyclodextrin Nanocarrier as a "Trojan Horse" for Potentiating Antibiotic Activity. | 2016 | Pharm. Res. | pmid:26792570 |
Lapierre L et al. | Characterization of Antimicrobial Susceptibility and Its Association with Virulence Genes Related to Adherence, Invasion, and Cytotoxicity in Campylobacter jejuni and Campylobacter coli Isolates from Animals, Meat, and Humans. | 2016 | Microb. Drug Resist. | pmid:26779841 |
Pan M and Chu LM | Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. | 2016 | Ecotoxicol. Environ. Saf. | pmid:26773832 |
Rodrigues S et al. | Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. | 2016 | Sci. Total Environ. | pmid:26760278 |
Nenquin M and Henquin JC | Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells. | 2016 | Diabetes Obes Metab | pmid:26584950 |
Wu H et al. | In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26552796 |
Boetsch C et al. | Effects of Cytochrome P450 3A4 Inhibitors-Ketoconazole and Erythromycin-on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions. | 2016 | Clin Pharmacokinet | pmid:26341813 |
Giuliano MW and Miller SJ | Site-Selective Reactions with Peptide-Based Catalysts. | 2016 | Top Curr Chem | pmid:26307403 |