erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Uremia D014511 33 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Acne Vulgaris D000152 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Heart Failure D006333 36 associated lipids
Lung Diseases D008171 37 associated lipids
Nervous System Diseases D009422 37 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Hypotension D007022 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Arthritis D001168 41 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Psoriasis D011565 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Leukemia D007938 74 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Weight Gain D015430 101 associated lipids
Hypertension D006973 115 associated lipids
Inflammation D007249 119 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Wapnick S et al. Reduction of postoperative infection in elective colon surgery with preoperative administration of kanamycin and erythromycin. 1979 Surgery pmid:371048
Pennathur A et al. Erythromycin, motilin, and the esophagus. 1993 Surgery pmid:8342132
Bell GA et al. Prophylactic antibiotics in elective colon surgery. 1983 Surgery pmid:6849206
Hocking MP Postoperative gastroparesis and tachygastria--response to electric stimulation and erythromycin. 1993 Surgery pmid:8367808
Kaufman HS et al. The effect of erythromycin on motility of the duodenum, sphincter of Oddi, and gallbladder in the prairie dog. 1993 Surgery pmid:8367809
Cohen SR et al. Healing of ischemic colonic anastomoses in the rat: role of antibiotic preparation. 1985 Surgery pmid:3983820
Parry SW et al. Acalculous hypersensitivity cholecystitis: hypothesis of a new clinicopathologic entity. 1988 Surgery pmid:3187904
Hinchey EJ et al. Metronidazole as a prophylactic agent in wound infection after colon surgery. 1983 Surgery pmid:6336863
Nishikawa K et al. Functional characteristics of the pylorus in patients undergoing pylorus--preserving gastrectomy for early gastric cancer. 2002 Surgery pmid:12075173
SANTESSON G [Metastatic lung infiltrate in a case of coli- and staphylococcic septicemia, which was treated with erythromycin and tetracycline]. 1956 Sven Lakartidn pmid:13311778
HEDENIUS P and TUNEVALL HG [Erythromycin, its antibacterial effect in vitro, its absorption and excretion, with a preliminary report on a series of cases with erythromycin therapy]. 1953 Sven Lakartidn pmid:13113605
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Wilkie D Analysis of mitochondrial drug resistance in Saccharomyces cerevisiae. 1970 Symp. Soc. Exp. Biol. pmid:5516345
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Tanaka H [Receptor agonists and antagonists: the present and future]. 1993 Tanpakushitsu Kakusan Koso pmid:8210427
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StrachunskiÄ­ LS et al. [Rovamycin (spiramycin)--a macrolide antibiotic for intravenous administration: a trial in the treatment of pneumonia]. 1995 Ter. Arkh. pmid:7770811
Milevskaia IuL [Complex use of tetracycline and erythromycin in the therapy of internal diseases and hematology]. 1971 Ter. Arkh. pmid:5117924
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Djokić S and Tamburasĕv Z Erythromycin study: 9-amino-3-O-cladinosyl-5-O-desosaminyl-6,11,12-tryhydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide. 1967 Tetrahedron Lett. pmid:6047192
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Demarco PV Pyridine solvent shifts in the NMR analysis of etythromycin aglycones. 1969 Tetrahedron Lett. pmid:5779748
Perun TJ and Egan RS The conformation of erythromycin aglycones. 1969 Tetrahedron Lett. pmid:5779749
Alexander RE and Grogan DM Long-acting erythromycins: assessing their role in treating outpatient odontogenic infections. 2009 Tex Dent J pmid:19472551
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Farris JR et al. Chancroid in Dallas: new lessons from an old disease. 1991 Tex Med pmid:1882362
Manning RJ Hemorrhage secondary to Campylobacter enterocolitis: conservative care. 1986 Tex Med pmid:3486490
MULLINS JF Neomycin-erythromycin ointment in the treatment of pyodermas. 1954 Tex State J Med pmid:13169049
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Enyuan Q et al. Erythromycin combined with corticosteroid reduced inflammation and modified trauma-induced tracheal stenosis in a rabbit model. Ther Adv Respir Dis pmid:29781361