erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Liu BY et al. | Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. | 2011 | Ecotoxicol. Environ. Saf. | pmid:21353704 |
Crivellaro S et al. | Surveillance of methicillin-resistant Staphylococcus aureus isolated in Torino (northwest Italy). | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21353947 |
Kafali H et al. | Recurrence of ovarian cyst after sclerotherapy. | 2011 | Minerva Ginecol | pmid:21311417 |
Shang Y et al. | Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis. | 2011 | Chin. Med. J. | pmid:21362305 |
Pateron D et al. | Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial. | 2011 | Ann Emerg Med | pmid:21333385 |
Werner CR et al. | [Unexpected complication following esophageal variceal hemorrhage - Case 2/2011]. | 2011 | Dtsch. Med. Wochenschr. | pmid:21271486 |
Wright AJ et al. | The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers. | 2011 | CMAJ | pmid:21242274 |
Zhang L et al. | Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. | 2011 | J. Antibiot. | pmid:21245870 |
Nielsen EI et al. | Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. | 2011 | Antimicrob. Agents Chemother. | pmid:21807983 |
Gardner L et al. | Photochemical control of bacterial signal processing using a light-activated erythromycin. | 2011 | Mol Biosyst | pmid:21785768 |
DeDea L | Erythromycin for GI motility; sunscreens; enoxaparin in obesity. | 2011 | JAAPA | pmid:21850912 |
Maeda Y et al. | Comparison of minimum inhibitory concentration by broth microdilution testing versus standard disc diffusion testing in the detection of penicillin, erythromycin and ciprofloxacin resistance in viridans group streptococci. | 2011 | J. Med. Microbiol. | pmid:21852527 |
Bistrian BR | Enteral feeding: good, but not for everyone. | 2011 | Crit. Care Med. | pmid:21613857 |
Bai Y et al. | Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. | 2011 | Aliment. Pharmacol. Ther. | pmid:21615438 |
Ergin A et al. | Erythromycin and penicillin resistance mechanisms among viridans group streptococci isolated from blood cultures of adult patients with underlying diseases. | 2011 | New Microbiol. | pmid:21617831 |
Garber NC et al. | Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. | 2011 | Adv. Exp. Med. Biol. | pmid:21618111 |
Sugiyama E et al. | The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. | 2011 | J Pharm Sci | pmid:21618542 |
Qin X et al. | Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. | 2011 | Int. J. Antimicrob. Agents | pmid:21549571 |
Akshay S et al. | Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. | 2011 | Antimicrob. Agents Chemother. | pmid:21730122 |
Daram SR and Garretson R | Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. | 2011 | Gastrointest. Endosc. | pmid:21704823 |
Ma X et al. | Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation. | 2011 | Eur J Med Chem | pmid:21855183 |
Soehnlen MK et al. | In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. | 2011 | J. Vet. Diagn. Invest. | pmid:21908288 |
Brodesser S and Kolter T | Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. | 2011 | J Lipids | pmid:21490810 |
Spurling GK et al. | Antibiotics for bronchiolitis in children. | 2011 | Cochrane Database Syst Rev | pmid:21678346 |
Matsson EM et al. | Biliary excretion of ximelagatran and its metabolites and the influence of erythromycin following intraintestinal administration to healthy volunteers. | 2011 | J Clin Pharmacol | pmid:20663994 |
Miller E et al. | Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. | 2011 | Lancet Infect Dis | pmid:21621466 |
Song W et al. | A novel strontium-doped calcium polyphosphate/erythromycin/poly(vinyl alcohol) composite for bone tissue engineering. | 2011 | J Biomed Mater Res A | pmid:21626667 |
Wingard JB et al. | A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. | 2011 | Antimicrob. Agents Chemother. | pmid:21628536 |
Amachawadi RG et al. | Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. | 2011 | Appl. Environ. Microbiol. | pmid:21705534 |
Ma L et al. | Green fluorescent protein labeling of Listeria, Salmonella, and Escherichia coli O157:H7 for safety-related studies. | 2011 | PLoS ONE | pmid:21483738 |
Xiong L et al. | Lignans and neolignans from Sinocalamus affinis and their absolute configurations. | 2011 | J. Nat. Prod. | pmid:21469695 |
Lobanov KV et al. | Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications. | 2011 | Acta Naturae | pmid:22649686 |
Aknin LB et al. | It's the recipient that counts: spending money on strong social ties leads to greater happiness than spending on weak social ties. | 2011 | PLoS ONE | pmid:21347326 |
Siibak T et al. | Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. | 2011 | Mol. Microbiol. | pmid:21320180 |
Veiga-Crespo P et al. | Synergism between outer membrane proteins and antimicrobials. | 2011 | Antimicrob. Agents Chemother. | pmid:21321143 |
Gray KL et al. | The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21982562 |
Sedighi I et al. | Nasal carriage of methicillin resistant Staphylococcus aureus and their antibiotic susceptibility patterns in children attending day-care centers. | 2011 | Acta Microbiol Immunol Hung | pmid:21983324 |
Meinertz JR et al. | Chronic toxicity of erythromycin thiocyanate to Daphnia magna in a flow-through, continuous exposure test system. | 2011 | Bull Environ Contam Toxicol | pmid:21984684 |
Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
Padovan J et al. | Investigating the barriers to bioavailability of macrolide antibiotics in the rat. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:22113743 |
Walkey AJ and Wiener RS | Macrolide antibiotics and survival in patients with acute lung injury. | 2012 | Chest | pmid:22116799 |
Segatore B et al. | In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods. | 2012 | Phytomedicine | pmid:22119041 |
Sugimoto T et al. | Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. | 2012 | Bioorg. Med. Chem. | pmid:22925450 |
De Francesco MA et al. | Phenotypes, genotypes, serotypes and molecular epidemiology of erythromycin-resistant Streptococcus agalactiae in Italy. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22120421 |
Sugimoto T et al. | Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858102 |
Zou MX et al. | Antimicrobial resistance and molecular epidemiological characteristics of clinical isolates of Staphylococcus aureus in Changsha area. | 2012 | Chin. Med. J. | pmid:22882850 |
Weber JM et al. | An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22048617 |
Dekio I | Follicular spicules associated with Propionibacterium acnes with response to erythromycin: Lack of evidence for the species? | 2012 | J. Dermatol. | pmid:22224953 |
Malnick SD and Melzer E | Compromise of patient safety in research report. | 2012 | J. Clin. Gastroenterol. | pmid:22227732 |
Popowska M et al. | Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes. | 2012 | Antimicrob. Agents Chemother. | pmid:22203596 |
McCusker KP and Fujimori DG | The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. | 2012 | ACS Chem. Biol. | pmid:22208312 |
März A et al. | Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. | 2012 | Anal Bioanal Chem | pmid:21822777 |
Biester EM et al. | Identification of avian wax synthases. | 2012 | BMC Biochem. | pmid:22305293 |
Jaglic Z et al. | Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. | 2012 | Zoonoses Public Health | pmid:21843202 |
Shiu WK et al. | Antibacterial acylphloroglucinols from Hypericum olympicum. | 2012 | J. Nat. Prod. | pmid:21899267 |
Gant CM et al. | Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22751535 |
Kim J et al. | Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. | 2012 | J. Microbiol. | pmid:22752920 |
Boswihi SS et al. | Serotypes and antibiotic resistance in Group B streptococcus isolated from patients at the Maternity Hospital, Kuwait. | 2012 | J. Med. Microbiol. | pmid:21903822 |
Arakawa K et al. | The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. | 2012 | Chembiochem | pmid:22761035 |
Carbonero A et al. | Campylobacter spp., C. jejuni and C. upsaliensis infection-associated factors in healthy and ill dogs from clinics in Cordoba, Spain. Screening tests for antimicrobial susceptibility. | 2012 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:22640550 |
Sadeghi SJ et al. | Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. | 2012 | Bioelectrochemistry | pmid:22480862 |
Nunoi H et al. | A relationship between motilin and growth hormone secretagogue receptors. | 2012 | Regul. Pept. | pmid:22465164 |
De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
Bosnar M et al. | N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity. | 2012 | J. Med. Chem. | pmid:22697905 |
Yiannakopoulou E et al. | Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review. | 2012 | Surg Laparosc Endosc Percutan Tech | pmid:22678313 |
Bai J et al. | Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. | 2012 | Mediators Inflamm. | pmid:22701274 |
Pollett S et al. | Campylobacter antimicrobial resistance in Peru: a ten-year observational study. | 2012 | BMC Infect. Dis. | pmid:22898609 |
Licona-Cassani C et al. | Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. | 2012 | Antonie Van Leeuwenhoek | pmid:22847261 |
Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. | 2012 | Prescrire Int | pmid:22852287 | |
Kim EY et al. | The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. | 2012 | Acta Radiol | pmid:22855416 |
Oldenburg M et al. | TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. | 2012 | Science | pmid:22821982 |
Feng Z et al. | Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations. | 2012 | Mol Biosyst | pmid:22825052 |
Maeda Y et al. | UV-C-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents. | 2012 | J Investig Clin Dent | pmid:22887906 |
Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
Perry DM et al. | Identification and characterization of protein phosphatase 2C activation by ceramide. | 2012 | J. Lipid Res. | pmid:22615346 |
Geddes BA and Oresnik IJ | Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. | 2012 | Microbiology (Reading, Engl.) | pmid:22609752 |
Wauters J et al. | A Novel Method (CiMON) for Continuous Intra-Abdominal Pressure Monitoring: Pilot Test in a Pig Model. | 2012 | Crit Care Res Pract | pmid:22454765 |
Aiello A et al. | Aplisulfamines, new sulfoxide-containing metabolites from an aplidium tunicate: absolute stereochemistry at chiral sulfur and carbon atoms assigned through an original combination of spectroscopic and computational methods. | 2012 | Mar Drugs | pmid:22363220 |
Molnari JC and Myers AL | Carbonyl reduction of bupropion in human liver. | 2012 | Xenobiotica | pmid:22339467 |
Senhorinho GN et al. | Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. | 2012 | Anaerobe | pmid:22609780 |
Bidet P et al. | Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22610663 |
Lu X et al. | Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms. | 2012 | J. Antimicrob. Chemother. | pmid:22550133 |
Bistrian BR | The who, what, where, when, why, and how of early enteral feeding. | 2012 | Am. J. Clin. Nutr. | pmid:22552029 |
Noto MJ and Wheeler AP | Macrolides for acute lung injury. | 2012 | Chest | pmid:22553255 |
Liu X et al. | [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. | 2012 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:23156807 |
Chen X et al. | Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23122862 |
Klibi N et al. | Genotypic diversity, antibiotic resistance and bacteriocin production of enterococci isolated from rhizospheres. | 2012 | Microbes Environ. | pmid:23124764 |
Guan Y et al. | [Preliminary study of effects of andrographolide on Staphylococcus epidermidis biofilms]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23126203 |
Kelley C et al. | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. | 2012 | Bioorg. Med. Chem. | pmid:23127490 |
Parhi A et al. | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23084900 |
El Hafidi N et al. | [Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis]. | 2012 | Rev. Neurol. (Paris) | pmid:22244792 |
Tolosa L et al. | Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | 2012 | Toxicol. Sci. | pmid:22331495 |
Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. | 2012 | Am Fam Physician | pmid:22335221 | |
Jordan PA and Miller SJ | An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22319027 |
Lenglet A et al. | Surveillance status and recent data for Mycoplasma pneumoniae infections in the European Union and European Economic Area, January 2012. | 2012 | Euro Surveill. | pmid:22321134 |
Blystad H et al. | Increased incidence of Mycoplasma pneumoniae infection in Norway 2011. | 2012 | Euro Surveill. | pmid:22321136 |
Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |
Waseem S et al. | Spectrum of gastroparesis in children. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22314391 |
Koning S et al. | Interventions for impetigo. | 2012 | Cochrane Database Syst Rev | pmid:22258953 |