erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Brünker P et al. | Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla haemoglobin gene (vhb). | 1998 | Microbiology (Reading, Engl.) | pmid:9782491 |
Jacobsen JR et al. | Precursor-directed biosynthesis of 12-ethyl erythromycin. | 1998 | Bioorg. Med. Chem. | pmid:9784859 |
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Oh TG et al. | Induction of ermAMR from a clinical strain of Enterococcus faecalis by 16-membered-ring macrolide antibiotics. | 1998 | J. Bacteriol. | pmid:9791136 |
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Danias PG et al. | Comparative in vitro and in vivo efficacy of roxithromycin and erythromycin against a strain of methicillin-susceptible Staphylococcus epidermidis. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791758 |
Riippi M et al. | Dependence between dissolution rate and porosity of compressed erythromycin acistrate tablets. | 1998 | Eur J Pharm Biopharm | pmid:9795044 |
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Champney WS and Burdine R | Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. | 1998 | Microb. Drug Resist. | pmid:9818968 |
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Takano M et al. | Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. | 1998 | Eur. J. Pharmacol. | pmid:9822896 |
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Su BH et al. | Effect of erythromycin on feeding intolerance in very low birth weight infants: a preliminary observation. | 1998 Sep-Oct | Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi | pmid:9823678 |
Xu QW et al. | Altered migrating myoelectrical complex in an animal model of cholesterol gallstone disease: the effect of erythromycin. | 1998 | Gut | pmid:9824610 |
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Jónsson B et al. | Ureaplasma urealyticum, erythromycin and respiratory morbidity in high-risk preterm neonates. | 1998 | Acta Paediatr. | pmid:9825977 |
Larsen B and Glover DD | Serum erythromycin levels in pregnancy. | 1998 Sep-Oct | Clin Ther | pmid:9829448 |
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Khiat A and Boulanger Y | Identification of the motilide pharmacophores using quantitative structure activity relationships. | 1998 | J. Pept. Res. | pmid:9832311 |
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Emond E et al. | AbiQ, an abortive infection mechanism from Lactococcus lactis. | 1998 | Appl. Environ. Microbiol. | pmid:9835558 |
Kinashi H et al. | Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836424 |
Koh TH et al. | Molecular typing of multiresistant Streptococcus pneumoniae serogroup 19 in Singapore. | 1998 | Pathology | pmid:9839316 |