erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Gastroparesis D018589 2 associated lipids
Arthralgia D018771 8 associated lipids
Abdominal Abscess D018784 2 associated lipids
Sepsis D018805 11 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epidural Abscess D020802 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Ileus D045823 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Seroma D049291 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Occupational Injuries D060051 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Henkes M et al. Therapeutic options for chronic myeloid leukemia: focus on imatinib (Glivec, Gleevectrade mark). 2008 Ther Clin Risk Manag pmid:18728706
Miles MV and Tennison MB Erythromycin effects on multiple-dose carbamazepine kinetics. 1989 Ther Drug Monit pmid:2911854
Hedrick R et al. Carbamazepine--erythromycin interaction leading to carbamazepine toxicity in four epileptic children. 1983 Ther Drug Monit pmid:6659014
Wadhwa NK et al. Interaction between erythromycin and cyclosporine in a kidney and pancreas allograft recipient. 1987 Ther Drug Monit pmid:3554626
Watkins PB Erythromycin breath test and clinical transplantation. 1996 Ther Drug Monit pmid:8857552
Buiter HJ et al. Erythromycin precipitation in vena femoralis: investigation of crystals found in postmortem material of an intensive care unit patient. 2008 Ther Drug Monit pmid:18223476
Baciewicz AM Carbamazepine drug interactions. 1986 Ther Drug Monit pmid:3092407
Wadhwa NK et al. Cyclosporine drug interactions: a review. 1987 Ther Drug Monit pmid:3321582
Birkett DJ et al. Single oral dose pharmacokinetics of erythromycin and roxithromycin and the effects of chronic dosing. 1990 Ther Drug Monit pmid:2305423
de Wildt SN et al. 13C-erythromycin breath test as a noninvasive measure of CYP3A activity in newborn infants: a pilot study. 2007 Ther Drug Monit pmid:17417078
Padhi ID et al. Interaction between tacrolimus and erythromycin. 1997 Ther Drug Monit pmid:9029762
Luurila H et al. Lack of interaction of erythromycin with temazepam. 1994 Ther Drug Monit pmid:7878692
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ILKER HG [Not Available]. 1957 Ther Ggw pmid:13422370
Petzoldt D [Current diagnosis and therapy of acquired syphilis]. 1973 Ther Ggw pmid:4708581
Münnich D et al. Observations on micro-encapsulated erythromycin (Eryc capsule) in the treatment of various infections of adults. 1988 Ther Hung pmid:3249998
Ferencz A et al. Use of Eryc capsule in adult patients. 1989 Ther Hung pmid:2686082
RUBANYI P and KOS R ACTUAL PROBLEMS OF ANTIBIOTIC TREATMENT IN SURGICAL PRACTICE. 1963 Ther Hung pmid:14133128
Adám A and Kuberka Z Use of a new erythromycin product--eryc--in the treatment of the lower respiratory tract infections. 1990 Ther Hung pmid:2094053
Hoppe JE [Pertussis: current aspects of diagnosis, therapy and prevention]. 1998 Ther Umsch pmid:9492614
Meyer JC and Eichmann A [Serodiagnosis and therapy of syphilis]. 1985 Ther Umsch pmid:3911474
Korting HC [Urethritis in the male, diagnosis and therapy]. 1985 Ther Umsch pmid:2935962
Lagier G et al. [A minor case of ergotism appearing to be connected with a potentialisation of ergotamine tartrate by erythromycine ethyl-succinate (author's transl)]. 1979 Jul-Aug Therapie pmid:531783
Bergogne-Berezin E et al. [Experimental study of the possible influence of a fluidifying agent (bromhexine) on the penetration of erythromycine into bronchial secretions (author's transl)]. 1979 Nov-Dec Therapie pmid:547444
Baldit C et al. [Influence of a new macrolide, dirithromycine, on the clearance of antipyrine]. 1987 May-Jun Therapie pmid:3660320
Bavoux F [Torsades de pointes and anti-infective agents]. 1992 Sep-Oct Therapie pmid:1299973
VIALLIER J et al. [Study of the blood levels obtained with 2 new esters of erythromycin: propionyl erythromycin and propionyl erythromycin lauryl sulfate]. 1961 Nov-Dec Therapie pmid:13925737
Kanfer A et al. [Erythromycin ototoxicity in patients with renal insufficiency (author's transl)]. 1980 May-Jun Therapie pmid:7423428
Hugues FC et al. [Cochlear toxicity of erythromycin in elderly patients]. 1984 Sep-Oct Therapie pmid:6506017
TREFOUEL J et al. [Not Available]. 1959 Therapie pmid:13647435
Moutard I et al. In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. 1999 Sep-Oct Therapie pmid:10667098
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Yousaf N et al. Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial. 2010 Thorax pmid:20965928
Azuma A et al. Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. 1998 Thorax pmid:9659353
Waterworth PM et al. A critical investigation into the antibiotic sterilization of heart valve homografts. 1974 Thorax pmid:4368321
Dorrell L et al. Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. 1994 Thorax pmid:8016806
White RJ Why use erythromycin? 1994 Thorax pmid:7974308
Oaklay CM Prevention of infective endocarditis. 1979 Thorax pmid:542909
Brennan S et al. Directed neutrophil migration to IL-8 is increased in cystic fibrosis: a study of the effect of erythromycin. 2001 Thorax pmid:11120907
Ellis ME and Dunbar EM In vivo response of acute Q fever to erythromycin. 1982 Thorax pmid:7164010
Domingo C et al. Radiographic appearance of nosocomial legionnaires' disease after erythromycin treatment. 1991 Thorax pmid:1948796
Venkatesan P et al. A hospital study of community acquired pneumonia in the elderly. 1990 Thorax pmid:2356552
Fujii T et al. Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. 1995 Thorax pmid:8553295
Guest PJ et al. Pulmonary Mycobacterium kansasii infection successfully treated with a regimen containing erythromycin. 1988 Thorax pmid:3420563
Brugiere O et al. Diffuse panbronchiolitis in an Asian immigrant. 1996 Thorax pmid:8977613
Marlin GE et al. Plasma and sputum erythromycin concentrations in chronic bronchitis. 1980 Thorax pmid:7434299
Koyama H and Geddes DM Erythromycin and diffuse panbronchiolitis. 1997 Thorax pmid:9404381
Sobradillo V et al. Antibiotic treatment in pneumonia due to Q fever. 1992 Thorax pmid:1585291
McCulloch AJ et al. Severe steroid responsive pneumonitis associated with pyoderma gangrenosum and ulcerative colitis. 1985 Thorax pmid:4023983
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400