erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Gastroparesis D018589 2 associated lipids
Arthralgia D018771 8 associated lipids
Abdominal Abscess D018784 2 associated lipids
Sepsis D018805 11 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epidural Abscess D020802 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Ileus D045823 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Seroma D049291 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Occupational Injuries D060051 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Nie XP et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. 2013 Environ. Pollut. pmid:22982550
Ishihara K et al. Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. 2013 Microbiol. Immunol. pmid:23930694
Pedersen JM et al. Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). 2013 Toxicol. Sci. pmid:24014644
Zhang L et al. Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23937982
Herath SC and Poole P Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 2013 Cochrane Database Syst Rev pmid:24288145
Liang JH and Han X Structure-activity relationships and mechanism of action of macrolides derived from erythromycin as antibacterial agents. 2013 Curr Top Med Chem pmid:24200358
Matejcek A and Goldman RD Treatment and prevention of ophthalmia neonatorum. 2013 Can Fam Physician pmid:24235191
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Wu C et al. Identification of elaiophylin derivatives from the marine-derived actinomycete Streptomyces sp. 7-145 using PCR-based screening. 2013 J. Nat. Prod. pmid:24164206
Arao M et al. Clostridium difficile colitis induced by long-term low-dosage erythromycin. 2013 Pediatr. Infect. Dis. J. pmid:24008746
Kirm B et al. SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. 2013 Microb. Cell Fact. pmid:24341557
Olender A et al. The cause of Actinomyces canalictulis--a case study. 2013 Ann Agric Environ Med pmid:24364446
Yin YD et al. [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. 2013 Zhonghua Jie He He Hu Xi Za Zhi pmid:24503430
Koulaouzidis A et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. 2013 Curr Med Res Opin pmid:23790243
Lin MH et al. Penetration of erythromycin through Staphylococcus epidermidis biofilm. 2013 Chin. Med. J. pmid:23876889
Winnicka K et al. The effect of PAMAM dendrimers on the antibacterial activity of antibiotics with different water solubility. 2013 Molecules pmid:23881050
Hennenberg M et al. The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction. 2013 J. Biomed. Sci. pmid:23815815
Mu Y et al. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. 2013 Antimicrob. Agents Chemother. pmid:23817373
Mu X et al. Effects of erythromycin and rifampicin on immunomodulatory gene expression and cellular function in human polymorphonuclear leukocytes. 2013 Chemotherapy pmid:24852442
Oplinger RW and Wagner EJ Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. 2013 J. Aquat. Anim. Health pmid:23241009
Chae HS et al. Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate. 2013 Appl. Environ. Microbiol. pmid:23241984
Papapetropoulos N et al. Abscesses and wound infections due to Staphylococcus lugdunensis: report of 16 cases. 2013 Infection pmid:23242962
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Juntunen P et al. Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. 2013 J. Appl. Microbiol. pmid:23282197
Liang JH et al. Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. 2013 Bioorg. Med. Chem. Lett. pmid:23375796
Drago L et al. Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. 2013 Int. J. Antimicrob. Agents pmid:23313535
Sanger GJ et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. 2013 Br. J. Pharmacol. pmid:23189978
Rams TE et al. Antibiotic susceptibility of periodontal Enterococcus faecalis. 2013 J. Periodontol. pmid:23106507
Osterman IA et al. A nascent proteome study combining click chemistry with 2DE. 2013 Proteomics pmid:23161590
Chan BC et al. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. 2013 Phytomedicine pmid:23541215
Tarran R et al. Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. 2013 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:23542952
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2013 Cochrane Database Syst Rev pmid:23543536
Moriya S et al. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. 2013 Int. J. Oncol. pmid:23546223
Akiyoshi T et al. Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. 2013 Drug Metab. Pharmacokinet. pmid:23514827
Müller W et al. German Francisella tularensis isolates from European brown hares (Lepus europaeus) reveal genetic and phenotypic diversity. 2013 BMC Microbiol. pmid:23517149
Litvinchuk AV et al. Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. 2013 Apr-May Eur. J. Cell Biol. pmid:23523087
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
Theivanayagam S et al. Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045593
Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
Shim J et al. Clinical inquiry: what is the best treatment for impetigo ? 2014 J Fam Pract pmid:25061625
Krishnappa LG et al. Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. 2014 Acta Microbiol Immunol Hung pmid:24939685
Pasquini L et al. Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. 2014 Sci. Total Environ. pmid:24631609
Abarzúa F et al. [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at Clínica Alemana Temuco, Southern Chile]. 2014 Rev Chilena Infectol pmid:25146205
Jing YR et al. The synthesis of novel taxoids for oral administration. 2014 Bioorg. Med. Chem. pmid:24332858
Borbón-Esquer EM et al. SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. 2014 Scand. J. Infect. Dis. pmid:24832853
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989