erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chen D et al. | Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. | 2014 | PLoS ONE | pmid:25250723 |
Cetecioglu Z | Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24146324 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Nikolay R et al. | Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. | 2014 | Nucleic Acids Res. | pmid:24792169 |
Sanamrad A et al. | Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25056965 |
Shim J et al. | Clinical inquiry: what is the best treatment for impetigo ? | 2014 | J Fam Pract | pmid:25061625 |
Krishnappa LG et al. | Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. | 2014 | Acta Microbiol Immunol Hung | pmid:24939685 |
Barbosa TM et al. | A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. | 2014 | PLoS ONE | pmid:25548909 |
Hudson BH and Zaher HS | Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. | 2014 | Mol. Cell | pmid:25514181 |
Pinto TC et al. | Conjugative transfer of resistance determinants among human and bovine Streptococcus agalactiae. | 2014 | Braz. J. Microbiol. | pmid:25477908 |
Källén B and Danielsson BR | Fetal safety of erythromycin. An update of Swedish data. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24352632 |
He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
Rozov-Ung I et al. | Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. | 2014 | BMC Gastroenterol | pmid:24383478 |
Miyazaki M et al. | [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. | 2014 | Yakugaku Zasshi | pmid:24492229 |
Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
Pasquini L et al. | Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. | 2014 | Sci. Total Environ. | pmid:24631609 |
Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
Farabella I et al. | Allosteric signalling in the outer membrane translocation domain of PapC usher. | 2014 | Elife | pmid:25271373 |
Jaiswal N et al. | Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. | 2014 | PLoS ONE | pmid:25268974 |
Katayama Y et al. | Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. | 2014 | Brain Res. | pmid:25264351 |
Bauer CA and Grimme S | First principles calculation of electron ionization mass spectra for selected organic drug molecules. | 2014 | Org. Biomol. Chem. | pmid:25260171 |
Sugawara E and Nikaido H | Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli. | 2014 | Antimicrob. Agents Chemother. | pmid:25246403 |
Corona PS et al. | Case report: first report of a prosthetic joint infection caused by Facklamia hominis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25245196 |
Shen Y et al. | Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. | 2014 | ScientificWorldJournal | pmid:25110723 |
Tagawa J et al. | Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. | 2014 | J. Microbiol. Methods | pmid:25102110 |
Serna-Tamayo C et al. | Neonatal and infantile acne vulgaris: an update. | 2014 | Cutis | pmid:25101339 |
Kinouchi H et al. | Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. | 2014 | Biol. Pharm. Bull. | pmid:25087959 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Arakawa K | Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid. | 2014 | Biosci. Biotechnol. Biochem. | pmid:25036669 |
Pasquaroli S et al. | Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25017384 |
Dutra VG et al. | Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility. | 2014 | BMC Infect. Dis. | pmid:24919844 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Jing YR et al. | The synthesis of novel taxoids for oral administration. | 2014 | Bioorg. Med. Chem. | pmid:24332858 |
Kawaguchiya M et al. | Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. | 2014 | Microb. Drug Resist. | pmid:24766085 |
Gaudreau C et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli isolates obtained in Montreal, Quebec, Canada, from 2002 to 2013. | 2014 | J. Clin. Microbiol. | pmid:24759726 |
Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
Murphree CA et al. | Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. | 2014 | Curr. Microbiol. | pmid:24748439 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Moreno LZ et al. | Characterization of antibiotic resistance in Listeria spp. isolated from slaughterhouse environments, pork and human infections. | 2014 | J Infect Dev Ctries | pmid:24727506 |
Geng Q et al. | Molecular characterization and antimicrobial susceptibility of Streptococcus pneumoniae isolated from children hospitalized with respiratory infections in Suzhou, China. | 2014 | PLoS ONE | pmid:24710108 |
Lu B et al. | Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. | 2014 | Clin. Microbiol. Infect. | pmid:24118553 |
Zheng PX et al. | Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. | 2014 | Clin. Microbiol. Infect. | pmid:24118239 |
Singh P et al. | Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. | 2014 | Fundam Clin Pharmacol | pmid:24117516 |
Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. | 2014 | J. Fish Dis. | pmid:23992037 |