erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ragosta M et al. | Potentially fatal interaction between erythromycin and disopyramide. | 1989 | Am. J. Med. | pmid:2467560 |
Gumaste VV | Erythromycin-induced pancreatitis. | 1989 | Am. J. Med. | pmid:2729328 |
Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
Naot Y et al. | IgM and IgG antibody response in two immunosuppressed patients with Legionnaires' disease. Evidence of reactivation of latent infection. | 1982 | Am. J. Med. | pmid:6756135 |
Diehl AM et al. | Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. | 1984 | Am. J. Med. | pmid:6609640 |
Parker RH et al. | Erythromycin-resistant pneumococcal osteomyelitis. | 1970 | Am. J. Med. | pmid:5415405 |
Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
Wong KF et al. | Psittacosis-associated hemophagocytic syndrome. | 1991 | Am. J. Med. | pmid:1867249 |
Lipsky BA et al. | Ofloxacin treatment of Chlamydia pneumoniae (strain TWAR) lower respiratory tract infections. | 1990 | Am. J. Med. | pmid:2252040 |
Vianna NJ and Hinman AR | Rocky Mountain spotted fever on Long Island. Epidemiologic and clinical aspects. | 1971 | Am. J. Med. | pmid:5129543 |
DAVIS DS and ROMANSKY MJ | Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. | 1956 | Am. J. Med. | pmid:13354638 |
Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
Kugler JW et al. | Nosocomial Legionnaires' disease. Occurrence in recipients of bone marrow transplants. | 1983 | Am. J. Med. | pmid:6337488 |
Petersdorf RG | Antimicrobial prophylaxis of bacterial endocarditis. Prudent caution or bacterial overkill? | 1978 | Am. J. Med. | pmid:99033 |
Moellering RC et al. | Endocarditis due to group D streptococci. Comparison of disease caused by streptococcus bovis with that produced by the enterococci. | 1974 | Am. J. Med. | pmid:4843895 |
Moellering RC | Introduction: revolutionary changes in the macrolide and azalide antibiotics. | 1991 | Am. J. Med. | pmid:1656735 |
Neu HC | Clinical microbiology of azithromycin. | 1991 | Am. J. Med. | pmid:1656736 |
Bent S et al. | Antibiotics in acute bronchitis: a meta-analysis. | 1999 | Am. J. Med. | pmid:10403354 |
Stamm WE | Azithromycin in the treatment of uncomplicated genital chlamydial infections. | 1991 | Am. J. Med. | pmid:1656737 |
Hooton TM | A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. | 1991 | Am. J. Med. | pmid:1656738 |
Casiano RR | Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. | 1991 | Am. J. Med. | pmid:1656739 |
Dark D | Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. | 1991 | Am. J. Med. | pmid:1656740 |
Mallory SB | Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. | 1991 | Am. J. Med. | pmid:1656741 |
Hopkins S | Clinical toleration and safety of azithromycin. | 1991 | Am. J. Med. | pmid:1656742 |
Friedland L et al. | Ocular and pericardial involvement in Legionnaires' disease. | 1984 | Am. J. Med. | pmid:6507461 |
Schentag JJ and Ballow CH | Tissue-directed pharmacokinetics. | 1991 | Am. J. Med. | pmid:1656743 |
Nichols RL | Use of prophylactic antibiotics in surgical practice. | 1981 | Am. J. Med. | pmid:7011021 |
Wing EJ et al. | Successful treatment of Legionella micdadei (Pittsburgh pneumonia agent) pneumonia with erythromycin. | 1981 | Am. J. Med. | pmid:7304656 |
Nastro LJ and Finegold SM | Endocarditis due to anaerobic gram-negative bacilli. | 1973 | Am. J. Med. | pmid:4696007 |
Quintiliani R and Hymans PJ | The association of bacteremic Haemophilus influenzae pneumonia in adults with typable strains. | 1971 | Am. J. Med. | pmid:5314534 |
Dull JS et al. | Successful treatment of gastroparesis with erythromycin in a patient with progressive systemic sclerosis. | 1990 | Am. J. Med. | pmid:2220887 |
Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
Bor DH and Himmelstein DU | Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. | 1984 | Am. J. Med. | pmid:6711576 |
Unertl KE et al. | Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. | 1989 | Am. J. Med. | pmid:2589356 |
Trimble GX | Acute pancreatitis induced by erythromycin. | 1989 | Am. J. Med. | pmid:2589410 |
Singer DR et al. | Drug hypersensitivity causing granulomatous interstitial nephritis. | 1988 | Am. J. Kidney Dis. | pmid:3354573 |
MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
Mery JP and Kanfer A | Alterations in pharmacokinetics and ototoxicity of erythromycin in renal failure. | 1984 | Am. J. Kidney Dis. | pmid:6741942 |
Silang R et al. | Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. | 2001 | Am. J. Kidney Dis. | pmid:11157368 |
Ross EA and Koo LC | Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. | 1998 | Am. J. Kidney Dis. | pmid:9428453 |
Tanaka M et al. | Agranulocytosis induced by macrolide antibiotics. | 1995 | Am. J. Hematol. | pmid:7847332 |
Carbonell N et al. | Erythromycin infusion prior to endoscopy for acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. | 2006 | Am. J. Gastroenterol. | pmid:16771939 |
DiBaise JK et al. | Effects of low doses of erythromycin on the 13C Spirulina platensis gastric emptying breath test and electrogastrogram: a controlled study in healthy volunteers. | 2001 | Am. J. Gastroenterol. | pmid:11467630 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Fiorucci S et al. | Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. | 1994 | Am. J. Gastroenterol. | pmid:8147358 |
Camilleri M | The current role of erythromycin in the clinical management of gastric emptying disorders. | 1993 | Am. J. Gastroenterol. | pmid:8424415 |
Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
Mantides A et al. | The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. | 1993 | Am. J. Gastroenterol. | pmid:8424420 |
Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |