erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| OSKAM HJ | Determination of the sensitivity of bacteria to combinations of antibiotics in vitro; discussion of some results, especially with the combination tetracyclin-erythromycin. | 1956 | Acta Med Scand | pmid:13372188 |
| Asbjornsen G | The effect of different serum concentrations of antimicrobial drugs on the Lactobacillus leichmannii vitamin B12 assay. | 1973 | Acta Med Scand | pmid:4204166 |
| Nørregaard-Hansen K et al. | The significance of the enterohepatic circulation on the metabolism of digoxin in patients with the ability of intestinal conversion of the drug. | 1986 | Acta Med Scand | pmid:3766212 |
| Evangelista T et al. | [Acute polyradiculoneuritis associated with boutonneuse fever]. | 1994 Jul-Aug | Acta Med Port | pmid:7992646 |
| LIMSON BM and ARAGON PR | Current status of erythromycin. Laboratory and clinical studies on propionyl erythromycin. | 1959 Jul-Sep | Acta Med Philipp | pmid:13762201 |
| CHINAGLIA V et al. | [Passage into the aqueous humor of various antibiotics (tetracycline and erythromycin) administered by oral route]. | 1955 Apr-Jun | Acta Med Patav | pmid:13394159 |
| PRASAD AS | Severe urticaria following erythromycin therapy. | 1960 | Acta Med Iran | pmid:14488491 |
| Bejuk D | [Differentiation of resistance phenotypes among erythromycin-resistant streptococci]. | 2004 | Acta Med Croatica | pmid:15700686 |
| Benagiano A et al. | Effects of dextranase on experimental caries in the rat. | 1970 | Acta Med Acad Sci Hung | pmid:5512072 |
| Mager PP | Electronic and lipophilic interactions of macrolides (leucomycin derivatives) with ribosomal receptor sites. | 1980 | Acta Histochem. | pmid:6776777 |
| Thiele J et al. | Initial (latent) polycythemia vera with thrombocytosis mimicking essential thrombocythemia. | 2005 | Acta Haematol. | pmid:15983426 |
| Thiele J et al. | Mixed chimerism of erythro- and megakaryopoiesis following allogeneic bone marrow transplantation. | 2003 | Acta Haematol. | pmid:12853689 |
| Fiala M et al. | Pathogenesis of anemia associated with Mycoplasma pneumoniae. | 1974 | Acta Haematol. | pmid:4209353 |
| Peeters TL | Agonist effect of erythromycin and its analogues on motilin receptors. A new family of prokinetics? Clinical interest. | 1993 May-Aug | Acta Gastroenterol. Belg. | pmid:8266766 |
| Lang N et al. | On the mechanism of hormone action. VII. Induction by cortisol of a messenger RNA coding for tyrosine-alpha-ketoglutarate transaminase for an in vitro system. | 1968 | Acta Endocrinol. | pmid:4384442 |
| Rallis E et al. | Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. | 2013 | Acta Dermatovenerol Croat | pmid:24183219 |
| Ingham E | The effects of tetracyclines and erythromycin on complement activation in vitro. | 1990 | Acta Derm. Venereol. | pmid:1981435 |
| Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
| Mills O et al. | Bacterial resistance and therapeutic outcome following three months of topical acne therapy with 2% erythromycin gel versus its vehicle. | 2002 | Acta Derm. Venereol. | pmid:12361129 |
| Gudjónsson H | Experiments to induce febrile Jarisch-Herxheimer reaction in syphilitic rabbits with penicillin and erythromycin. | 1972 | Acta Derm. Venereol. | pmid:4118397 |