erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Gastroparesis D018589 2 associated lipids
Arthralgia D018771 8 associated lipids
Abdominal Abscess D018784 2 associated lipids
Sepsis D018805 11 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epidural Abscess D020802 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Ileus D045823 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Seroma D049291 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Occupational Injuries D060051 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
Barbanti F and Spigaglia P Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. 2016 Anaerobe pmid:27725230
Mayor-Ibarguren A et al. Periorificial Lesions in a Young Girl. 2016 Actas Dermosifiliogr pmid:26935746
DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Xu JY et al. Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. 2016 J. Proteome Res. pmid:27090497
Kang CH et al. Antimicrobial susceptibility of Vibrio alginolyticus isolated from oyster in Korea. 2016 Environ Sci Pollut Res Int pmid:27543129
Metcalf BJ et al. Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States. 2016 Clin. Microbiol. Infect. pmid:27542334
Parasrampuria DA et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. 2016 Br J Clin Pharmacol pmid:27530188
Hua CZ et al. [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. 2016 Zhonghua Er Ke Za Zhi pmid:27510868
Johanesen P and Lyras D Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. 2016 Methods Mol. Biol. pmid:27507343
Mikhail M et al. Orbital cellulitis and multiple abscess formation after strabismus surgery. 2016 Can. J. Ophthalmol. pmid:27085279
Chen Y et al. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. 2016 Carbohydr Polym pmid:27083368
Del Grosso M et al. ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. 2016 Antimicrob. Agents Chemother. pmid:27067338
Shi HY et al. [Effect of quorum sensing system on the infection of MRSA and the intervention of erythromycin on it]. 2016 Zhonghua Yi Xue Za Zhi pmid:27760665
Katayama Y et al. Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. 2016 Neurol. Res. pmid:27078702
Argyropoulos P et al. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. 2016 Biochim. Biophys. Acta pmid:26592346
Prabhasankar VP et al. Removal rates of antibiotics in four sewage treatment plants in South India. 2016 Environ Sci Pollut Res Int pmid:26797959
Seefeldt AC et al. Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. 2016 Nucleic Acids Res. pmid:26792896
Li M et al. Sugar-Grafted Cyclodextrin Nanocarrier as a "Trojan Horse" for Potentiating Antibiotic Activity. 2016 Pharm. Res. pmid:26792570
Lapierre L et al. Characterization of Antimicrobial Susceptibility and Its Association with Virulence Genes Related to Adherence, Invasion, and Cytotoxicity in Campylobacter jejuni and Campylobacter coli Isolates from Animals, Meat, and Humans. 2016 Microb. Drug Resist. pmid:26779841
Pan M and Chu LM Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. 2016 Ecotoxicol. Environ. Saf. pmid:26773832
Maye S et al. Transformation of serum-susceptible Escherichia coli O111 with p16Slux plasmid to allow for real-time monitoring of complement-based inactivation of bacterial growth in bovine milk. 2016 J. Dairy Sci. pmid:26585477
Nenquin M and Henquin JC Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells. 2016 Diabetes Obes Metab pmid:26584950
Wu H et al. In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea. 2016 Appl. Microbiol. Biotechnol. pmid:26552796
Boetsch C et al. Effects of Cytochrome P450 3A4 Inhibitors-Ketoconazole and Erythromycin-on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions. 2016 Clin Pharmacokinet pmid:26341813
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
Haenen CC et al. [Rosacea fulminans in pregnancy]. 2015 Ned Tijdschr Geneeskd pmid:26058762
Gagliotti C et al. A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. 2015 Acta Paediatr. pmid:26058421
Dermota U et al. Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. 2015 Int. J. Med. Microbiol. pmid:26055648
Drouet M et al. Endothelial Cell Toxicity of Vancomycin Infusion Combined with Other Antibiotics. 2015 Antimicrob. Agents Chemother. pmid:26055373
Zhou Y et al. Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. 2015 Talanta pmid:25770599
Tojima I et al. Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. 2015 Auris Nasus Larynx pmid:25769240
Hao H et al. Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. 2015 J. Appl. Microbiol. pmid:25766481
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Mills RO et al. Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. 2015 Infect Dis (Lond) pmid:25761718
Wu H et al. Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. 2015 Appl. Microbiol. Biotechnol. pmid:25549616
Cetecioglu Z et al. Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. 2015 Chemosphere pmid:25542637
Novak I and Kovač B Electronic structure of antibiotic erythromycin. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25528514
Kempe H et al. Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. 2015 Pharm. Res. pmid:25103333
Yang J et al. Improving heterologous polyketide production in Escherichia coli by transporter engineering. 2015 Appl. Microbiol. Biotechnol. pmid:26062534
Pavlova A and Gumbart JC Parametrization of macrolide antibiotics using the force field toolkit. 2015 J Comput Chem pmid:26280362
Aydın S et al. Inhibitory effect of erythromycin, tetracycline and sulfamethoxazole antibiotics on anaerobic treatment of a pharmaceutical wastewater. 2015 Water Sci. Technol. pmid:26038926
Bravo-Rodriguez K et al. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. 2015 Chem. Biol. pmid:26526102
Bérard A et al. Use of macrolides during pregnancy and the risk of birth defects: a population-based study. 2015 Pharmacoepidemiol Drug Saf pmid:26513406
Liao CH et al. DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. 2015 Appl. Microbiol. Biotechnol. pmid:26272095
Å mitran A et al. Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. 2015 Mem. Inst. Oswaldo Cruz pmid:26270594
Wang YL et al. Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. 2015 Foodborne Pathog. Dis. pmid:26258263
Prohl A et al. Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. 2015 PLoS ONE pmid:25768665
Enayati M et al. Virulence and antimicrobial resistance of Enterococcus faecium isolated from water samples. 2015 Lett. Appl. Microbiol. pmid:26249819